The study of the physiology and pathology of the heart and the cardiovascular system.

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Is there any range for Aortic Valve Gradient?

I understand aortic valve gradient is pressure on the value (measured in mmHg). What I would like to know is if there has been any research that identified a minimum and maximum pressure value as the ...
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11 views

reduced rate of blood flow and thrombus

How does reduced rate of blood flow cause thrombus formation? Although thrombus is usually caused due to hematoma (clotted blood mass). So, in this regard, we can say that due to thrombus formation ...
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9 views

ECG Atlases of Many Years?

I am looking for ECG data/atlases of Many years in healthy individuals of age from 6 to 40 years old. I would like to study several processes/effects occurring in years. Note the long-term ECG data ...
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25 views

Why are vegetations in Infective endocarditis common on the atrial side?

Robbin's Pathology says that vegetations of IE are more common on the atrial side in AV valves. In Liebmann Sack's Endocarditis, which is a sterile (non bacterial) type of endocarditis, the underside ...
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36 views

What is a lethal dose of THC?

With the oil form of THC being stronger then ever. What would happen if one was to take a stomach full of THC oil?
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5 views

How does the Sensitivity of Sokolev-Lyon indicators change by age?

I am studying the indicator and how diseases/age affect its sensitivity. However, no publication about it in PubMed and no luck in Escardio. How does the sensitivity of Sokolev-Lyon indicator ...
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8 views

Pathogenesis of Cardiac Atypia?

I am studying the pathogenesis of atypia in cardiac cells where the etiology is most commonly irritation or infection and where the precancerous risk depends on the context of diagnosis. This fact ...
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14 views

Electrocardiogram: Difference between Atrial Fibrillation and Atrial Flutter

I have been working on analyzing Electrocardiogram data. I have read several documents related to conditions of the Atria during fibrillation and flutter, the most lucid being that atria quiver with ...
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1answer
24 views

Electrocardiogram: Missed beats in presence of Ectopic beats or Premature Atrial/Ventricular Contraction beats

I have been working on analyzing Electrocardiogram data. So far, i have identified Ectopic beats and Premature Atrial/Ventricular Contraction beats. I am working on identifying Missed Beat in the ...
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27 views

Is 120/80 Blood Pressure at Lying position Notmal or high? [closed]

I was suffering from Anxiety and GAD for last 18 months. I used to have BP Shoot ups and it used to go till 170/105. Now I try to keep my mind Calm and I am trying to quit the medicine ...
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47 views

Average Beginning of Action Potential in ECG by t-f HRV

I have some ECG data where I am estimating the average beginning of the action potential. I am interested in the discrete Fourier analysis of joint t-f HRV when input data is ECG. Frequency domain ...
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7 views

Placental Adherence and Premature Heartbeat

I am studying the placental adherence in premature fetuses i.e. from 22nd week to 38th week of gestational age. About 60% of placental adherences are diagnosed during labour, which increases the risk ...
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23 views

What is the function of the Moderator band?

The moderator band in the right ventricle is a band sorts of muscle which consists of a significant branch of the AV bundle. Does it mean it delivers impulses to the anterior papillary muscle faster? ...
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24 views

Determination of Ageing by ECG inclusions/exclusions?

I am studying ageing and considering ECG signal because of its high sensitivity in theory (escardio). Some factors Sensitivity Gender Medical treatment ... Benchmark: RTG dental + wrist ...
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17 views

ECG Calibration by Infusion Pump?

I am trying to understand how to calibrate 5-lead ECG device with an infusion pump before the human calibration as described here. The system uses 5 electrodes (RA, RL, LA, LL and Chest). The monitor ...
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15 views

What is the realationship between arterial pressure and stroke volume

Frank-Starling Law says , When keep const Pvp (pulmonary venous pressure) and T ( heart period) and we increase Psa(aortic pressure or arterial pressure), Vd(end-diastolic volume) and Vr(residual ...
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83 views

Is it possible to consciously increase or decrease your own heart beat? [closed]

By doing yoga, can we manipulate our own heart beat? Is that possible for humans?
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1answer
70 views

Persistent HPV and CVD in Women?

