Sulforaphane is a isothiocyanate found in cruciferous vegetables including broccoli and cauliflower. Its 2D structure is as follows:
It's been found to serve as a histone deacetylase 6 (HDAC6) inhibitor and to inhibit androgen receptor expression in prostate cancer cells.1 This caused me to become curious as to whether it would do the same in lower motor neuron cells and thus manage to prevent their polyglutamine-induced death and thus halt the progression of spinobulbar muscular atrophy (SBMA; Kennedy's disease).
