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I am not a biology student, but just want to know if GULO gene are present only in mammals or all species possess it ?

And is GULO gene active in human fetus?

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GULO encodes L-gulonolactone oxidase which catalyses a step in the biosynthetic pathway to ascorbic acid (vitamin C).

I did a BLAST search at NCBI using the mouse GULO protein as probe, excluding mammals, and I saw highly significant hits in reptiles, birds, sea urchins, fungi and bacteria. I conclude that this enzyme, (or very close relatives) is ubiquitous.

Humans (and other primates; also guinea pigs and the Dalmatian coach hound) have a defective GULO gene and so require dietary ascorbate.

Since the gene is non-functional in humans it isn't expressed in the foetus.

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+1 Finally I got to know why humans and guinea pigs need dietary Vitamin C. –  biogirl Feb 22 at 16:41
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