Cardiovascular disease is the number one morbidity factor of women. I am studying the relationship between persistent HPV infection and CVD (Cardiovascular Disease) in inadequate immune responses. ...
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1answer
78 views

How are isovolumetric contraction and afterload related in the cardiac cycle?

In the cardiac cycle isovolumetric contraction occurs and causes a pressure gradient. The "afterload" is the pressure exerted on the ventricle from the artery. Is the afterload the cause of ...
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12 views

Membrane conductance in phase 1 of the cardiac action potential

Correct me if I am wrong, but in phase 1 of the cardiac action potential (for ventricle cells) there is flow of potassium ions due to the opening of transdent potassium channels. To me this would ...
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1answer
34 views

How are cardiac cells stimulated by an action potential?

Why, and how, does the action potential of one cell in the heart stimulate an action potential in the next cell? I'm interested in an answer with citation.
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41 views

What does the term pre potential mean in the pacemaker cells of the heart?

I recently read about the concept of the pacemaker potential in the heart . In this what does the term pre potential refer to ? Is it the same as the pacemaker potential. This is because one of the ...
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47 views

Why is there a structural difference between the bicuspid and tricuspid valve?

There are three cusps in the tricuspid valve and only two in the bicuspid valve? Why is there such a structural difference? Does it have anything to do with that there is oxygenated blood on the left ...
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5 views

How much potential from heart reaches the chest

I learn about the ECG waveform of heart potential.How much voltage will actually reach our skin which is developed in the heart(from Sinoatrial node).What will be the approximate voltage range when it ...
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87 views

Why do earthworms have 4 hearts?

I was reading about earthworms and came to know that they have 4 hearts. Why is there a need for a 4 heart system? What advantages would it have over a 1 heart circulatory system except for pumping ...
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71 views

Reasons for strange heart rate graph following exercise (line going up and down)?

Following a 2 minute general jumping and movement exercise designed to involve the entire body, the pulse was taken every minute for ten seconds. Strangely, the graph appears to jump up and down, for ...
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15 views

How can hyperplasia occur in non-fetal hypokinesis?

I have read that the hypoplasia can occur in fetal hypertrophic cardiomyocytes. However, I am interested if this can be theoretically be possible in non-fetal cardiomyocytes which are hypokinetic. I ...
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1answer
111 views

Why do changes in preload not cause changes in end systolic pressure?

I am trying to understand why changes in preload do not cause concomitant changes in end systolic pressure. If you have preload enhancement than this should lead to an increase in cardiac ...
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1answer
73 views

Is blood pressure in the aorta and brachial artery the same or different?

Does the blood pressure at the root of aorta equal the blood pressure in the brachial artery? I've heard it does, but it doesn't quite seem to make sense as I'd think the blood pressure would be ...
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61 views

Can bigger persons generally resist g-forces better?

I've seen a claim that bigger persons generally resist g-forces worse than smaller in an undergraduate biology book. However this claim was supported by the argument that blood has to travel a longer ...
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1answer
138 views

Cancer in myogenic heart cells? [duplicate]

Why cancer does not occur in myogenic heart cells? Is there any special ability in heart cells to resist cancer ?
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2answers
994 views

How does Bernoulli’s Principle apply to the cardiovascular system?

Below are graphs which illustrate the cross-sectional area, velocity, and fluid pressure through each vascular segment of the cardiovascular system. It makes sense that velocity and cross-sectional ...
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1answer
45 views

Physiology of tricuspid and bicuspid(mitral) valves

The tricuspid and bicuspid valves are atrioventricular valves. Both are valves that prevent backflow of blood pumped from the atria to the ventricles. However, the former has 3 "flaps" while the ...
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1answer
161 views

Does our heart stop when we sneeze?

