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I have this figure about nitric oxide and tumor which is for schematic for me to understand it

enter image description here

The figure should probably say that tumour cell is induced by NO or alone to go apoptosis and it eventually dies. Another possibility is that tumour cell continuous to be tumour cell after NO stimulation.

RNS is derived from nitric oxide and superoxide produced via the enzymatic activity of inducible nitric oxide synthase 2 (NOS2) and NADPH oxidase, respectively. NOS2 is expressed mainly in macrophages after induction by cytokines and microbial products, notably interferon-gamma (IFN-gamma) and lipopolysaccharide (LPS).

So I think i-NOS represents the NOS2 here. I think you need cyclic CMP for energy production, not sure. Stimulated angiogenesis leads to increased nitric oxide production which is then used to derive i-NOS + cGPM, I think deducing from the picture.

How can you make this schematic figure more exact?

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Where did you get this figure? It looks a bit incomplete? –  Chris Feb 5 at 17:13
@Chris Thank you for boost! I fixed the picture. –  Masi Feb 5 at 18:10

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