Take the 2-minute tour ×
Biology Stack Exchange is a question and answer site for biology researchers, academics, and students. It's 100% free, no registration required.

I am analysing this picture about acute hepatitis, viral infection of HBV, where are standard antibodies and antigens of HBV:

  • HBsAg serum antigen
  • HBeAg some antigen in blood
  • anti-HBc antibody in blood
  • IgM and IgG are immunoglobulins for antibodies HBc as diagnostic tests

enter image description here

The curve Anti-HBc intersects with HBeAg and starts symptoms. I am interested what this intersection mean. Can you think it as analogue to heart's valves and pressure? The amount of Anti-HBc becomes more than HBeAg which exposes the Anti-HBc to some cells. When HBeA then intersects with level of detection (no more HBeAg in blood), so the exposure of Anti-HBc to cells ends and symptoms end. HBeAg seems to be analogously like a key to symptoms.

How do you interpret the intersections of these two curves?

share|improve this question
Can you please introduce your abbreviations? –  Chris Mar 27 at 12:04
I added some definitions of the terms. –  Masi Mar 27 at 19:02

Your Answer


By posting your answer, you agree to the privacy policy and terms of service.

Browse other questions tagged or ask your own question.