The study of cells: their physiological properties, structure, environmental interaction, division, life cycle, and death, as well as the organelles they contain. Also known as cytology.

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Is collagen supplementation useless?

When collagen is digested is it broken up into usable components that the body can use to produce its own collagen? What evidence is there that supplementing with collagen type I & II etc.. can ...
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What were the first neural systems like?

I'm curious about the origin of the neural network. I'm thinking perhaps once life evolved beyond the single cell organism, it needed a simple neural network to coordinate those cells, and cell ...
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Why is heterochromatin localized next to nuclear lamina?

The heterochromatin is generally localized at the nuclear periphery (also near nuclear lamina), whereas active genes are preferentially found in the nuclear interior. Children with ...
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How many cells are there in the apical meristematic tissue?

How many cells are there in the apical meristematic tissue? Looking at this picture... , I would tend to think that there are few hundreds cells in the meristem tissue. But I guess this is a ...
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Can someone explain the color-changing unit (CCU) to me?

I've been physically carrying out serial tenfold dilutions on samples of Ureaplasma to work out the color-changing units (CCU). As a definition, the CCU is the highest dilution at which there is a ...
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A program for cell motility assessment with a batch process function?

Cell motility assessment is a branch of experimental biology or medical science. One example could be an assessment of treatment effects on sperm motility of an animal. The standard procedure involves ...
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Microscopy Book Suggestions

I've learned programming through great book recommendations, many from the Stack Exchange series of sites. I'm hoping to take this approach to gaining a fundamental understanding of how fluorescence ...
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64 views

What are senescent cells doing in our bodies? [closed]

I'm reading a paper that mentioned the elimination of senescent cells delays aging. I'd like to receive more information about it. The Baker study published in Nature demonstrates that targeted ...
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DNA is charged negative. Where is all the positive charge in my body?

DNA is charged negative because of its phosphate backbone. Since charges need to be balanced (so that there are no charges building up somewhere), what is the positive charge which neutralizes this ...
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67 views

peptide MHC microarray

"The recent technology is peptide–MHC microarray or artificial antigen-presenting chip. In this technique, recombinant peptide–MHC complexes and co-stimulatory molecules are immobilized on a ...
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120 views

Why doesn't the cytosol dissolve the polar structures?

we know that cytoplasm of cells are filled with water molecules and other hydrophilic molecules so my question is why the water of cytosol doesn't dissolve the ionic part of the lipid bilayer or why ...
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108 views

What do cells do when they aren't creating proteins?

I've always thought that the majority of the "work" in a cell is protein production, until I read the following. The Wikipedia article on the central dogma of molecular biology states this: 80% ...
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154 views

Can cell exist without Ribosomes? [on hold]

Last night I came across a question that goes as follows:- Cells cannot exist without a) cell wall b) cell membrane c) mitochondria d) ribosomes I am getting confused with option B and option D ...
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Regarding cancer cells and telomeres

If cancer cells have telomeres are they different than the telomeres in non-cancerous cells? Would cancer cell telomeres be somehow 'set-up' to function almost indefinitely; in other words are 'they' ...
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295 views

Why are red blood cells considered to be cells?

Wikipedia states that a cell is the basic structural, functional and biological unit of all known living organisms. Cells are the smallest unit of life that can replicate independently. It then ...
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380 views

How exactly does marijuana damage brain cells?

I've heard that THC can cause permanent damage to brain cells. I've also heard this reffered to anti drug propaganda. Another theory i've read is that temporary effects reduce intelligence but long ...
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125 views

Where does an organism store reserves of amino acids?

Where does an organism store reserves of the amino acids it needs to build various proteins it needs -- in the liver ? in the blood ? in every cell ? Thanks
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Localization of Protein Kinase-A

Is protein kinase-A located in the cytosol/cytoplasm of cells or in the plasma membrane? Also, is it considered a receptor molecule since it is dependent on cAMP? Any and all help is appreciated. ...
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Trimming of tRNA precursors

From Molecular Biology of the Cell (4th edition) by Bruce Alberts et al. (Chp 6, Pg 338) : Both bacterial and eucaryotic tRNAs are typically synthesized as larger precursor tRNAs, and these are ...
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338 views

How do nutrients get to the cells they need to get to?

I understand the basics of digestion. I know that nutrients get absorbed by the microvilli, enter the bloodstream and travel to the liver but after all that, what is the biological mechanism that ...
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Structure of biological membranes?

Integral membrane proteins have functional asymmetry i.e. they have two different domains of proteins performing different functions. these proteins have Tyr and Trp amino acid residues at the ...
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What will happen if we expose the brain to an intermittent light?

If a brain is exposed to an intermittent light are specific areas going to fire? If yes, which of them? Is there any experiment about this?
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Termination of translation

What dissociates first - the last tRNA, mRNA and release factors or the subunits of ribosomes? I tried searching this from Lehninger but couldn't get a clean answer.
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387 views

Beginning with centrifuge experiment

This is the first time I do a centrifuge experiment with my own centrifuge machine, it's just simple made by a rotor that can rotate the tube at high speed. As I know a centrifuge machine can be using ...
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154 views

Up to date B cell review

Where would I find an up to date (last 6-7 years max) review on B cells? I've tried searching through pubmed with filters, cochrane library, medline and various other resources including searching old ...
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56 views

Measuring the density of surface antigens

I'm trying to get a sense of the variety of methods used for determining the number of cell surface antigens and receptors. This is notably different from determining the affinity of these surface ...
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Are we more/less resistant to infectious diseases during an allergic reaction?

