I'm looking at different genotyping profiles available at opensnp.org and am trying to compare profiles for people with different phenotypes.
For example, given 10 profiles of people who can roll their tongue and those who cannot, I am trying to identify what is different between these people and what's similar.
A typical record is in this format:
Rsid, chromosome, Position on chromosome, actual 2 letter mutation
How can such records be compared to identify similarities for a given phenotype? Does RSID uniquely identify a mutation, or is it a combination of rsid and position?
In other words, if one user has rsid 123 at position 555 and another one has rsid 123 at position 666, and the mutation is the same, is this a similarity, or does position matter?