The use of methods from the physical sciences to aid in the study of biological systems.

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9
votes
2answers
2k views

Why is saltatory conduction faster than continuous conduction?

How does spacing apart sodium and potassium channels allow the action potential to travel faster down the axon? This is the reason always cited for saltatory conduction and myelination, but my mental ...
0
votes
1answer
56 views

How non-invasive blood glucose concentration measurement work?

Diabetes patients need to conduct the “fingerstick” a few times a day. One of the mechanisms of "fingerstick" is to take small amount of blood sample and put it onto a test strip. The enzyme on the ...
7
votes
3answers
108 views

Can a single axon propagate multiple simultaneous action potentials?

I have not been able to locate any research that indicates whether a single axon of a neuron or nerve cell can conduct multiple simultaneous (i.e. spatially separate) action potentials. I am aware ...
20
votes
1answer
540 views

How, on a physical level, does ATP confer energy?

When ATP is used as the energy currency to make, say, reaction X + Y → Z happen, is what happens on a physical level down at the molecular scale that during the reaction ATP + H2O → ADP + Pi ...
6
votes
4answers
253 views

Is human vision sensitive to frequency or wavelength?

In a vacuum, there is a one-to-one correspondence between light frequency ($\nu$) and wavelength ($\lambda$), ie. $\lambda=c/\nu$. But in a refractive medium, $\lambda=v/\nu$, so while the frequency ...
13
votes
2answers
917 views

Is the EC50 of an activating protein for an enzyme a good indicator for the binding affinity Kd?

We work with a membrane protein system where measuring the affinity between the enzyme and the upstream activating protein has been difficult, and when measured in detergent solution, it is almost 100 ...
5
votes
2answers
51 views

Problems understanding membrane potential

I understand that membrane potential is the difference of the extracellular and intracellular ionic charges, due to their concentrations. We say that the extracellular space has a charge of 0 and then ...
2
votes
1answer
453 views

What is the relationship between UV wavelength and penetration depth into human skin?

Some background - Some recent research has strongly suggested that UVA penetration into the skin is far more dangerous than UVB, a very good example is this paper by Agar et al. (2004). My query is, ...
2
votes
1answer
245 views

Are Bovine serum albumin, Avidin, Ficoll-70 and Dextran-70 positively charged or negatively charged? [closed]

Bovine serum albumin, Avidin, Ficoll-70 and Dextran-70,are they positively charged or negatively charged ? And which other solvents can be used as a substitute to water for preparing solutions in each ...
1
vote
1answer
136 views

How to manufacture different sized micelles in nano -scale?

I am trying to answer q5: "How can you manufacture micelles in A) nanometerer -scale B) and in ten nanometer -scale?" My Thinking Observations and some thinking Oil in ...