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Standard models in population genetics look up at the evolution of few loci which impact fitness. The variance in fitness is determined by the genetic variance and the environmental variance (and the co-variance between environment and genetics). In this question I am interested only about genetic variance and about what percentage of the total genetic variance in fitness do $n$ loci explain.

The question is:

In general, in natural populations, what percentage of the total genetic variance is explained by the $n$ most important loci? Here, by "most important loci" I mean loci which variance explain much of the total genetic variance.

In other words, the subquestions are of the kind:

  • how much of the fitness variance does the most important locus explain?
  • How much of the fitness variance do the 3 most important loci explain?
  • How much of the fitness variance do the 100 most important loci explain? … or if you prefer…

It is obvious that the answer depends on the population under consideration. Factors that might influence the answers are for example

  • species
  • population size
  • environment stability

Beside this question, I also welcome some insights concerning how different factors are likely to influence the answer.

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Do you have at least one example of an empirical study of the type you are looking for ? It may be a helpful starting point for us in finding other ones. –  Barbara Feb 10 at 13:16
No, unfortunately I don't know any empirical study that investigates my question. –  Remi.b Feb 10 at 14:25
And do you have any study, which measures percentual increase in fitness, regardless of the cause ? –  Barbara Feb 10 at 14:33
Could you phrase this in terms of just one question? –  Atticus29 Sep 21 at 3:00
@Atticus29 Thanks for your comment. I updated my post in order to have one clearly stated question. Does my question makes sense to you? –  Remi.b Sep 21 at 3:41

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