The study of the physiology and pathology of the cardiovascular system, especially the heart.

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What is the effect of persistent hypothermia on cardiac performance?

I define persistent hypothermia in this thread about the mechanisms of persistent hypothermia. The Graph of Katzung et al. in Pharmacology about Heart Failure: I am thinking which parts here are ...
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1answer
17 views

What is the insight of Frank Starling law of the heart?

The Frank Starling law appears to be a trivial observation: stroke volume is directly related to the end diastolic volume In everyday language, as more blood fills the heart, the heart pumps more ...
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45 views

How to measure Na/K channel activation at the membrane level?

Assume that there are two different signals occurring on the ECG - during depolarization and repolarization in the standard ECG. I was advised not to use the standard ECG in measuring the exact ...
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39 views

Effect of Aging on SA node's sympathetic fibers

I am trying to understand the effect of aging on the sympathetic fibers of SA node. I know that aging shifts the vagal curve to left in frequency due to aging. However, I am interested if aging has ...
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0answers
28 views

Normal ECG/EKG Measurement?

I'm getting started using ECG using a 3 lead system by iWorx. I have place the leads on my two wrists and the ground on my ankle and have recorded some data into the provided LabScribe 3 software ...
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0answers
27 views

Neural correlates of the function of the cardiovascular system?

Are there any known neural correlates of the function of the cardiovascular system? I'm looking for research results that use standard brain imaging techniques (e.g. electroencephalography, ...
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41 views

ECG of heart transplant patients

I am studying ECGs of heart transplant patients. The difficult thing is that there is so little available data publicly. I must apply for data in my universities. It would be also great if ...
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16 views

Public Pacemaker database online?

I am looking for any database about pacemakers with the leads atria A right ventricle VR left ventricle VL I did not find any in Physionet. Is there any anonymous data about different ...
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21 views

Recovering Coma patient with theoretical full knowledge of heart function

In coma, there is the medullary depression (stage of agony). Spontaneous respiration and circulation cease i.e. vasomotor center. There is no full circulatory and respiratory support. Assume you ...
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94 views

What is the nature of action potentials in autonomic nervous system?

My conjecture is that the natures of sympathetic and parasympathetic action potentials are different. My findings propose me that sympathetic action potential is little longer lasting than ...
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38 views

What are the mechanisms of disabling extrinsic control of heart?

I started this thread by thinking this question but I developed it further below What is the mechanism maintaining refractory period of pacemakers? My conjecture is that the mechanism is the ...
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37 views

How do the symptoms of Sepsis affect heart function?

I have intuition that Sepsis with infection can cause spastic functioning of heart during systole heart working spontaneously in snatches during systole atrial fibrillation first contraction of ...
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58 views

How do cellphones calculate heart rate?

How do cellphones calculate heart rate ? I understand that the cameras there try to count undulation in blood flow, but is the method of calculation same as that of professional SpO2 monitors ?
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60 views

To define the total Resistance of Systemic Blood Circulation

Some systems are in parallel. For instance, the resistance of lungs $R_{\text{lungs}}$. Assume here for simplicity that these parallel systems can be handled linearly. We also consider only Total ...
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79 views

Cardiac ECG database with high sampling rate?

MIT-BIT arrhythmia database follows AAMI standards. It has samples of 360 sampling frequency so it can detect heart beats of 180 Hz because of Nyquist frequency. I have noted that this frequency ...
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0answers
38 views

If a receptor is inhibited throughout embryogenesis, could there be observable phenotypic differences in the adult?

So I read a journal article entitled "Maternal hypoxia and caffeine exposure depress fetal CV function during primary organogenesis" (Momoi, et al., 2012) and in essence the article speaks of the ...
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0answers
44 views

Can we make any judgements about sleep or readiness to sleep from a heart rate metric and/or pulse oxymetry?

I'm looking at inexpensive and un-intrusive ways to quantify the state of human body/mind . One of these is Actigraphy, which is a study of human motion over time. This can be done with an iPhone ...
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10 views

Cardiology: What are the cause and effects of sympathetic stimulation to the heart

When fight or flight response is triggered, the sympathetic stimulation causes an increase in the muscle tension throughout the body and this increases the venous return to the heart. What is the ...
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44 views

Is the molecule nitric oxide responsible for healing blood vessels?

Is the molecule nitric oxide responsible for healing blood vessels? How does nitric oxide heal the blood vessels? I watched a documentary about the healing effects of nitric oxide. In the video I ...
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18 views

To Study Interactions of two molecules in PubChem

Assume you have two substances Diosminum / Hesperidinum. The former strengthens vascular walls. The latter has role in some glycoside biosynthesis. From Biochemistry, I recall that glycodises have ...
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12 views

Any databases with AAMI ECG and ECHO?

There is no AAMI 12-lead ECG databases available online. All of them have problems. I and my friends finally finalised our tests with St Petersburg. It is not AAMI. So the next step is to search ...
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52 views

How is Calcium regulated in myocardic AP and plateau phase?

The plateau phase is maintained by influx of calcium and outflux of potassium in the second stage: My conjecture is that calcium transforms between two phases ionated phase (free calcium from i/c ...
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13 views

To decrease the amount of proteins in the lymphatic drainage for short term

I am looking for some mechanism which can decrease the amount of proteins in the lymphatic drainage only for short term. Assume there is no flow between capillaries and lymphatic system because the ...
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31 views

Which reflex arcs work in Heart with extrasystoles?

I am researching what is triggering the extrasystoles - initial idea from this thread about Which ionic channels of Pacemakers can work in very low frequencies in extrasystole? I am interested in the ...