Biologically-synthesized chemicals (or their derivatives) that cause growth suppression or death of bacteria. Other anti-microbials are often also considered under the class antibiotics these days.

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Could viruses be used as antibiotics?

Could we use viruses that only affect bacteria to act as antibiotics? The more bacteria, the more times the virus divides, so the stronger it gets. Is this practical?
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1answer
5k views

Why does Penicillin only affect bacterial cell walls

I was quite fascinated by the feature Should Science Pull the Trigger on Antiviral Drugs—That Can Blast the Common Cold? in this month's Wired magazine. They explain that Penicillin is effective at ...
11
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2answers
677 views

Antibacterial hand soaps (and related products); what are they good for?

From Wikipedia: Household use of antibacterials in soaps and other products, although not clearly contributing to resistance, is also discouraged (as not being effective at infection control). ...
10
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2answers
4k views

Why would taking antibiotics increase stamina and energy?

I often hear that people who are taking antibiotics experience wild fluctuations between feeling full of energy and completely alert but soon after feeling impossibly fatigued and sick. Does this ...
9
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3answers
31k views

What is the difference between an antibiotic and an antibacterial?

Concerning medicine, what are the differences between antibiotics and antibacterials?
9
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2answers
709 views

How are antibiotic resistant bacterial infections treated?

For example, how are infections of antibiotic resistant strains of MRSA, Streptococcus, or Gonorrhea treated?
9
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2answers
460 views

Do antibiotics attenuate immune response on subsequent exposure to same bacteria?

A healthy immune response to a bacterial infection includes "memory" to permit the body to thwart subsequent exposure to same bacteria. What are the dynamics of using antibiotics on initial exposure ...
9
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1answer
245 views

How can antibiotics damage the ear?

What is the mechanism by which aminoglycoside antibiotics (such as streptomycin and gentamicin) damage the mechano-sensory hair cells of the auditory and vestibular system? (Could this be seen as ...
8
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3answers
1k views

Why is triclosan not considered an antibiotic?

Triclosan is a chemical often referred to as a "biocide" instead of an "antibiotic". However, its mode of action seems to suggest that it is an antibiotic. Triclosan binds to bacterial enoyl-acyl ...
7
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2answers
4k views

Why are antibiotics prescribed with a viral infection like a cold?

I've heard both ways; people going to the doctor for a cold and then getting a prescription for antibiotics and those that go to the doctor and told they have ride it out because it's a viral ...
7
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1answer
511 views

Aren't antibiotic resistant probiotics dangerous?

Multidrug resistant probiotics are often recommended by doctors in various cases. But since bacteriae can easily exchange genes by conjugation or other means they could promote the drug resistance of ...
6
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1answer
196 views

What are the positive effects of wrongful antibiotic use on a viral infection?

I categorically accept that bacteria differ from viruses; so antibiotics DON'T help in viral infections. I also read this and this; so no need to explain this. I've read about the negative effects (eg ...
6
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1answer
261 views

What is the impact of sertraline on white blood cells?

This simplified video and RT.com article discusses how the mechanics of the death of a white blood cell can be useful as an "alert mechanism" to other white blood cells of an incoming infection. Also ...
6
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1answer
2k views

Why don't antibiotics affect mitochondria?

Given that mitochondria are evolutionarily closely related to bacteria, and antibiotics kill bacteria, why don't antibiotics also kill mitochondria?
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1answer
1k views

Could alcohol be used as an antibiotic?

I was thinking about how alcohol is used to sterilize, and I was wondering if it would be possible to use alcohol as an antibiotic? if it kills bacteria, couldn't (conceivably) alcohol in the ...
5
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3answers
114 views

Is 100% antibacterial resistance possible?

The quest to develop antibacterial and antibiotic substances has often been described as an arms-race, as bacterial life develops resistance, requiring us to develop novel agents which can effectively ...
5
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2answers
150 views

Can Helicobacter pylori be eradicated naturally?

This question is not to discuss whether substances that have anti-H. pylori activity work or not, or to discuss the pros and cons of such but from a medical perspective. Assuming that one is able to ...
4
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1answer
85 views

Bacteria resistance to natural antibiotics? [duplicate]

It is a known fact that bacteria develop immunity to antibiotics. Why then did not all bacteria develop immunity to natural antibiotics like penicillin in the fungi? It is for sure that fungi did not ...
4
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0answers
45 views

How does drug-induced photosensitivity work?

