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Tianeptine is an antidepressant and anxiolytic that has some additional analgesic properties that's used in some European countries, and the theories I've heard about how it works include the following:

  • Inducing dopamine release in the mesolimbic reward pathway.
  • Potentiating the AMPA glutamate receptors.
  • Interacting in some way with the Adenosine, A1 receptor.



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so what's wrong with these theories? Wikipedia has some links to others if you're interested... –  MattDMo Apr 13 '13 at 14:08
Just wondering if there are any additional theories. –  Brenton Horne Apr 13 '13 at 14:44

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