To my understanding, an allergic response is a non-adaptive response of the immune system to some molecule. The molecule in question is therefore "thought by the immune system" to be infectious ...
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How are lysosomes formed?

Lysosomes are irregularly shaped membrane bound organelles containing 50 different types of enzymes. But how are they formed? How are they produced??
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Does the cellular response to every receptor work the same way?

I heard somewhere that activating any receptor results in the same intracellular response (signaling) which involves NF-κB. If that is true, I hardly understand how the cells distinguish between ...
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epitope prediction/ mapping

B-CELL EPITOPE PREDICTION Regarding this article: "Such a molecule can be synthesized or, in case of a protein, its gene can be cloned into an expression vector."----- is a particular line in ...
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Mitochondria - are they really separate organisms that once merged into eukaryotic cells?

Theoretically, mitochondria are said to be a separate organism that is concerned with its own life and its own processes. In fact, it even duplicates individually. I know a similar question is here ...
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Can (any) human cells learn?

I'm not talking about single celled organisms, but actual cells in your body. Is there any evidence that they can learn to, say, navigate an environment or avoid an aversive stimulus like an animal ...
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64 views

How to study the effect on tau protein isoforms on microtubule based transport?

From what I read, A-beta plaques inhibit microtubule based transport of mitochondria when tau protein is present in the cell. How would I be able to do a test to see if one isoform of tau is more ...
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Explanation of the terms “downstream signaling” and “upstream signaling”

In molecular biology, what's the meaning of the terms "downstream signaling" and "upstream signaling"? What's the difference between them?
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Connection between genes and pathways

I am reading about a paper about inferencing pathway information in cancer cells. Authors refer to ERBB2 as a gene and a pathway. I don't have solid biology background. What exactly means when we ...
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Homework : Sodium Potassium pump

Why does sodium-potassium pump consume about 2/3 energy of a cell ? A.maintains appropriate membrane potential B.helps in co-transport I think it should be A.
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How did viruses learn to utilize the workings of a cell?

This is my first post here, so excuse me for its simplicity. Viruses can infiltrate a cell, overtake it and multiply. It has projecting fibers whose ends are shaped as kind of a "key" to a mobile ...
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Domains in cell membrane

How is movement of proteins and lipids between different domains of cell membrane prevented? Why is the noncytosolic layer not able to do lateral movements between domains but cytosolic layer is able ...
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Why did Fair Meiosis evolve?

How and why did Fair Meiosis evolve? I can hardly think that it provided a fitness advantage to the individual carrying the mutation. Why would it? Or did it evolve through lineage selection? Or was ...
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374 views

Will lipid molecules 'flip-flop' over a membrane without the use of an enzyme?

All of the references to this I can find refer to enzymes like Flippase making it 'easier' or 'more likely' that the translocation will occur, rather than actually make it possible. The following is ...
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Simulating Cell differentiation

I'm a computer programmer deeply interested in Biology. I wish to write a computer simulation for cell differentiation. I understand there will be seemingly impossible challenges in doing this. But ...
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Experiments in vitro vs those with dead organisms and fixated tissue

Does the term in vitro necessarily imply that the organism/organs/cells of study are dead? If not, is there an alternative latin term to refer to studies of dead biological matter ? (e.g. in ...
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319 views

How are different types of cells created from zygote?

In the process of mitosis that starts from zygote, how do different cells appear? What happens that some cells become one type and some another? For example, is there a cell that divides into a ...
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41 views

How are lesions in the RNA corrected?

I quite understand why thymine is present in DNA. So we can mark it out where cytosine undergoes a reaction and is converted to uracil. Then we can repair the DNA. But how can we make that out in RNA ...
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113 views

Difference between sequential and conformational epitope

Is the difference only in its structure? Like conformational epitope has 3D structure while sequential has a linear structure?(I have not studied biology since last 8 years and now I am going through ...
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What roles do cyclooxygenase, lipoxygenase, and epoxygenase have in signal transduction? [closed]

Besides oxidizing fatty acids to form prostglandins, leukotrienes, and epoxides, what other roles do cyclooxygenase, lipoxygenase, and epoxygenase have in signal transduction?
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75 views

Inductance in cell

In an animal cell, especially neuron and in particular its axon, while there is electrical resistance and capacitance mechanism in the cell, which play essential roles in the cable theory model of ...
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280 views

How do some plants grow in salt water, while others die?

My question is basically out of curiosity and comes from observing how certain plants (such as mangroves or salt cedar) can grow in seawater. If this gives the plant an advantage, why haven't all ...
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292 views

What kind of a microscope do I need to see cell organelles?

I would like to study cells and looking for a microscope that would allow me to see: groups of cells individual cell cells organelles I would like to target insects and mammal tissue. I would be ...
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Fusion of neuron with a S phase cell

There was some experiment in which a S phase cell was fused with other cell and the other cell also began to replicate DNA. Would the same happen if fused with nerve cell ? Why or why not?