Tag for questions related to the process of cells receiving a stimulus from its environment, or from itself (autocrine signaling), and responding as a result of the stimulus.

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Cell biology books

I'd like to know, what is the best list of books for non-biologist to understand, how signalling between organels is organized inside of eukaryotic cells. I really want to get how cell as separate ...
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Why RTK Truncations So Common in Transformations

So if we can understand that RTKs are 'floating' around the surface of a cell as monomers until ligand binds one of the monomers and thereby acts as a bridge to facilitate binding to a corresponding ...
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What is the essence of difference of how different chemicals affect the same receptor?

It is known that various chemicals can bind to the same receptor type, producing different effects. Be these chemicals agonists or antagonists, there are more variations in how they influence the ...
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When and How do pacemaker cells develop during the cell aggregation process of Dictyostelium discoideum?

I was reading a paper by Tang & Othmer about oscillations and waves in Dictyostelium discoideum. Under certain condition like starvation period in the life cycle of a Dictyostelium discoideum ...
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What's the purpose of Cdk activity having more than one method of becoming inactive?

Cdk becomes partially active once its bound to cyclin and then gets phosphorylated and fully active once a Cdk-activating kinase (CAK) phosphorylates the partially active Cdk. This fully activated Cdk ...
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Is EGF-mediated proliferation symmetric?

It's known that the MAPK signaling cascade (say, ERK) is downstream of EGFR in epithelial cells, and that EGFR activation can cause proliferation in some cell types in some situations. My question is ...
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What is the lifetime of the vasopressin receptor V2?

I was looking at the production of vasopressin receptor 2, also known as V2R or ADH-R. What I found is that it is coded by the AVPR2 gene and degraded by the Alix protein (source). But I did not get ...
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histamine inter-cellular and cytoplasmic binding site

I noticed that HRH (histamine receptor) has an inter-cellular and cytoplasmic binding site of anti-histamines which are equal in binding energy. Does anyone know what is the function of the well ...
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What information do bipolar cells encode?

Short version: I don't see what information on-centre bipolar cells are actually capturing. Longer: Actually, the question could be extended to on-centre retinal cells as well, but I'll focus on ...
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Arginine finger for regulating GTPase activity of heterotrimeric G-proteins as well?

I've seen video on iBiology discussing mechanism of Ras-Gap protein regulation of Ras protein (monomeric G-protein) involving an "arginine finger' from Ras-Gap for stabilization of intermediate in ...