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Which mixed opioid agonist/antagonist are approved for Human Use in Europe and/or the USA? I know of:

  • Buprenorphine
  • Butorphanol
  • Nalbuphine
  • Pentazocine

Are there any others? If so I would like you to list their respective partition coefficients ($\log{P} $), binding affinities (Ki), EC50's, IC50's at the opioid receptors ($\kappa$, $\delta$, $\mu$), binding profile and countries where they are approved for clinic use.

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closed as too broad by WYSIWYG, The Last Word, Chris, GriffinEvo, fileunderwater Dec 8 at 8:47

There are either too many possible answers, or good answers would be too long for this format. Please add details to narrow the answer set or to isolate an issue that can be answered in a few paragraphs.If this question can be reworded to fit the rules in the help center, please edit the question.

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This question appears to be off-topic because it not a biology question. –  GriffinEvo Dec 8 at 8:22

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