I get conflicting answers. One would think if it was true, it would be rather seminal and widely known.
But more recent papers like this one still openly ask the question, and that the only thing we know is that the initial ribosome binding step is similar between RNA and DNA.
I can't reconcile these papers.
- Morgan AR, Wells RD, Khorana HG. 1967. Studies on polynucleotides. LXXIV. Direct translation in vitro of single-stranded DNA-like polymers with repeating nucleotide sequences in the presence of neomycin B. Journal of Molecular Biology, 26(3):477-497, doi:1016.10/0022-2836(67)90316-6.
- McCarthy BJ, Holland JJ. 1965. Denatured DNA as a direct template for in vitro protein synthesis. Proceedings of the National Academy of Sciences USA, 54(3):880-886.
- Bretscher MS. 1969. Ribosome Initiation and the Mode of Action of Neomycin in the Direct Translation of Single-Stranded fd DNA. Cold Spring Harbor Symposia on Quantitative Biology, 34:653-651, doi:10.1101/SQB.1969.034.01.075.
- Damiana L, Marty-Detravesa C, Winterhalterc M, Fourniera D, Paquereaua L. 2009. Single-strand DNA translation initiation step analyzed by Isothermal Titration Calorimetry. Biochemical and Biophysical Research Communications, 385(3): 296-301, doi:10.1016/j.bbrc.2009.05.044.