The study of cells: their physiological properties, structure, environmental interaction, division, life cycle, and death, as well as the organelles they contain. Also known as cytology.

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Database of Multicellular and Unicellular organisms?

I'm trying to annotate a list of organisms taken from NCBI for cellularity (unicellular or multicellular). Does any of you ever found a database with association between an organisms' name or taxa and ...
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27 views

What are the effect of microtubule or microfilament inhibition on yeast expression profile?

I was wondering whether anyone has looked at what are the expression changes in yeast when the microtubule or the microfilament polymerization is inhibited? Have there been whole-genome studies?
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307 views

How much does the Hayflick limit/telomere length vary across taxa and within humans?

Since they seem to be quite connected, I'm curious if anyone knows of research comparing the Hayflick limit (and presumably by extension telomere length) between different taxa. I've heard the ...
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62 views

Missing cells from immunopanning

Why do I not have any cells left in my positive panning plate after transferring from the negative panning plate during immunopanning? I am trying to purify retinal ganglion cells from postnatal rats ...
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308 views

Effects of exercise on the brain

I am well aware of the phenomenon of neurogenesis induced by exercise, as well as the dopamine release that results from exercise. I am really interested in neuropsychology and the effects of exercise ...
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57 views

Cell cycle selection

Is it possible to select from colonies only cells which are at a certain stage in the cell cycle? E.g. if I was trying to analyse expression of a number of genes during different stages of the cell ...
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37 views

What is the difference between organelle membranes?

Cells and organelles are contained in lipid bilayers. I'm particularly interested in eukaryotic organelle bilayers and the biophysicochemical differences between them. Many papers assume a ...
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29 views

What metabolically happens when an egg fuses with the nucleus of a somatic cell

In stem cell biology, it is recognized that embryonic stem cells are transcriptionally inactive for the first 3 days of development. However, during somatic cell nuclear transfer, the nucleus is ...
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why do some cells in the body prefer necrosis to apoptosis as a means of cell death?

There are many programmed cell death pathways, but some cells show a greater preference for some over the other. I'm wondering as to why if necrosis is an inflammatory response that causes damage to ...
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131 views

Stardust or the elements in our bodies

How do we know we are made of stardust? As our cells divide, are our atoms repurposed from existing materials or spontaneously generated? Do we consume materials after we are born that contain ...
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264 views

How do we look inside the cell?

My sister is in 9th grade biology and her teacher avoided answering the question of how we actually study the inside of a cell. I haven't taken biology in a while but I'd like to give her an answer. ...
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157 views

Number of genes required to sustain life

Are there estimates of the minimum number of genes required to sustain life? In what I mean by life here, I don't include viruses.
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81 views

Cancer growth and cell division [closed]

I am confused about the prerequisites for cell division and cancer. Which of the following is necessary for the cell cycle to progress? Hormones Growth factor Cyclins Cyclin dependent kinases ...
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2k views

Cell life: division for immortality or reproduction with aging

Are the two cells that are derived from one cell, ‘twin sisters’ or a ‘mother and a daughter’? In other words, can a cell really be divided to live an "immortal" life or is cell reproduction the ...
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Are there verbs for “undergo mitosis” and “undergo meiosis”?

From my experience on SE sites, I believe this is the right site to ask this question under "terminology". I've been trying to find out whether English has one-word verbs for "undergo mitosis" and ...
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54 views

What effects does being cryogenically frozen have on a person's body? [closed]

I'm wondering what effects are known to happen to a person's cells when a person is cryogenically frozen, especially those that need to be overcome in order to "bring them back to life." From a ...
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41 views

Concentration dependent cellular processes

Are there any famous biological processes that depend strongly on a chemical concentration reaching a particular value, like some sort of switch? E.g. if concentration of chemical x reaches ...
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54 views

Significance of lipids in biological membranes…?

Membranes are specifically designed by lipids to maintain internal hydrophilic environment in narrow range.There are hydrophobic amino acids among naturally occurring 20 amino acids and as well as ...
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48 views

Where can I find a full genealogy of human cell types?

It is said on Wikipedia, that the precursor of blastocyst is a morula, and that the precursor of morula is a zygote. This gives us the part of genealogy tree of cell types. Unfortunately, no full ...
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108 views

Connect the inner and outer space of cell with a wire, will there be electricity?

There is a potential difference, but ions can not go through wires, right? Though there is a electric field, but there is no electron source, I am thinking the answer is no, or will there be some ...
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95 views

What are the different, high-level programs along which a eukaryotic animal cell can follow?

What are the different, high-level, disjunct (mutually exclusive at one particular point in time) programs or pathways along which a eukaryotic animal cell can follow? Examples of programs would ...
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783 views

How long can a unicellular organism live without nutrition? What happens after that? Does it depend on the domain?

Say I have three unicellular organisms: a eukariote, a bacterium and an archaeon. If I cut off nutrition from them at the same time, how long will it take for them to die? What will their death look ...
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106 views

Which of the two mitochondorial membranes relate to bacteria according to the endosymbiotic theory?

I seached for endosymbiotic theory in Wiki and I found this about endosymbiotic theory: Symbiogenesis, or endosymbiotic theory, is an evolutionary theory which explains the origin of eukaryotic ...
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62 views

Has an artificial symbiotic relationship ever been created?

