The study of cells, their physiological properties, structure, environmental interaction, division, life cycle, and death, as well as the organelles they contain. Also known as cytology.

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220 views

Is there a karyotype database for human cell lines?

I'm looking for the karyotype of a specific cell line. Some karyotype are well known, such as HeLa or some carcinomas, but some are very hard to find, such as LG2 (B cells). Is there a database ...
2
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1answer
33 views

How does the drug MBC effect the depolymerization of microtubules in eukaryotic cells?

I have tried to look for the mechanism of how methyl benzimidazol-2-yl-carbamate affects microtubules in eukaryotes, but what I found wasn't very useful: Quilan et al 1980 assert that it acts by ...
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1answer
70 views

Can soap kill cockroaches and/or ants? If so, how? [duplicate]

Is it possible to use dishwashing soap as an alternative insecticide? How would that and what are the components of the dishwashing soap that would kill the insect?
0
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1answer
41 views

What's the mixture of plasma and haemoglobin called [closed]

I know of oxyhaemoglobin but the mixture of plasma and haemoglobin in the blood gives what?
0
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1answer
52 views

What's the mixture of carbon and haemoglobin called [closed]

I know of oxyhaemogloblin , the mixture of oxygen and haemoglobin , but carbon and haemoglobin combination is what's confusing
13
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1answer
867 views

Can an organism exist as a single cell but come together as multi-cellular during certain times?

I am trying to remember a particular segment from a BBC special, in which there was single cellular species. However, at certain times all the individual cells came together to form a structure, not ...
2
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1answer
39 views

Is there some research paper which focus on the influence of using cancer cell as experimental materials on experimental result? [closed]

Cancer cell is unstable cell and high variation, but there are many experiment use cancer cell as experimental materials. I always wonder how much influence can using cancer cell as experimental ...
0
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0answers
40 views

What is plectonemic coiling? When does it uncoil?

Is it the inseparable coiling of two double stranded helices (each representing a chromatid)? In early prophase the chromosome appear as coiled filaments but in late prophase each chromosome has two ...
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0answers
23 views

is there any relationship between shape of the nucleus and the function of the cell?

is there any relationship between the shape of the nucleus and the function of the cell, like in the case of leukocytes, all of them have different shapes.
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0answers
45 views

What’s wrong with a shriveled cell?

When you place a cell into a hypotonic solution, water rushes into it and it bursts/lyses. Thus, the cell dies. However, when you place a cell into a hypertonic solution, water rushes out of it and ...
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1answer
12 views
4
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1answer
92 views

Why it seems that principles of chemistry are not being applied in this biochemical process? [closed]

According to an answer in this question, my concept used below does not apply: In the non-cyclic photophosphorylation, consider splitting of two water molecules, then 4 e- (electrons) and 4 H+ ...
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0answers
11 views

Function of NEZHA gene [closed]

What is the function of NEZHA? What effect does it have on microtubules and PLEKHA7? What happens after it has been knocked down?
0
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1answer
38 views

Converting miRNA names

I need to convert all of my microRNA names e.g. hsa-miR-30e-5p to e.g. entrez gene IDs, ensemble IDs or another ID. Does anyone know a good ID conversion tool for microRNAs? (I managed to convert it ...
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2answers
58 views

Structure of Cell

Are cells spheres or ovals/circles bound by phospholipidbilayer? If they are spherical how are we able to see the nucleus through the phospholipid bilayer under a microscope?
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0answers
25 views

mRNA extraction from mice ears.

I am trying to extract RNA from mice ears and for some reason I don't have RNA when I perform the electrophoresis. I directly cut the ears and I put it in a tube with a bead and trizol. then I place ...
5
votes
1answer
2k views

What is our skin made up of?

Again, it is a basic question. What is our skin made up of? is it made up of many cells arranged in a systematic way or is it just like any layer say of a book?? what is the difference? where is the ...
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0answers
33 views

Can the activity of bacteria be influenced by magnetism? [closed]

Some organisms are tuning their direction on a magnetic field. But are bacteria also reacting on magnetic fields and can it be used in health therapie as a kind of 'antibiotic'?
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1answer
99 views

What causes swelling after impact?

Why does the head swell after getting hit by something hard? What is the liquid that forms after impact?
0
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0answers
110 views

Why did multicellular organisms evolve when a single cell can survive on its own? [duplicate]

Since unicellular organisms can survive, why would there be evolution of multicellular organisms?
3
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1answer
65 views

What do proton pump inhibitors do?

I know that sodium azide and 2,4-DNPH inhibit proton pumps. The azide is called an inhibitor and 2,4-DNP is called uncoupler. I want to know what's the difference between the mechanisms of action of ...
0
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1answer
42 views

Normal cell diffusion in normal organism?

We know, that cancer cell can travel across an organism. Is this ABSOLUTELY impossible for NORMAL cells? For example, is it EXACTLY ZERO probability to find some bone cells inside liver or some skin ...
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1answer
53 views

Why did eukaryotic cells develop? [closed]

If eukaryotic cells can survive in extreme conditions, then why are their still prokaryotic organisms?
3
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1answer
63 views

Could a single cell be brought to life?

If a scientist is observing a single cell under a microscope, and then realizes that the cell has died, is it possible to bring that dead cell back to life? For my inquiry, let's assume that the ...
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0answers
30 views

Is it possible to make the human cells totipotent? [closed]

we all know humans are not capable of regenerating from a single cell. Is there any possibility that we can make cells totipotent?
2
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1answer
59 views

ADCs: by what mechanism are antibodies internalised [closed]

I read that ADCs (Antibody-Drug Conjugates) act by a -mab for a particular target being bonded to a cytotoxic compound. From my high-school-with-crayons knowledge of antibodies, however, one part of ...
1
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0answers
33 views

Bacteria surviving a β-lactam antibiotic

What changes can occur in the cell wall of a bacteria for it to survive a β-lactam antibiotic? I think that because a bacteria possesses peptidoglycan in its cell wall, they are β-lactam sensitive, ...
0
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0answers
21 views

What percent of cells are lysed when I make my smoothie?

