I am thinking this figure
It suggests me that there has to be Sepsis that infection can lead to SIRS.
I am thinking particularly the pathogenesis of Cryptococcus neoformans where
- respiratory tract $\to$ pulmonary infection $\to$
- asymptomatic and nonspecific pulmonary signs in normal patients
- progressive systemic disease in immunocompromised patients
and the last row.
Can SIRS occur without preceding or simultaneous Sepsis?