Some drugs (tetracyclines, for instance) can cause photosensitivity reactions—that is, some patients become extremely sensitive to the sun, developing rashes or inflammation after spending time ...
3
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3answers
880 views

If ants have an antibiotic gland, how can they spread hospital infections?

Wikipedia describes how antibiotics are produced in ants: "Metapleural glands ... are responsible for the production of an antibiotic fluid that then collects in a reservoir ... also referred ...
3
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2answers
371 views

Does antibacterial soap work chemically?

Normal soap requires scrubbing, does anti-bacterial soap require scrubbing too? Since it (I assume) works chemically, can I produce the same cleansing effect without lathering with soap and using anti-...
3
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2answers
87 views

Why does azithromycin not affect human mitochondria?

Drugs like tetracyclines, macrolides and aminoglycosides bind to prokaryotic ribosomes. It is interesting that our body too having mitochondria, which have prokaryotic ribosomes, there is little(?) ...
3
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1answer
151 views

Does long term use of antibiotics in humans actually lead to a greater risk of infection?

I've read about the overuse of antibiotics leading to antibiotic resistant strains of bacteria, so generally does long term use of antibiotics breed these strains in the bodies of antibiotic users and ...
3
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1answer
17 views

How do antibiotics combined with a non-Western diet affect weight loss?

Wikipedia describes a Western diet as: ... higher intakes of red and processed meat, butter, high-fat dairy products, eggs, refined grains, white potatoes, french fries, and high-sugar drinks. ...
3
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0answers
105 views

What is this red liquid produced by a fungal colony?

In a jar, where I had some orchid plants, a fungi start growing few days ago. I removed the plants and let the fungi to expand and grow more. After some days, red drops started to appear on the ...
2
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1answer
882 views

Why does ampicillin in solution turn yellow?

I have a universal tube with 10 mg mL-1 ampicillin. When I got it, it was supposed to be sterile. It was opened for approximately 20 minutes for an experiment and has since been standing around sealed ...
2
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1answer
83 views

Quorum Sensing in Vibrio cholerae

This is a figure summarising the quorum sensing mechanism in Vibrio cholerae. In this video by Bonnie Bassler, she explains how quorum sensing can be targeted to control infections. At 15:09 she ...
2
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1answer
56 views

What does completing the course of antibiotics accomplish?

This article from the WHO states: If you stop treatment early, there is a risk the antibiotics won’t have killed all the bacteria that made you sick and that it will mutate and become resistant. ...
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0answers
32 views

“Antibiotic resistance” equivalent in archaea for selection during cloning

I'm beginning to work with halophilic archaea and I'm trying to figure out a good way to select for cells that have taken up a plasmid. Obviously, one can't use antibiotic resistance since they are ...
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2answers
2k views

Why do antibiotics have a special importance when taking lactulose?

“Before taking lactulose, tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially antacids, antibiotics including neomycin (Mycifradin), and other ...
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2answers
746 views

By what mechanism does penicillin resistance usually develop in Streptococcus pneumoniae?

There are three mechanisms: prevention of the interaction between antibiotic and the target PBP; modification of the binding of the antibiotic to the PBP; hydrolysis of the antibiotic by a ...
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1answer
39 views

Comparative effectiveness of antibiotics against colonies and growing bacteria

Appropriate antibiotics usually eliminate bacteria. However are the same antibiotics as effective against bacteria that have grown to form a colony?
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1answer
47 views

Are there antibiotics for all bacteria somewhere in the earth? [closed]

When I read about Penicillin, I found that it came from a green mold to protect itself. If all bacteria and/or molds in competition to survive, can we believe that there is an antibiotic for each ...
1
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1answer
37 views

Correlating Ki values of pesticides to bacterial growth

Four pesticides P1 to P4 are reversible inhibitors of an enzyme E that is essential for the growth of a bacterium B. Their Ki values are given in the table below. Each of these four pesticides is ...
1
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1answer
425 views

Where are doxycycline's anti-inflammatory properties derived from?