Is it fact or myth that our heart stops beating for moments when we sneeze? If it is fact, what drives the heart to start beating again?
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191 views

How does amiodarone act as an alpha and beta blocker?

Amiodarone is potassium channel blocker but also voltage-gated Na+ channel blocker according to Pubchem. However, upon reading my notes I discovered Amiodarone blocks potassium channels and block ...
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1answer
16 views

What does this sentence about angina mean?

I do not understand this sentence Angina can be treated ambulatory (in out-patient) in stable angina. I think ambulatory refers to ambulatory ECG monitoring. So I understand this that you can ...
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1answer
379 views

Why is Electrical Cardioversion contraindicated in AF and Digitalis Poisoning?

I am thinking why electrical cardioversion is contraindicated in atrial fibrillation with digitalis toxicity/poisoning. Cardiac digitalis is also called digoxin and cardiac glycoside. It is ...
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1answer
36 views

Is missing Q wave characteristic for Wolff-Parkinson-White Syndrome?

No my study books says about that no Q waves in WPW syndrome. They are about wide QRS complex often however. I heard today that the characteristic property of WPW is often a missing Q wave, like here ...
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73 views

Is PTB ECG Diagnostic Database AAMI standard?

The PTB database can be found here. There has been only one publication about the database in the recent 15 years which list challenges in the database. You can review the ECGs (electrocardiogram) ...
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1answer
158 views

Explanation of ECG in MI using an electrostatic model

I found a paper presenting an electrostatic model to explain the ECG recorded in various leads. This model essentially calls for considering the depolarization wavefront to be the major contributing ...
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1answer
96 views

How can a heart of human work if one of its valve is not working?

Yesterday I went to a hospital and heard a doctor say that one of the heart valves of a patient is not working. However, the patient was still alive and was healthy; the patient could walk and talk ...
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173 views

Why can we control our breath rate but not our heart rate? [closed]

Even though we cannot survive for more than few minutes if we stop breathing or if our heart stops, why is it so that our heart beat is controlled involuntarily while breathing can be voluntarily ...
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1answer
1k views

How long do the periods of systole and diastole last?

The background to this is i'm doing some work using ECGs for an animation of the heart and i'm having trouble defining the end points of these periods, particularly diastole. Currently, the only ...
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1answer
75 views

What is the insight of Frank Starling law of the heart?

The Frank Starling law appears to be a trivial observation: stroke volume is directly related to the end diastolic volume In everyday language, as more blood fills the heart, the heart pumps more ...
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1answer
42 views

What causes a small bump in the arterial pressure plot?

In my book there is a plot of the arterial pressure against time. From the plot, during heart contraction, there is greater pressure on the artery and during heart relaxation, there is lower amount ...
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1answer
152 views

Similarity between a heart attack and a spasm

When someone is having a heart attack, could it be considered , in some situations, a spasm? Below, I have written how I believe the process may work. The heart is basically a muscle working ...
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275 views

Is the amount of blood that flows through every vein and artery per minute really a constant?

I was listening lectures from Mark Saltzman via Open Yale Courses. Now, if I did not understand him wrong, he said that the amount of blood that travels through every vein and artery in our bodies per ...
5
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1answer
148 views

Is hands-only CPR as effective as traditional CPR?

Is hands-only CPR as effective as traditional CPR ? Wouldn't 30 chest compressions + 2 rescue breaths be more effective if the person doesn't have a pulse AND not breathing? From my understanding ...
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1answer
475 views

Why do humans need a heart? [closed]

When I looked up the function of the heart, it says the heart pumps blood throughout the body. But the blood is already throughout the body, as it is recycled back to the heart. It is a chick-egg ...
5
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1answer
130 views

Normal ECG/EKG Measurement?

I'm getting started using ECG using a 3 lead system by iWorx. I have place the leads on my two wrists and the ground on my ankle and have recorded some data into the provided LabScribe 3 software ...