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Acetyl-CoA has a number of biochemical roles in the body and I'm curious as to whether anybody knows where I can find at least a semi-comprehensive list (i.e. comprising all the major roles in the human body it serves) of the biochemical reactions in which acetyl-CoA partakes in the human body.

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Have you tried wikipedia? All the major ones should be there. – terdon Sep 4 '13 at 13:47
up vote 1 down vote accepted

I may be missing some fantastic resource, but my first thought is to send you to KEGG. Is that crazy? Maybe, but a simple search for Acetyl-CoA in humans can give you tons of useful information, including GO terms, enzymes, genes, and, yes, biochemical reactions; just use the KEGG Pathways tool and specify humans (hsa). You can click on each individual pathway for more information, such as the cholinergic synapse.

Cholinergic synapse pathway

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Are these reactions solely those that occur in the human body? – Brenton Horne Sep 4 '13 at 13:49
@BrentonHorne Wow sorry, I TOTALLY missed that! It's now updated to be homo sapiens only. – Amory Sep 4 '13 at 13:59

Metacyc is an excelent methabolic pathways database that includes all kind of organisms. Of course you can search for methabolic compound.

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You should look at Lehninger's Principles of Biochemistry. Just search for Acetyl-coa in the index, and you will find it's roles in different aspects of the metabolism.

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