Questions pertaining to variation in the number of copies of a chromosomal region.
3
votes
1answer
49 views
Is copy number variation dynamic?
Is there any evidence showing that copy number variation changes over time? I'm wanting to model interactions in expression level as a dynamic bayesian network, but an assumption my approach will need ...
4
votes
1answer
274 views
What is a focal copy number variation?
Often, genetics studies, especially genome wide ones, talk about "focal copy number variations" in genes or regions of the chromosome. I know what a copy number variation is. What does "focal" mean, ...
7
votes
1answer
133 views
What is the difference between copy number changes with and without allelic imbalance?
I require some clarification on copy number aberrations (structural gain and loss in chromosomes). From what I understand, gain/loss per se can be divided into two types.
Consider two alleles, A and ...
11
votes
2answers
231 views
What is the tRNA gene copy variation between different yeast strains?
I just started working on predicting steady-state protein levels from different codon usage bias measures. I have whole-genome sequences (it's NGS data) from different strains of S. cerevisiae and S. ...
