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Autoreceptors are receptors that are located presynaptically, on axon terminals that send negative feedback upon the actions of the neurotransmitter released from the axon terminal to prevent the further release of the neurotransmitter contained inside storage vesicles.

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Are all Autoreceptors Downregulated by their Respective Endogenous Ligands?

I know that the 5-HT1A and $\alpha$2 adrenoreceptors receptors serve as autoreceptors for serotonin (5-HT) and norepinephrine respectively and are down-regulated by repeat exposure to their respective ...