Take the 2-minute tour ×
Biology Stack Exchange is a question and answer site for biology researchers, academics, and students. It's 100% free, no registration required.

I have a question in regards to my HIV test research. The rapid tests like Orasures Oraquick contains a strip of synthetic peptides that are used to represent proteins found in the envelope region of the virus. The test itself uses a solid phase where the antigens are located so that they can be immobilized. My question is, when these immobilized antigens come into contact with the reagent inside of the test, can they become unimmobilized and travel through the test? Or are they permanently placed in the solid phase? Any info would be warmly appreciated!

share|improve this question

closed as off-topic by Chris, Bez, Chris Stronks, GriffinEvo, Cornelius Dec 5 at 15:12

  • This question does not appear to be about biology within the scope defined in the help center.
If this question can be reworded to fit the rules in the help center, please edit the question.

Whilst I don't know the specifics of the test you mention, I'd be very surprised if they could move after being fixed into place. Otherwise the line indicating a positive response may not appear due to diffusion of the antigens away from the line they are fixed into. –  Rory M Dec 26 '12 at 19:32
This question will be hard to impossible to answer without detailed knowledge of the test conditions. –  Chris Dec 5 at 9:59