Which mixed opioid agonist/antagonist are approved for Human Use in Europe and/or the USA? I know of:
- Buprenorphine
- Butorphanol
- Nalbuphine
- Pentazocine
Are there any others? If so I would like you to list their respective partition coefficients ($\log{P} $), binding affinities (Ki), EC50's, IC50's at the opioid receptors ($\kappa$, $\delta$, $\mu$), binding profile and countries where they are approved for clinic use.
