Take the 2-minute tour ×
Biology Stack Exchange is a question and answer site for biology researchers, academics, and students. It's 100% free, no registration required.

I've searched the internet for several minutes and I've looked at DAT but I'm having trouble finding the DAT binding location. Where (and to which aa) does dopamine and cocaine bind to hDAT1?

share|improve this question
add comment

1 Answer

up vote 2 down vote accepted

The following paper answers your question in detail:

http://www.ncbi.nlm.nih.gov/pubmed/18568020

It seems like the following aa are responsible for the binding, but please refer to the paper for more details:

Val152,Tyr156,Asn157,Ser422,(Asp79)

share|improve this answer
    
thank you very much –  caseyr547 Sep 19 '13 at 1:44
add comment

Your Answer

 
discard

By posting your answer, you agree to the privacy policy and terms of service.

Not the answer you're looking for? Browse other questions tagged or ask your own question.