The study of the physiology and pathology of the cardiovascular system, especially the heart.

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Extremely rare occurence of Heart cancer?

The occurrence of Heart cancer (similar, but not the same as Rhabdomyosarcoma) is extremely rare, about 1 per year according to MayoClinic. The reason for this rarity is explained to be the ...
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3answers
258 views

How is the blood volume of a living organism measured without killing it?

How is the blood-volume of an organism measured without killing it? NOTE: The blood-volume of an organism is defined as the total volume of blood present inside that organism.
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633 views

Why do people say that trans fatty acids are bad for your health?

I've heard from several sources that trans FAs are bad for you and their consumption will lead to cardiac problems, and that they are indigestible. But I also learned from biochemistry that they are ...
9
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2answers
303 views

Does arterial blood always flow away from the heart?

Is there a negative net flow of blood in human arteries at any point of the cardiac cycle? I realise that blood flow can be turbulent, e.g. in the aorta or around stenotic arteries, but then the ...
8
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2k views

How does sodium in one's diet affect blood pressure?

Due to high blood pressure, my doctor has recommended I go on a low-sodium diet. So, that got me wondering what it is about sodium that drives this recommendation? What does sodium do to a body ...
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308 views

Why is blood pressure higher the more distal an artery is?

Why is blood pressure generally higher in more distal arteries?
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554 views

What effect does ambient temperature have on the cardiovascular system?

I am sorry if this is not appropriate for this site, but I think it fits so I am asking it here: I went for a run yesterday, and it was about -8 degrees Celsius. I was wearing a couple pairs of ...
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469 views

When to measure resting heart rate and blood pressure for following day-to-day trend?

I'd like monitor my resting heart rate and blood pressure to see how they are affected by regular cardiovascular training and other events in life. When should I take the measurements in order to ...
5
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1answer
521 views

Why does the heart use lipids (and not glucose)?

Fetal hearts use glucose as their primary metabolic substrate. Adult hearts use free fatty acids, which are less efficient (require more $O_2$ to synthesize the same amount of ATP); however, during ...
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202 views

How do insects such as crickets circulate blood through their antennae?

Some insects, like the crickets pictured below, have such slender antennae it seems no blood could fit. How do they get blood through their antennae?
4
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1answer
159 views

How quickly can the human heart rate rise and fall?

How quickly can the human heart rate rise and lower? For example lets say a human heart rate is rested and is at 60BPM and that person is suddenly scared to trigger their fight or flight reaction. ...
4
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1answer
52 views

What would life expectancy be in the western world in the absence of Ischemic heart disease?

In 2012, the leading cause of death was Ischemic Heart Disease. In 1st world countries, what is the life expectancy for people who do not die of Ischemic Heart Disease? I'm interested in the USA, ...
4
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156 views

intravenous (IV) in the tail vein of an anaesthetized mouse

I trained myself to do intravenous injection on live mice. However, on anaesthetized mice you don't see the flux of your product showing that your injection was successful. In the same way, on live ...
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1answer
138 views

Is a raised baseline between T and QRS normal in any ECG lead?

Here are excerpts from an unknown ECG lead. I find it weird that the "baseline" changes after the T wave and doesn't return until after the following QRS complex. Is that normal/expected for any lead? ...
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28 views

Calling for Free Online Data for Paediatric ECG?

I need free online data about heart murmurs to study these: heart murmur frequency , S2 heart sound frequency and its split, murmur timing, and duration, murmur intensity, S3 sound presence and ...
3
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1answer
61 views

Does the Heart Require Gold?

I distinctly remember an episode of NOVA from the early 1980’s that concerned itself with gold. One of the points that was made was that there are trace amounts of gold in the human body, ...
3
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1answer
102 views

Are ectopic beats considered sinus rhythm for pNN50 purposes?

One quantification of the heart rate variability of an ECG is pNNx, i.e. the proportion of consecutive NN distances that differ by at least 50 ms. When a premature beat occurs, the preceding and ...
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51 views

What percentage of human capillaries are located in the skin?

As in the subject line, what percentage of capillaries in a human (expressed in terms of total length, I suppose) are located in the skin, as opposed to internal organs? Google scholar has not turned ...
2
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1answer
247 views

What is the surface area of the human heart?

I heard that the human heart had a surface area of 1000 square feet, and I thought that that cannot be true. So what is the surface area of the human heart and what are the different ways it can be ...
2
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2answers
56 views

Breakdown current for human body

If I am not mistaken, during exposure to electricity sources it is the magnitude of the current and not the voltage that kills the human body. If so, what is the order of magnitude of current that ...
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1answer
183 views

Amount of neurons in the heart

Finding numbers for the amount of neurons in the brain is quite easy. Finding them for other human organs is harder. How many neurons are there in the human heart?
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1answer
37 views

Why there is a very high drop in pressure from arteries to arterioles?

Laplace law explains why the pressure is the same in aorta and arteries (100). I am thinking why there is so big drop in pressure when going from arteries to arterioles (40-60). Why there is a great ...
2
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1answer
403 views

fibroblast cells and fibers

I am interested in fibroblast cells in human arteries. Here are the things that I am not clear at the moment and I could not find any answer from the literature: What are the dimensions of these ...
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1answer
91 views

Why is elevated homocysteine considered a risk factor for angina?

Elevated homocysteine levels are listed among risk factors for angina. How is homocysteine related to the heart? Or the coronary arteries? How do these relationships make it a risk factor for angina? ...
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2answers
43 views

Can stress echocardiography show coronary blood flow difference before and after exercise?

Stress echocardiography means a pair of cardiac ultrasound imaging examinations, before and after exercise. I assume that coronary blood flow is increased after exercise. Is cardiac ultrasound ...
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2answers
551 views

Is it possible that the recipient of a heart transplant would display some of the donor's personality traits, as if the heart has memories?

