Sign up ×
Biology Stack Exchange is a question and answer site for biology researchers, academics, and students. It's 100% free, no registration required.

The telomerase is an enzyme that adds telomeres.

What stops the telomerase from adding too many telomere sequences ? What's the regulating mechanism ?

share|improve this question

1 Answer 1

up vote 3 down vote accepted

Telomerases are tightly controlled on all level: Expression, post-translational modifications and by external factors. I think for this the external factors, a protein class called telomeric proteins. They bind to the end of the telomere and regulate the telomerase.

enter image description here

The figure is from this paper, which looks into the topic quite extensively:

share|improve this answer

Your Answer


By posting your answer, you agree to the privacy policy and terms of service.

Not the answer you're looking for? Browse other questions tagged or ask your own question.