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Why can't intermediate filaments be used as tracks by motor proteins?

A motor protein like kinesin-1 cannot use an IF as a track because it lacks polarity. Can someone elaborate on this answer?
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What are the effect of microtubule or microfilament inhibition on yeast expression profile?

I was wondering whether anyone has looked at what are the expression changes in yeast when the microtubule or the microfilament polymerization is inhibited? Have there been whole-genome studies?