I've read somewhere that after a person has a heart transplant, it is possible that his/her attitude, action or behavior would change slightly or significantly, as though he/she possesses some aspects ...
2
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1answer
706 views

How do inward rectifier potassium channels work in the heart?

Apparently in myocytes, there is an inward rectifier potassium channel that operates in phase 4 of the myocyte action potential. I have heard that while this is named as an inward rectifier, that ...
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1answer
325 views

Why is the blood pressure in the superior vena cava during inhalation less than during the exhalation?

For further investigation into the progress of the blood pressure, we will measure a patient's blood pressure in the superior vena cava measured during inhalation and during an exhalation. His heart ...
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47 views

Could below zero decibel environment cause arrhythmia?

While this topic has virtually no real life application and has never been examined due to obvious reasons, it is quite intriguing to me. I've read a lot of speculations and claims about the world's ...
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31 views

What is the correct medical procedure(s) for taking a resting heart rate?

Note: I thought the Biology stack exchange would suit this question better than the Fitness stack exchange. Please let me know in the comments if this is not suitable here. I am interested in ...
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38 views

Is this ventricular tachycardia?

I am investigating the public data of this. Its specification ...
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1answer
279 views

Valves in the heart

I am confused regarding the presence of valves in the superior vena cava. The superior vena cava does not possess valves unlike inferior vena cava, which possesses Eustachian Valve. Then where are ...
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29 views

In an open circulatory system, how is blood moved?

In the mollusks section, the powerpoint mentioned that gastropods and bivalves have an open circulatory system. According to the note, this means that the blood does not travel in vessels. How, then, ...
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50 views

Why are Lymphatic trunks part of the Cardiovascular system?

According to Wikipedia the Terminologia Anatomica (international anatomy standard) the lymphatic trunks are part of the cardiovascular system instead of the lymphoid system. Why did they make that ...
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1answer
97 views

Do nerve cells cause action potential in cardiac muscle?

I think the answer is no, but I am not 100% sure. If it was yes, then the dendrite of the nerve cell should each time receive a stimulus causing Na+ channels to open, when the contraction happen. ...
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52 views

What's seen when stress echocardiography shows ischaemia? Can this happen without angina?

What can be seen on the screen when stress echocardiography (a pair of heart ultrasounds before and after exercise) suggests ischaemia? Can this happen without chest pain? Illustration from ...
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9 views

Effect of Aging on SA node's sympathetic fibers

I am trying to understand the effect of aging on the sympathetic fibers of SA node. I know that aging shifts the vagal curve to left in frequency due to aging. However, I am interested if aging has ...
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44 views

How do cellphones calculate heart rate?

How do cellphones calculate heart rate ? I understand that the cameras there try to count undulation in blood flow, but is the method of calculation same as that of professional SpO2 monitors ?
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36 views

Why does the arch of aorta coils?

My study materials use the word vesselcompression chamber of aorta to emphasize aorta's elastic property. The arch of the aorta only coils, not its straight part. I think the reason why the arch ...
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24 views

Voltage-gated Potassium channels in the action potential of cardiomyocyte?

There is one type of potassium voltage-gated channels open in Phase 1 too. Some call them early repolarization channels. I am not convinced that the channels are different in different phases: 0, 2, ...
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1answer
46 views

Is end-systolic volume (ESV) the same as residual volume?

I am reading this site and my study materials. The end-systolic volume (ESV), 50-60 ml, is the volume of blood found in ventricles after systole and contraction of ventricles. I think ESV is the same ...
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27 views

Cardiac ECG database with high sampling rate?

MIT-BIT arrhythmia database follows AAMI standards. It has samples of 360 sampling frequency so it can detect heart beats of 180 Hz because of Nyquist frequency. I have noted that this frequency ...
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51 views

Sodium levels and blood pressure

Why does low $\ce{Na+}$ levels cause hypotension (low blood pressure). Alternatively, why does excessive intake of $\ce{Na+}$ cause hypertension or high blood pressure? From what I ...
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147 views

What affect does extra-cellular potassium concentration have on heart rate and conduction velocity?

If the extracellular potassium concentration surrounding a myocyte increases, then the potassium gradient accross the cell membrane decreases, and therefore the resting membrane potential will become ...
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31 views

If a receptor is inhibited throughout embryogenesis, could there be observable phenotypic differences in the adult?

So I read a journal article entitled "Maternal hypoxia and caffeine exposure depress fetal CV function during primary organogenesis" (Momoi, et al., 2012) and in essence the article speaks of the ...
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29 views

Can we make any judgements about sleep or readiness to sleep from a heart rate metric and/or pulse oxymetry?

I'm looking at inexpensive and un-intrusive ways to quantify the state of human body/mind . One of these is Actigraphy, which is a study of human motion over time. This can be done with an iPhone ...
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19 views

Is Sinus node conduction necessary for heart beating?

Assume a patient with previous cardial infaction which SA node not possible to activate action potential anymore. However, SA trying to beat unsuccessfully repeatedly waisting energy. Therefore, I ...
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1answer
32 views

Regional circulation and Cardiac output? [closed]

I am reading my study materials and think what is the systemic POV here Regional circulation Blood flow within the tissue/organs based on the functional demands of the tissue. E.g. The ...
0
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1answer
23 views

Can you approximate Cardiac Output by Ohm's law?

I found this sentence from my notes which I cannot understand PR < CO, CO $\uparrow$, PR > CO $\downarrow$ where ...
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1answer
13 views

Association of shorter telomeres with heart disease

From this paper Those with shorter telomeres in blood DNA had poorer survival, attributable in part to a 3.18-fold higher mortality rate from heart disease (95% CI 1(.)36-7.45, p=0.0079), and ...