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The telomerase is an enzyme that adds telomeres.

What stops the telomerase from adding too many telomere sequences ? What's the regulating mechanism ?

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up vote 3 down vote accepted

Telomerases are tightly controlled on all level: Expression, post-translational modifications and by external factors. I think for this the external factors, a protein class called telomeric proteins. They bind to the end of the telomere and regulate the telomerase.

enter image description here

The figure is from this paper, which looks into the topic quite extensively:

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