I have been looking at this antibiotic called doxycycline which is used mainly as an antibiotic. It has however some interesting anti-inflammatory properties. Does anyone know where these anti-...
1
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0answers
30 views

After a bacterial infection is dealt with, do any of that colony of bacteria remain?

Suppose that I get a bacterial infection, which my immune system deals with. Are there any remnant bacteria, or are they all gone? Now consider the same scenario, but having been treated with a full ...
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0answers
19 views

Effective Mycoplasma Elimination from Primary Human Cultures

Obviously the best way to avoid mycoplasma contamination is to avoid it in the first place. In our case, however, it is not possible to avoid. We are culturing viruses and tissues out of human nasal ...
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0answers
34 views

Why are treatment periods with antibiotics longer than 1-2 days?

Antibiotics are given prophylactically for several indications (e.g. prior to dental surgery). Why are the treatment periods for prophylactic antibiotics much shorter than when treating an ...
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0answers
59 views

Why doesn't one develop immunity to bacterial STIs?

Why doesn't one develop immunity to STIs such as Chlamydia/Gonorrhea and Syphilis even after the first exposure and treatment with antibiotics?
1
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3answers
429 views

Can ampicillin resistant bacteria survive penicillin plate?

in my molecular bio class we were asked a trick question: If the bacteria has a plasmid with that grants it ampicillin ressistance, can the bacteria survive if placed in penicillin? I gave it a ...
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0answers
27 views

Do bacteria develop a resistance to antimicrobial peptides at the same rate as against “regular” antibiotics?

From what I understand, antimicrobial peptides are roughly grouped into three structural sets, with large variations present between different groups as well as within the groups. Their anti-microbial ...
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2answers
58 views

Could a prolonged amount of Antibiotics severely affect the digestion Gut Microbiota?

Could taking antibiotics for a prolonged amount of time severely harm or even worse kill off a large proportion of Gut Microbiota responsible entirely for digestion, Resulting in lifelong digestion ...
0
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1answer
131 views

How much penicillinase is needed to deactivate 125mg of amoxicillin?

How much penicillinase is needed to deactivate 125mg of amoxicillin? Penicillinase in penase concentrate from CPC. 20,000 Levy Units/ml/min I need IU of 125 mg of amoxicillin. Please note that the ...
0
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1answer
38 views

Is it possible for bacteria to acquire family-wide antibiotic resistance?

If there is bacteria, lets say Enterococci that is sensitive to: Amoxycillin-Clavulinic acid Ampicillin-Sulbactam Ofloxacin Ciprofloxacin Is it possible to ...
0
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1answer
46 views

Downstream analysis after in vivo pathogen RNAseq

We performed RNA-Seq of in vivo bacterial samples and identified some key up- and down-regulated pathways. We compared bacteria during infection with conventional agar plate. Which could be the next ...
0
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1answer
99 views

What attracts cells to: pathogens, professional antigen-presenting cells, and cells with an antigen on its MHC-1 protein?

I have a few questions in regards to attraction/stimulation in the immune system. What attracts leukocytes and antibodies to pathogens in the first place? What attracts CD4+ cells to professional ...
0
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1answer
329 views

How the concentration of an antibiotic is chosen for YPD medium?

I need to prepare YPD plates containing hygromycin, but I don't know which concentration I can use. I'll select transformants of Hansenula polymorpha.
0
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1answer
28 views

How can you develop a bacterial infection when taking antibiotics for another area of the body with a bacterial infection? [closed]

How can you develop a bacterial infection when taking antibiotics for another area? For example, "if someone was prescribed an antibiotic for a bacterial infection of the throat and while taking the ...
0
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0answers
27 views

30s ribosomal Inhibitor (Antibiotic)Question

I have a question regarding the mode of action of 30s ribosomal Inhibitors (antibiotcs) - tetracyclines. According to some online resources, the antibiotics enter the A-site, which prevents other tRNA ...
0
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0answers
19 views

Feasibility of “smart effective microorganisms”

This might be a stupid question as I have little to no knowledge of biology, but I would really like to find out if it would be feasible to make such a system as a way of preventing infections. I ...