-1
votes
0answers
7 views

What does it mean when a protein has a different excitation spectra than wildtype, but the same emission spectra?

We have a GFP mutant that displays a different excitation spectra with emission at 510nm than the WT. However, their emission profiles with excitation at 490nm are the same, and we do not observe the ...
0
votes
0answers
4 views

Why would cancer cells want to use this downstream Ras pathway to inhibit GSK-3B?

GSK-3B causes targeting of B-catenin and cyclin D1 for destruction; therefore, the function of GSK-3B limits cell growth and proliferation. In Ras downstream pathway, activation of PI3K phosphorylates ...
0
votes
1answer
6 views

Does DNA polymerase always go the same direction?

I read that mutations are more likely to occur on "the strand that DNA polymerase replicates discontinuously". Does DNA polymerase always go replicate the same strand discontinuously, and if so, ...
-1
votes
0answers
18 views

Did (some) paedophilic attraction have adaptive value in ancestral times? [on hold]

Sorry in advance if this post offends anyone but I just want to look at the issue objectively. Paedophilic attraction is seen in all societies and its existence requires an explanation. Paedophilic ...
3
votes
1answer
25 views

Do we instinctially interpret birdsongs as a sign that there are no predators present?

I was outside today thinking how nice it was to hear the birds back from winter when I started thinking about the fact that we like bird song. It makes us happy in a very basic level, the sort of ...
0
votes
0answers
12 views

Why do Spiders make their web near the ceiling and near the light source ?

Why do spiders make their webs near the ceiling and near light sources ? Is it something like the spiders which choose to make a web near a light source survive, because they catch more insects as ...
3
votes
1answer
17 views

Applying kiwis on gelatin

Kiwis have the enzyme actinidain. This enzyme will break the peptide bonds from the gelatin. Making gelatin with raw kiwis will not work, because the peptide bonds in the gelatin will be broken down. ...
2
votes
1answer
60 views

Help me identify this insect

Over the last week or so as warmer weather has arrived, I've noticed small insects crawling around in the bathroom. I'm located in western Europe. They are perhaps 1mm in length, quite difficult to ...
1
vote
0answers
6 views

OCT-1 transport in Enterocytes

Does Oct-1 transport lactate or any of its products and in which direction (intracellularly to extracellular, the opposite, or inter-nuclear). The literature talks about Oct-1's role in neuronal ...
2
votes
1answer
20 views

Why are clementines easier to peel than oranges?

In my experience, clementines have been significantly easier to peel by hand than and orange. The skin of the orange seems to cling to the rest of the orange much more so than the skin of the ...
3
votes
0answers
31 views

How does the brain cool itself?

Thoughout life everyone tells you that brain is essentially a computer but just like computers your brain would create immense amounts of heat by being in use, so if that's the case how does it cool ...
2
votes
1answer
29 views

“bead” on a string theory of genetics, source?

Thomas Hunt Morgan was a pioneer in genetics and proposed the now false model of genes being "beads" on a string. These beads being indivisible and responsible for a single phenotype, if I understand ...
4
votes
0answers
30 views

Why do we get tired

At the end of a day full of work, it is general for people that their eyelids start to feel heavy. Laziness takes over and we begin to yawn. We all know that we're tired at that time, but why people ...
1
vote
1answer
21 views

What are the factors on which protein-protein interaction depend?

Does protein-protein interaction only happens when one of them is basic and the other acidic? Do protein interactions also depend on the protein structure? Are there more factors?
2
votes
1answer
23 views

DNA length and annealing kinetics

I have a mixture plasmids and undesired short linear fragments that share the same sequences. During denaturation and annealing, I would like the plasmids to 'find each other' before annealing to the ...
2
votes
1answer
33 views

If oxygen deficiency is bad even for a short while, why do people swim?

