The study of cells: their physiological properties, structure, environmental interaction, division, life cycle, and death, as well as the organelles they contain. Also known as cytology.

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Why it seems that principles of chemistry are not being applied in this biochemical process?

According to an answer in this question, my concept used below does not apply: In the non-cyclic photophosphorylation, consider splitting of two water molecules, then 4 e- (electrons) and 4 H+ ...
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41 views

Do chromosomes uncoil in interphase II

During interphase II, there is no S phase in which DNA replicates. However, in this stage, do the chromosomes remain wound? Or have they unwound into chromatin form, and recondense during prophase II? ...
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7 views

Function of NEZHA gene

What is the function of NEZHA? What effect does it have on microtubules and PLEKHA7? What happens after it has been knocked down?
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23 views

What’s wrong with a shriveled cell?

When you place a cell into a hypotonic solution, water rushes into it and it bursts/lyses. Thus, the cell dies. However, when you place a cell into a hypertonic solution, water rushes out of it and ...
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39 views

How is CO2 related to acidity?

In a plant cell why does increase in concentration of CO2 increase the acidity of the cell sap. Thank you
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25 views

Types of fermentation? [on hold]

I read about several rarer forms of fermentation such as ABE, and heterolactic. What is the full list of all known types of fermentation, and what are the differences between them? Edit: I only want a ...
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20 views

Converting miRNA names

I need to convert all of my microRNA names e.g. hsa-miR-30e-5p to e.g. entrez gene IDs, ensemble IDs or another ID. Does anyone know a good ID conversion tool for microRNAs? (I managed to convert it ...
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17 views
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44 views

Structure of Cell

Are cells spheres or ovals/circles bound by phospholipidbilayer? If they are spherical how are we able to see the nucleus through the phospholipid bilayer under a microscope?
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18 views

mRNA extraction from mice ears.

I am trying to extract RNA from mice ears and for some reason I don't have RNA when I perform the electrophoresis. I directly cut the ears and I put it in a tube with a bead and trizol. then I place ...
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1k views

What is our skin made up of?

Again, it is a basic question. What is our skin made up of? is it made up of many cells arranged in a systematic way or is it just like any layer say of a book?? what is the difference? where is the ...
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31 views

Can the activity of bacteria be influenced by magnetism? [on hold]

Some organisms are tuning their direction on a magnetic field. But are bacteria also reacting on magnetic fields and can it be used in health therapie as a kind of 'antibiotic'?
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1answer
51 views

What causes swelling after impact?

Why does the head swell after getting hit by something hard? What is the liquid that forms after impact?
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109 views

Why did multicellular organisms evolve when a single cell can survive on its own? [duplicate]

Since unicellular organisms can survive, why would there be evolution of multicellular organisms?
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48 views

What do proton pump inhibitors do?

I know that sodium azide and 2,4-DNPH inhibit proton pumps. The azide is called an inhibitor and 2,4-DNP is called uncoupler. I want to know what's the difference between the mechanisms of action of ...
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1answer
84 views

In the video, “Inner Life of a Cell”, what's the empty space between the molecules?

In the video, ["Inner Life of a Cell"][1,] there's a lot of empty space between the proteins. Is it just a simplification (i.e. they omit smaller molecules)? If so, what are the smaller molecules ...
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1answer
30 views

Normal cell diffusion in normal organism?

We know, that cancer cell can travel across an organism. Is this ABSOLUTELY impossible for NORMAL cells? For example, is it EXACTLY ZERO probability to find some bone cells inside liver or some skin ...
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2answers
107 views

Blebbistatin effect on vesicles

Blebbistatin is a drug that specifically inhibits the assembly of myosin in the cytoskeleton. What effect would you expect blebbistatin to have on intracellular vesicles? ...
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1answer
40 views

Why did eukaryotic cells develop? [closed]

If eukaryotic cells can survive in extreme conditions, then why are their still prokaryotic organisms?
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57 views

Could a single cell be brought to life?

If a scientist is observing a single cell under a microscope, and then realizes that the cell has died, is it possible to bring that dead cell back to life? For my inquiry, let's assume that the ...
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0answers
45 views

Is it true that human cells grow in levorotation? [closed]

I remember reading this in a popular science magazine, some 20 years ago: that in most of the living organisms, cells grow in levorotation and very few grow in dextrorotation. That means, the ...
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25 views

Is it possible to make the human cells totipotent? [closed]

we all know humans are not capable of regenerating from a single cell. Is there any possibility that we can make cells totipotent?
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1answer
27 views

ADCs: by what mechanism are antibodies internalised [closed]

I read that ADCs (Antibody-Drug Conjugates) act by a -mab for a particular target being bonded to a cytotoxic compound. From my high-school-with-crayons knowledge of antibodies, however, one part of ...
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0answers
28 views

Bacteria surviving a β-lactam antibiotic

What changes can occur in the cell wall of a bacteria for it to survive a β-lactam antibiotic? I think that because a bacteria possesses peptidoglycan in its cell wall, they are β-lactam sensitive, ...
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21 views

What percent of cells are lysed when I make my smoothie?

This is an entirely irreverent question, but it does concern biology. I'm a physicist by training so I like to be able to estimate order of magnitude. I made a smoothie the other day with milk, ...
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1answer
29 views

How does symbiogenesis explain reproduction of organelles along with the cell?