Have 2 organisms ever been introduced to create a symbiotic relationship that doesn't occur in their natural environment?
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23 views

Polarized epithelium and localization of ion channels

I'm trying to learn more about polarized epithelial cells of the gut. I am familiar with classic brush border transporters localized to the apical memebrane to facilitate nutrient absorption. I am ...
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78 views

Amino acid profile of GPCRs

You are studying cellular signalling through a newly identified GPCR. Specifically you’re working on a pair of newly identified GPCRs, GPCR-A and GPCR-B. Each binds the same small ligand, but ...
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180 views

Benefits of CLARITY?

What are the benefits of CLARITY over this technique that was published more than a year earlier? Of course the second technique needs a fancier microscope that is likely more expensive and requires ...
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140 views

Why are centrioles aligned at 90 degree with each other?

The centrioles are aligned at 90 degree with each other. What is the function of this?
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130 views

How do different tissue culture matrices affect background in fluorescent microscopy?

In response to my previous question, I've been reading up a little bit on poly-D-lysine, Collagen I, Collagen IV, laminin, and other tissue culture coatings that promote cell adhesion. I've always ...
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176 views

What molecular processes are involved in pseudopodial extension?

I am curious as to the processes and mechanisms involved in the extension of pseudopodia in amoeba. How does the cell know and control the direction and extent of pseudopodia formation at a molecular ...
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11k views

What type of cell do you start with in Meiosis?

Okay, I was learning about mitosis and meiosis in school and had a question. I know in Mitosis you first start off with a Diploid (2N) cell and then end up with two ...
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756 views

“Acellular” designation for organisms

Why do some biologists refer to single-celled organisms such as Amoeba and Paramecium as acellular (i.e., without cells) rather than unicellular (i.e., one cell)?
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28 views

Detailed mechanism of the cause of diabetes mellitus type 1?

I have read in some texts that diabetes mellitus type 1 is caused by degeneration of beta cells due to our body's own immune reaction.Is it true? Can you explain further how are such types of immune ...
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38 views

How does one determine intracellular concentration?

The TL;DR version Is there a fast way to determine what the cell environment of a particular cell (E.g RBC) is? (in terms of solute/ionic concentration) I'm not sure if the question belongs here, ...
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1answer
109 views

Integration of several environmental signals

I am looking for examples of different functions that are good fit to how signals are computed in order to respond to the environment. Let's make my question more copmrehensible with an example... ...
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1answer
42 views

SEREX serological analysis of cDNA expression library

What is Serological Analysis of cDNA expression library? I went through this article:http://cancerimmunity.org/serex/introduction/ but could not really make out. Can someone please explain this to me ...
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51 views

How much of the jejunum is bypassed during gastric bypass?

There is both long and short limb bypass surgeries. I want to know how much of the jejunum is bypassed with each procedure.
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48 views

How do mosquitoes maintain telomere length?

While the vast majority of eukaryotic organisms maintain their chromosome ends (telomeres) via telomerase, an enzyme system that generates short, tandem repeats on the ends of chromosomes, other ...
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300 views

which exact mechanism triggers the first cell differentiation after n divisions?

I would like to understand which mechanism triggers the first cell differentiation after n divisions. I read previous articles on SE and Wikipedia articles on cellular differentiation and ...
3
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1answer
158 views

What is range of the number of individual organelles in cells

What is the range of the number of individual organelles in a cell? I am not a biologist but I understand that there's one nucleus and sometimes lots of mitochondria, so I am after the total number. ...
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175 views

Does an allergic reaction kill body cells?

I have wondered what actually happens in an allergic reaction that causes the symptoms such as pain, rash etc. Is it possible that the human body actually kills its own cells in the process?
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29 views

Estimating RPM to RCF in Methods from Older Papers

I'm attempting to replicate a cell biology method from a 1958 Laboratory Investigation paper. The protocol is for the isolation of an extracellular matrix protein, and a key step is a centrifugation ...
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1answer
42 views

Prevent biofilm formation on moist surfaces

I have an indoor fountain with lots of water. What are the most common microorganisms in this kind of moist environment, and what are the standard way to prevent biofilm formation by them? I thought ...
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1answer
57 views

PSI-BLAST website algorithm parameters

http://blast.ncbi.nlm.nih.gov/Blast.cgi In this website, when I want to apply the psi-blast algorithm on a sequence, under the section of algorithm parameters , what does PSI-BLAST threshold mean? ...
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55 views

How is the growth of benign tumors suppressed?

A benign tumor has an outer layer of cancerous cells beyond which are regular cells (I Think). The Tumor must have some kind of boundary layer like a wall where somehow the cancerous cells can't ...
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121 views

How many centrioles/basal bodies are there in multi-ciliated cells throughout the cell cycle?

I thought there were only two centrioles per cell, that convert to the basal body at some point during the cell cycle. I also thought there's one basal body per cilium, so I'm not clear on where the ...
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67 views

What's a replicate line?

The methods section inside a paper I'm reading make mention of replicate lines. Example: "We founded 10 replicate lines from a single clone". This is in the context of experimental evolution and ...
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1answer
854 views

How does sugar enter neurons if they don't use insulin?

I heard somewhere that as opposed to other cells, neurons do not use insulin to get their sugar supply. Why is that? What is the alternative mechanism? I assume sugar can't just enter the cell ...
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1answer
386 views

Are there records of monozygotic twins in which one experiences androgen insensitivity syndrome

I have given my high school biology students the thought experiment of "What would happen if a researcher induced twinning of a female zygote and then replaced one of the X Chromosomes with a copy of ...
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185 views

Why is most tissue cellular?

Most tissue is comprised of cells. Why? It would seem inefficient to have so many individual nucleus, membranes, etc.? Specifically: Not all tissue is cellular. Much tissue is extracellular matrix. ...