This may be trivia to many of you. Textbook says the oxygen deficiency, even for a short while can injure our cells. Then why do people go for sports like swimming? (where rhythmic breathing is ...
0
votes
0answers
12 views

Cell energy consumption and food intake

I am wondering if each cell in human body starts consuming ten percent more energy, how much food one has to consume compared to normal intake?
1
vote
0answers
21 views

If I fall into a pond with an algal bloom, could I die from the cyanotoxins? [on hold]

Suppose I fell into a pond with an algal bloom, and swam in it for a bit, but did not ingest any of the pond water (this is a hypothetical btw). Some algal blooms are harmful, containing natural ...
-1
votes
0answers
11 views

What is the explanation for forensic samples with abundant suspect's nDNA and no suspect's mtDNA at all? [on hold]

What is the explanation when DNA tests on the same biological trace show a perfect STR markers match for a person's nDNA but his mtDNA cannot be found in the same sample? And degradation must be ...
7
votes
4answers
290 views

Book/source for learning bioinformatics, focused on genomics?

Does anyone know of sources for learning bioinformatics, focused on genomics? I would like to learn alot of skills I could apply potently in the workforce if I ever became adept at the fields. My ...
2
votes
3answers
47 views

Why *morning walk*?

My PT teachers professes working-out/training in early morning hours is the best time to do so, a quick search on benefits of morning walk (or some similar phrase) reveals a lot of information which ...
1
vote
0answers
9 views

Does creatine-phosphate (CP) supplementation regenerate NADH?

I have the following facts: It is possible to convert ATP <-> creatine vice-versa. (ref - non scientific) CP supplementation protects against metabolic syndrome. ref1 ref2 Fructose digestion ...
0
votes
2answers
360 views

Did cats evolve from monkeys ? or vice versa?

Did cats evolve from monkeys ? or vice versa ? How similar are the genes of cats and monkeys ? What is the proof that they are related or that they are not related ? Most monkeys climb in trees and ...
0
votes
0answers
33 views

One targeted mutation that cause cell death?

Is there possibility to make one targeted DNA mutation in the cell, that will cause its death? My question: What gene (one) we need to target to cause cell death? (Human cells, searching for ...
0
votes
1answer
16 views

Do sodium channels keep renewing themselves with new subunits made by genes?

genes make alpha beta gamma subunits (proteins) to be used in making sodium channels... If I understand correctly? And so, since the genes keep making those subunits, does that mean new sodium ...
5
votes
1answer
29 views

Why can I see a light flicker when it's in my peripheral vision?

When I'm looking at an old CRT monitor or a worn fluorescent lamp, but not directly in the center of my gaze, the light from it seems to flicker. When I focus my gaze onto the monitor or lamp, the ...
-3
votes
0answers
40 views

Can my girfriend get pregnant if …? [on hold]

We just had sex my girlfriend and I for the first time. We had 3 runs, first run was unprotected, I did not ejaculated inside, but outside, then repenetrated unprotected. Second run was protected with ...
3
votes
0answers
23 views

Which sequence assemblers I can use to compare different paradigms?

I'm a high school student whose interested in bioinformatics. Therefore I chose a project which I study Sequence Assembly. My main goal is to compare different paradigms (Greedy, OLC, De Bruijn). I ...
0
votes
0answers
30 views

Do genes keep coding for sodium channels functions throughout life and not just once at beginning? [on hold]

Regarding the genes for sodium channel functions. Do the genes determine sodium channels functions and behaviors for life when the organism is an embryo? Or do genes continue coding how the sodium ...
1
vote
1answer
55 views

Is it possible to knock out a gene in adults?

gene knockout is mainly used in creating newborn animals... right? Well can you do it to already-adult animals or humans so that they themselves would experience change in their body and not just ...
2
votes
1answer
18 views

Literature that demonstrates organisms have a competitive advantage in numbers

I'm studying two bird populations that are competing against each other for a resource: Population A and Population B. Population A is present in much higher numbers than Population B, and as a ...
3
votes
0answers
14 views

What is the most reliable tumour suppressing gene for NSCLC?

I was looking at some tumour suppressing genes that can be helpful in diagnosing lung cancer (particularly NSCLC - Non-small-cell lung carcinoma) at an early stage. I came across a few such as p53, ...
5
votes
2answers
956 views

What has caused life to choose this unfathomably tiny subset of all possible proteins?