This is an entirely irreverent question, but it does concern biology. I'm a physicist by training so I like to be able to estimate order of magnitude. I made a smoothie the other day with milk, ...
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2answers
219 views

Growth factors vs. mitogens

According to Campbell Biology, A growth factor is a protein released by certain cells that stimulates other cells to divide. and according to Wikipedia, A mitogen is a chemical substance ...
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2answers
149 views

Density of cells in human tissues?

Where can I find values, or estimates, of the density of cells in human tissues? Maybe an overall estimate, or distinct values for distinct tissues? Or maybe not human, but mammal tissues (which ...
2
votes
1answer
659 views

Difference between protein channels, protein carriers and protein pumps?

I'm revising for my biology exam and I don't fully comprehend the difference between protein channels, carriers and pumps. I know that: Protein channels do not require ATP (passive transport) The ...
3
votes
2answers
288 views

How many centrioles/basal bodies are there in multi-ciliated cells throughout the cell cycle?

I thought there were only two centrioles per cell, that convert to the basal body at some point during the cell cycle. I also thought there's one basal body per cilium, so I'm not clear on where the ...
3
votes
1answer
134 views

HOw are AMP's “recharged” to become ATP's in a cell?

I understand that after the translation stage of ribosomal protein synthesis, tRNA molecules are floating in the cytoplasm without attached amino acids until they find the correct aminoacyl tRNA ...
2
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1answer
85 views

Which step in endocytosis requires ATP?

Everybody seems to agree that endocytosis is an energy-using process, and as such requires ATP hydrolysis. However, which particular step requires it? More precisely, which 'molecular machine' ...
1
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1answer
58 views

How difficult is it to make a shRNA/miRNA/siRNA to silence/knockdown NaV1.7 voltage gated sodium channels in humans?

There have been various research projects that experimented with shRNA/miRNA/siRNA to specifically silence/knockdown NaV1.7 voltage gated sodium channels in small animals like rats & guinea pigs. ...
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12 views

Do you know of any scratch assay video databases?

It would be of great help for a statistical work we have been asked to carry out at our University. Thank you very much in advance.
1
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1answer
53 views

Do snRNAs exit the nucleus or not?

In Molecular Biology of The Cell (Alberts, et al., 2015), it lists the various RNAs that are trafficked through the Nuclear Pore Complex (NPC) into the cytoplasm. The list includes snRNAs, but I ...
6
votes
2answers
240 views

At any given moment, how much energy is stored in the human body as ATP?

At any given moment, approximately how much energy is stored in the human body as ATP in the ADP-P-bond? This of course depends on what type of cell it is and the activity of the individual in ...
3
votes
1answer
60 views

Can a cell start a mitosis if it lacks energy or molecules to complete it?

I'm wondering whether a cell can start a mitosis if it lack molecules or energy to fully complete it. From what I'm reading on wikipedia the cell passes most of its time in the interphase in which the ...
3
votes
1answer
40 views

What is the purpose of requiring two separate binding systems for the antibody response?

I've read that in most cases, B-cell activation requires helper T-cells. This requires antigen binding by both antibodies and T-cell receptors, using two different antigen-binding proteins, ...
1
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2answers
47 views

At which end does polymerization of microtubules occur?

My book says that polymerization and depolumerization of microtubules occurs on the + end however, I've found a note that says that depolymerization occurs on the - end. I need help please :) thank ...
4
votes
1answer
50 views

Is HSV-vector-mediated miRNA expression in dorsal root ganglia stable?

My question is on the following article: "Reduction of voltage gated sodium channel protein in DRG by vector mediated miRNA reduces pain in rats with painful diabetic neuropathy" My question is, do ...
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0answers
26 views

Effects of pH vs membrane potential within a cell? [closed]

How are these two concepts related? Does changing each result in the same effects? As in: what kind of reactions/processes would be affected if we changed the pH within a cell? Would the results ...
1
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2answers
83 views

In cell division, are daughter cells identical?

I understand that after a cell replicates, there will be two daughter cells instead of one. But wouldn't one of them be the old cell that created the second one? The old cell having gone through G0, ...
5
votes
1answer
31 views

Constant or variable number of chiasmata during recombination?

During recombination, is the number of chiasmata consistent for each gamete and are the chiasmata regions consistent within a single organism?
1
vote
1answer
164 views

Do human somatic cells have 46 chromosomes all the time?

As far as I know, a human somatic cell has the cell cycle: Interphase and Replication (mitosis). In interphase the cell has 2 growth phases (G1 + G2) and a synthesis one (S phase being in between G1 ...
0
votes
0answers
18 views

How sorbitol treatment selects ring stage of plasmodium falciparum

I would like to know the basic chemistry behind ring stage selection by sorbitol. Sorbitol is used for Synchronising the plasmodium culture in ring stage. How the chemical retains or selects ring ...
1
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1answer
54 views

Are nucleotides at the ends of DNA stripped on aging?

I had the following understanding (now after reading a popular science article seeming wrong understanding): DNA in (regular) cells (in human and some other organisms) are protected by telomers. ...
1
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1answer
46 views

cell specialisation and their location

When we create new cells, how come they are of the 'right' type at the 'right' place? For example, when I make a new cell on my lips, it's obviously not the same as a new one in my kidneys. Is the ...