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What naturally produced drug causes a 'tingleing euphoric rush' through your body, as well as a 'wave of goosebumps'?

I've always been interested in this sensation, two of the last times i can distinctively remember feeling it are:

  1. Watching the movie Philadelphia, when you hear the courts verdict on Andrew Beckett's (Tom Hanks) case.

  2. A horse I backed won narrowly after a neck to neck final dash.

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Sorry if the question seems pretty basic, I couldn't think of a way to better articulate it.

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1  
well, let's see - cocaine, heroin, amphetamines, caffeine, morphine, marijuana, nicotine... pretty much any addictive substance will give you pleasurable feelings just like you describe, because they (among other things) stimulate the release of endorphins, which activate your brain's pleasure centers. Fortunately, lots of other things can give you similar experiences, like music, great art, friendships, sex, racing, skydiving... all of the good things in life. –  MattDMo Jun 25 '13 at 2:01
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It's most likely not a substance, but an activation of a certain brain region, in which case it would be a neurotransmitter. Potential candidates are serotonin , dopamine, norepinephrine and choline. –  Alex Stone Jun 26 '13 at 1:12
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