I wonder why life uses the particular proteins that it does, about 10^6 different proteins, I think? Evolution cannot explain it because the number of possible proteins is far far too large to ever ...
2
votes
0answers
11 views

Is emergence connected to nature's transition between fractal regimes at different size scales?

A fractal algorithm like Mandelbrot is self-similar in all size scales. This is not the case in nature. A tree is fractal in the sense that each branch is similar to the tree as a whole. But that is ...
1
vote
1answer
28 views

Which monkey species features two distinct male phenotypes?

I remember coming across a popular science article years ago about a monkey species which featured two male genotypes: the first were good looking males who acquired social status (as alphas or betas) ...
-1
votes
0answers
23 views

Increasing height after 21 years [on hold]

I am 21 years old guy and my height is only 5.4". Both my parents are short heighted. My family is also short heighted but my mom's family have a preety fair height. I have a younger brother and he is ...
1
vote
2answers
64 views

Non Coding DNA and its effect on evolution

I had a discussion with a friend of mine; from his understanding, bacteria and other small organisms have higher amounts of "coding" DNA and, as such, are able to evolve much faster than organisms ...
1
vote
0answers
13 views

Alder Tree Root Nodule Origins?

I recently found out that alder trees have root nodules which contain nitrogen-fixing bacteria and that alders are primary colonizers in primary succession. That leads me to this question: since there ...
-3
votes
0answers
56 views

Why are the palms of hand salty? [on hold]

I know that palms and soles have the highest sweat gland density. I am wondering if that is the only reason the palms and fingers on the flexor side get salty. Generally people wash their hand many ...
0
votes
1answer
44 views

Formation of life on other Planets [on hold]

At the present time it looks as if there is no other life in the Universe other than here on Earth . If this is true then why didn't it occur anywhere else ? Is it possible for something to happen ...
4
votes
1answer
38 views

What's a mouth ulcer/canker sore “made of”, and why do they develop?

Mouth ulcers are red/white rings with a crater. They are sore and last for 7-10 days. What I want to know is what they are 'made of' - i.e., what is the ring filled with, and why is the centre crater ...
6
votes
1answer
46 views

Latency in our senses

I would be interested in knowing how long it takes between the moment something touches our skin and the moment something is activated in the brain. Also how long does it take in total until we ...
3
votes
0answers
23 views

Photolysis of Water?

In chemistry, I studied the decomposition of water as being $2H_2O_{(l)} \rightarrow 2H_{2(g)} + O_{2(g)}$. However, when water is split, the equation is $2H_2O_{(l)} \rightarrow 4H^+ + 4e^- ...
4
votes
1answer
37 views

Powdered meal replacement vs regular meal

Can a person live with this alternative nutrition? Of course, assuming that eating pleasure is assumed the same. The nutrients that contain are far better than average meal a person eats the majority ...
2
votes
0answers
21 views

The ring formation of ringworm

I know ringworm is caused by a fungus on the skin, nails or scalp but what causes the rash to form as a ring instead of like a normal spread out rash?
1
vote
0answers
11 views

Surface Power Density of Fluorescing Reaction

I am looking to find out what is the ballpark power density of a fluorescing PCR reaction using a SYBR Green or Taq Man dye might be. Is it on the order of $E_e=1mW/cm^2$, less or more? Any help of ...
-1
votes
0answers
15 views

ncbi+ build blast_demo app [on hold]

Has anyone recently been building the ncbi+ toolkit? My question is: What is the minimum required configuration to build blast_demo app? Because I have tried to make only the core lib and that takes ...
0
votes
1answer
18 views

Energy consumption of a resting synapse

What is the energy penalty of maintaining rarely used synapse? I'm wondering if forgetting is cheaper than remembering unnecessary details.
-1
votes
0answers
27 views

How do disinfectant sprays work? Difference with antibiotics [on hold]

Most disinfectants say they kill 99.9% of germs, I'm wondering how do they do that exactly. Also, there are bacteria resistant to the most powerful antibiotics. Would a disinfectant kill them anyway ...
0
votes
0answers
14 views

Do aerobic bacteria precipitate in a liquid culture?

In most books aerobic bacteria is shown growing only at the top of a static liquid culture tube? Shouldn't have precipitated instead of floating on the surface?

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