Biology Stack Exchange is a question and answer site for biology researchers, academics, and students. It's 100% free, no registration required.

Sign up
Here's how it works:
  1. Anybody can ask a question
  2. Anybody can answer
  3. The best answers are voted up and rise to the top

I understand that there would have to be a portion of liver present to regrow from, so how much liver would the minimum to be able to regrow?

By what mechanism does regrowth occur?

share|improve this question
up vote 4 down vote accepted

At least 25% of the original liver seems to be the minimum for regrowth.

The initial regrowth is due to proliferation of hepatocytes: they exit G0 and enter mitosis. The ECM dissolves and is remodeled; the cholangiocytes and SECs also divide.

If you want to read more, you can visit the Google books link above, and the preview lets you read several pages on liver regeneration in rodents. (If it doesn't work, try changing the URL to your current location: is US, is Canada, etc.)

share|improve this answer

Your Answer


By posting your answer, you agree to the privacy policy and terms of service.