Symbiogenesis is an evolutionary theory that says that prokaryotes eventually evolved into eukaryotes (having multiple organelles and better structure) by forming symbiotic relationships with other ...
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1answer
19 views

Advantage of GCPRs over RTKs or other receptor protein kinases

My book lists two important differences between GCPRs and receptor protein kinases: GCPRs do not directly activate a signal transduction pathway. It only does so indirectly, via a G protein. On the ...
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2answers
34 views

Growth factors vs. mitogens

According to Campbell Biology, A growth factor is a protein released by certain cells that stimulates other cells to divide. and according to Wikipedia, A mitogen is a chemical substance ...
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58 views

Density of cells in human tissues?

Where can I find values, or estimates, of the density of cells in human tissues? Maybe an overall estimate, or distinct values for distinct tissues? Or maybe not human, but mammal tissues (which ...
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1answer
140 views

Difference between protein channels, protein carriers and protein pumps?

I'm revising for my biology exam and I don't fully comprehend the difference between protein channels, carriers and pumps. I know that: Protein channels do not require ATP (passive transport) The ...
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21 views

Vitamin E Production and Sun Light [closed]

Do animals with fur need sunlight to produce vitamin E? It it necessary to have sunlight in humans to make it?
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2answers
243 views

How many centrioles/basal bodies are there in multi-ciliated cells throughout the cell cycle?

I thought there were only two centrioles per cell, that convert to the basal body at some point during the cell cycle. I also thought there's one basal body per cilium, so I'm not clear on where the ...
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1answer
54 views

HOw are AMP's “recharged” to become ATP's in a cell?

I understand that after the translation stage of ribosomal protein synthesis, tRNA molecules are floating in the cytoplasm without attached amino acids until they find the correct aminoacyl tRNA ...
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1answer
63 views

Which step in endocytosis requires ATP?

Everybody seems to agree that endocytosis is an energy-using process, and as such requires ATP hydrolysis. However, which particular step requires it? More precisely, which 'molecular machine' ...
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1answer
161 views

Is there a karyotype database for human cell lines?

I'm looking for the karyotype of a specific cell line. Some karyotype are well known, such as HeLa or some carcinomas, but some are very hard to find, such as LG2 (B cells). Is there a database ...
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1answer
25 views

How does the drug MBC effect the depolymerization of microtubules in eukaryotic cells?

I have tried to look for the mechanism of how methyl benzimidazol-2-yl-carbamate affects microtubules in eukaryotes, but what I found wasn't very useful: Quilan et al 1980 assert that it acts by ...
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1answer
54 views

How difficult is it to make a shRNA/miRNA/siRNA to silence/knockdown NaV1.7 voltage gated sodium channels in humans?

There have been various research projects that experimented with shRNA/miRNA/siRNA to specifically silence/knockdown NaV1.7 voltage gated sodium channels in small animals like rats & guinea pigs. ...
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11 views

Do you know of any scratch assay video databases?

It would be of great help for a statistical work we have been asked to carry out at our University. Thank you very much in advance.
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1answer
48 views

Do snRNAs exit the nucleus or not?

In Molecular Biology of The Cell (Alberts, et al., 2015), it lists the various RNAs that are trafficked through the Nuclear Pore Complex (NPC) into the cytoplasm. The list includes snRNAs, but I ...
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2answers
81 views

At any given moment, how much energy is stored in the human body as ATP?

At any given moment, approximately how much energy is stored in the human body as ATP in the ADP-P-bond? This of course depends on what type of cell it is and the activity of the individual in ...
3
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1answer
40 views

Can a cell start a mitosis if it lacks energy or molecules to complete it?

I'm wondering whether a cell can start a mitosis if it lack molecules or energy to fully complete it. From what I'm reading on wikipedia the cell passes most of its time in the interphase in which the ...
3
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1answer
31 views

What is the purpose of requiring two separate binding systems for the antibody response?

I've read that in most cases, B-cell activation requires helper T-cells. This requires antigen binding by both antibodies and T-cell receptors, using two different antigen-binding proteins, ...
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2answers
30 views

At which end does polymerization of microtubules occur?

My book says that polymerization and depolumerization of microtubules occurs on the + end however, I've found a note that says that depolymerization occurs on the - end. I need help please :) thank ...
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48 views

Is HSV-vector-mediated miRNA expression in dorsal root ganglia stable?

My question is on the following article: "Reduction of voltage gated sodium channel protein in DRG by vector mediated miRNA reduces pain in rats with painful diabetic neuropathy" My question is, do ...
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0answers
21 views

Effects of pH vs membrane potential within a cell? [closed]

How are these two concepts related? Does changing each result in the same effects? As in: what kind of reactions/processes would be affected if we changed the pH within a cell? Would the results ...
3
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0answers
31 views

How was gene therapy able to CURE some diseases (I guess on cells that do NOT regenerate)?

Here's where I'm getting confused... I thought that gene therapy, when done on target cells that regenerate themselves constantly, can be effective for a limited time only (aka. The achieved effect ...
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2answers
41 views

In cell division, are daughter cells identical?

I understand that after a cell replicates, there will be two daughter cells instead of one. But wouldn't one of them be the old cell that created the second one? The old cell having gone through G0, ...
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1answer
21 views

Constant or variable number of chiasmata during recombination?

During recombination, is the number of chiasmata consistent for each gamete and are the chiasmata regions consistent within a single organism?