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I'd like to add a cell penetrating peptide to my custom peptide (30aa). Can I just add it to the end of the peptide sequence or does it have to be positioned on an outward facing external chain?

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up vote 3 down vote accepted

This papers tables shows that cell penetrating peptides are placed before their cargo peptide and do not need to be on a side chain. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1576229/table/tbl1/

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