2
votes
1answer
53 views

How do cells figure out the big-picture shape?

I'm wondering what makes cells to divide (and stop) in such a way that they make our hands the shape that our hands are...
2
votes
1answer
364 views

Manipulation of gene expression using VP16 fusion and engrailed fusion to a transcription factor?

Today, a presenter briefly mentioned that gene expression in sea urchins during development might be manipulated using VP16 and engrailed fusions. On a slide, it said that expression might be ...
6
votes
1answer
102 views

Bicoid regulation of hunchback

I'm learning about development via the example of Drosophila embryogenesis. I understand that bicoid regulates hunchback, among other genes. My question whether the regulation is direct or indirect? ...