The study of cells, their physiological properties, structure, environmental interaction, division, life cycle, and death, as well as the organelles they contain. Also known as cytology.

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17 views

Ions in different cell compartments

I would like to understand the distribution of metal ion concentrations (such as Mg2+) in the different cell compartments. I tried very hard but still couldn't find such information. Could anyone help?...
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66 views

Which steps occur in each phase of Meiosis and Mitosis [closed]

MITOSIS In mitosis am I correct in saying that the spindles attach to the centromeres at the end of prophase/prometaphase? (I read this in an answer to another question) MEIOSIS Does the ...
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1answer
51 views

Why only mitochondria and plastids?

Why are there only two unique semi-independent organelles? Why are there no others, symbiogenesis seems like it should be a relatively common thing. So do most organelles just lose all their DNA? Or ...
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1answer
106 views

In the video, “Inner Life of a Cell”, what's the empty space between the molecules?

In the video, "Inner Life of a Cell" there's a lot of empty space between the proteins. Is it just a simplification (i.e. they omit smaller molecules)? If so, what are the smaller molecules supposed ...
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1answer
36 views

How chameleons change color? [closed]

Well, I was watching a video about chameleons and I saw that their cells can change color. Can someone explain me how is this possible?
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1answer
102 views

What determines whether the maternal or paternal allele is expressed?

I am taking cell biology and have this question: During the process of gene expression, it is possible to express either the maternal allele or the paternal allele. When and how is the determination ...
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1answer
63 views

What are allogametes? please explain [closed]

Allo means different or unrelated I guess.Please clear me the meaning with some examples.
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1answer
82 views

Are surface area or volume conserved during cell division?

I am a student of physics of mathematics with very little knowledge of biology. Nevertheless, I am very keen on biophysics and I'm trying to learn the biological concepts that I need on the way. I'm ...
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1answer
835 views

Difference between protein channels, protein carriers and protein pumps?

I'm revising for my biology exam and I don't fully comprehend the difference between protein channels, carriers and pumps. I know that: Protein channels do not require ATP (passive transport) The ...
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25 views

Degenerate primer designing software

Can any one provide online free degenerate primer designing software. I have tried couple of them like CODEHOP is one where BLOCK formatting step finding difficulty, can anyone help me out....
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1answer
73 views

Reseach on feeling pain of other people

I'm more of a tech than bio kind of guy, but I have read and learned a lot alongside of my girlfriend's education. Which is very interesting!! Currently I want to investigate : people claiming to ...
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1answer
34 views

Where exactly is 'Colloid' with regards to synthesis of thyroid hormones?

I've researched colloid and it seems to be a substance of microfibres and thin films in which thyroid hormones may be synthesised, but I was wondering where this exactly is... I think it could be in ...
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1answer
46 views

Lysosome function [closed]

Does any cell have lysosomes in it? Or maybe there are other organelles that do the same function. I read about it a lot and I can't find a good answer.
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35 views

How do cell repair mechanism ratios change as they age?

I have seen that embryonic stem cells are shown to use homologous repair for double strand breaks rather then non-homologous end joining (NHEJ). [1] I am wondering if something also happens to a cell'...
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2answers
622 views

Mitosis versus Meiosis I: What's the difference?

At the end of mitosis, one cell has divided into two diploid cells. But at the end of meiosis I, there are two haploid cells. How are the two processes different to produce these two types of cells?
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1answer
236 views

Reason for the source of fetal bovine serum

What is the reason that perhaps the most commonly used serum in labs is fetal bovine derived? Is there something about fetal serum that is particularly useful over say serum just harvested ...
3
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0answers
57 views

Is it possible to isolate cells harboring a specific DNA sequence?

Suppose on cell subpopulation harbours within its genome a specific DNA sequence that do not exist in other cell subpopulations. Is it technically possible to isolate such subpopulation ? and if yes, ...
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1answer
58 views

Cellulose - why is it fibrous and not granular?

I was reading a book where it said that the 1 - 4 Glycosidic bond of the Beta Glucose meant that cellulose is fibrous and not ...
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1answer
55 views

Which organs need to have fluid compartments in order to develop properly?

I am a student, slightly struggling with the new concept of fluid compartments. I know that there are two main types of fluid compartment, extra and intracellular fluid. I also read that most organs ...
2
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1answer
118 views

How does the pancreatic beta-cell know how much insulin to secrete in response to glucose?

How do $\ce\beta$-cells know how much glucose is in the blood? I know that when glucose enters a beta cell it triggers the cell to produce insulin. $\ce\beta$-cells trap glucose by converting it into ...
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1answer
36 views

What effect is seen when the extracellular concentration of sodium is increased? [closed]

I can't seem to figure out how this would effect the cell since sodium is not very permeable.
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18 views

Amputation of part of the cytoplasm of the amoeba? [closed]

We ampute a part of the cytoplasm of the amoeba many times and we observe that amoeba is not divided This experience allows to deduce the cause of the division of amoeba Do that have relation with ...
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1answer
150 views

Is a nucleus more dense than the rest of the cell?

On the one hand, it seems like there's a higher density of 'stuff' in a nucleus, so it should be more dense. On the other hand, if it was more dense, I'd imagine that nuclei would 'settle' to the ...
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1answer
134 views

If so many different hormones/molecules work by activating adenylyl cyclase, how do they have different effects?

