the SCOP project did this. scop.mrc-lmb.cam.ac.uk/scop
which far more than 10,000 proteins. their goal was to categorize the protein folds that were known through X-ray and NMR structures. their current status:
38221 PDB Entries. 1 Literature Reference. 110800 Domains. (excluding nucleic acids and theoretical models).
It was last updated in 2009 though.
There is a broad literature where researchers evaluate the geometry of tens of thousands of structures. A review of all of them would be more like a book than an answer to a question on stackexchange!
Their goals range quite broadly; "how does the protein sequence dictate secondary structure?" or quite narrow "how does this specific metabolic enzyme change in structure across many organisms"?
If you can think of something more specific I'll do my best to respond. if you want to know how to do this I can also help with that.