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I recently had a question about how to distinguish the origin of variations in the sequences of rRNA as to whether alterations are generated by genetic drift or natural selection. For me it has not been possible to distinguish between the effect of the two evolutionary forces, then the result is still the same. Is there some method proposed to define the origin of the variation between pairs of DNA sequences from these evolutionary forces? How could this insight?

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Are you searching for this: Research article Genome-wide estimation of firing efficiencies of origins of DNA replication from time-course copy number variation data (link.springer.com/article/10.1186%2F1471-2105-11-247) –  Devashish Das Jul 14 at 7:43

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