It seems that many hormones and molecules work by activating adenylyl cyclase to convert $\text{ATP}$ to $\text{cAMP}$, such as adrenaline and glucagon. Both of these seem to bind to $\text G$ protein ...
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1answer
78 views

Hayflick limit and hair or nails

I am not a bio major but I have heard about Telomerese shortening in each cell division which leads aging and cellular death. I also read that Hayflick limit is about the number of divisions a cell ...
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1answer
43 views

How DNA programs the first cell in womb into a human [closed]

Sorry if you see me silly. I am just a programmer happens to be curious about biology... So far I understand how DNA make protein, how cell divides, how one composed of cells->tissues-> organs. But,...
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24 views

Pathogenesis of type IV hypersensitivity

In hypersensitivity, as I understand it, a normal immune response gets excessive, misdirected or wrongly regulated to cause tissue injury. The various types determine the various ways in which the ...
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1answer
77 views

Is the problem of cryonics only the pressure?

According to the pop-sci sources which I drew on from, the only problem with freezing whole bodies its that you can't conserve it without freeze-damage. If you were keeping a cold-blooded animal in a ...
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1answer
72 views

Are there differences in energy of glucose isomers?

There are many isomers of glucose, including galactose and fructose. Do they have different chemical energy levels, and why? What makes galactose and fructose useful compared to glucose, and would ...
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0answers
23 views

Could drugs promoting angiogenesis be used as a treatment for burn victims?

From what I've learned from my textbooks and in class lecutures it seems that inducing angiogenesis for people with severe burns would be an excellent way to speed up the healing process. Is this ...
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1answer
46 views

Why is Bcl2 a good target for cancer therapy?

Bcl2 is a family of proteins that are involved in the inhibition of apoptosis in cells. My question is that what makes this anti-apoptotic protein useful in cancer therapies as opposed to focusing on ...
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1answer
35 views

why dna polymerase 3 requires a primer for replication [duplicate]

Why DNA polymerase 3 needs a primer to star replication.And whats happens when there is no AUG sequence on entire DNA.
2
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1answer
36 views

How are cardiac cells stimulated by an action potential?

Why, and how, does the action potential of one cell in the heart stimulate an action potential in the next cell? I'm interested in an answer with citation.
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17 views

Arginine finger for regulating GTPase activity of heterotrimeric G-proteins as well?

I've seen video on iBiology discussing mechanism of Ras-Gap protein regulation of Ras protein (monomeric G-protein) involving an "arginine finger' from Ras-Gap for stabilization of intermediate in ...
3
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1answer
49 views

Why does a cell produce a lot of p53 protein only to later degrade it?

It is known that the half life of p53 is short and so does that play a role in the amount of energy the cell would need to expend to degrade all the p53? By that does the fact that the half life of ...
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32 views

Why don't the minus ends of microtubules shrink?

Is this because $\alpha$-tubulin is always in the GTP state? Or is it because $\gamma$-TuRC stabilizes the minus end?
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2answers
132 views

Question about proto-oncogenes and oncogenes?

My textbook says: Growth-promoting genes are called proto-oncogenes. Some can be changed into oncogenes by a point mutation that alters the ability of the proto-oncogene to be switched off. They ...
3
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2answers
64 views

Are the ribosomes specific for each organism

If we removed one ribosome from human and we put it inside horse, would the ribosome perform the as it would in humans or it will not work or somewhere inbetween?
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1answer
77 views

Is there any way to make protein pass through cell membrane?

Protein cannot pass cell membrane because it's a large molecule. Until now, is there any technique that can make protein pass through the cell membrane in vivo? I want to create a protein-drug that ...
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1answer
282 views

Why do specifically bananas go brown quicker in the fridge?

Perhaps the title should be: Why don't all fruits containing phenol residues go brown quickly when left in the fridge? Bananas go brown over time because of the oxidation of phenol residues. ...
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1answer
45 views

What does uniprot consider “unambiguous” evidence for the subcellular domain of a protein?

Uniprot has annotation for subcellular location of protein domains. This topological domain information of proteins is under the TOPO_DOM flag. In most cases the ...
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3answers
238 views

Can/Have cancer cells be/been used in stem cell culture lines?

Since Cancer cells have unlimited growth potential, can they be induced towards totipotency and pluripotency? If so, can cancer cells be used in stem cell culture because of similar properties of ...
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1answer
119 views

What's the difference between tumor cells and host cells? [closed]

When you talk about cancer, is there a difference between tumor cells and host cells ? What is the role of immune cells ? in a nutshell ?
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46 views

Mechanism of Octoxynol-10 as a preservative in vaccines

I noticed that the Fluarix Quad flu shot this season contains Octoxynol-10 rather than Thimerosal as a preservative. I am not expert in this area, so I did a Google search of "Octoxynol-10", and ...
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0answers
40 views

How do human cells respond to mechanical pressure such as heel contact during walking?

Basically, I'd like to do a full accounting (inventory, assets, liabilities) of a human cell under mechanical pressure. For example, if in steady-state, does the cell consume more or less energy ...
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0answers
15 views

Heteroplasmy in different tissues

I have only started reading the substantial body of research on heteroplasmy. I was curious if anyone knew of attempts to measure the somatic cell mtDNA mutation rate, to see if it differed from the ...
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35 views

What does high CD4 level means?

I was going through this webpage and I found the following lines: We hypothesised that despite unimodal distribution of CD4 co-receptor on naïve CD4 T cells they are not homogenous in their ...
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38 views

UACC-462 cell culture

UACC-462 is a pancreatic cell line established in the University of Arizona Cancer Center (UACC). The cells are available from ATCC and there is the instruction for culturing UACC-462. M-41 medium. ...
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23 views

What is the significance of 9+2 arrangement in flagella?

Why eukaryotic flagella have 9+2 arrangement .? What is the significance? a 9+0 flagella should have worked the same way .
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1answer
93 views

Why do eggs lack an endoplasmic reticulum?

Trueman's Elementary Biology book I found says that the endoplasmic reticulum is absent in eggs, but no reason is given. Why is it absent?