I have a problem in my reasoning on the fatty acid synthesis in the human body. In the synthesis proces you have this dimere or dimeer or I don't know how you call it in English, and it excists out of 2 same monomeres.
So the synthesis starts with the transfer of a acetylgroup from acetylCoA to the sulfhydrylgroup of the condensing enzyme (CE) with help of the acetyltransferase enzyme (AT) and this on 1 of the 2 monomeres.
At the same time a malonylgroup from malonylCoA is transfered to the sulfhydrylterminus of fosfopantetheïn from the ACP, and this on the other monomere and with help of the malonyltransferase (MT) enzyme.
AND HERE THE PROBLEM STARTS
The acetylresidu will be condensing with the malonylACP and at the same time there will be a decarboxylation (CO2 goes off) and CE goes off from acetyl. At the end acetoacetylACP is formed. So if I got it right; the acetylresidu is being 'cut off' from the CE from the first monomere and binds to the malonylACP on the other monomere. Right?
And after that the acetoacetylACP will be swept back to the other monomere (to the reduction part), is this also right?
Then the reduction-dehydration-reduction steps are happening and at the end of the road you will get butyrylACP which will cut off from the ACP and migrate on the same monomere to the cysteïnresidu at the condensing enzyme (CE) (= translocation).
And after that you can start a new condensation-reduction-translocation cycle and go on until you end up at palmitoylACP.
So the actual question is; is my reasoning right about how the product is going from one monomere to the other several times? In my book it's a pretty messy explanation and so I want to be sure I'm right.
I hope somebody can help me out =)