Differentiation describes the process in the development from more general cell types into higher specialized cell types.

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How do expression levels change along lineages?

Is there any general trend between gene expression levels (or transcription levels) and cell lineages? For example, I would naively expect that stem cells express less genes as they have the ability ...
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mutant and variant differentiation

Can anyone clearly differentiate between a variant and a mutant in genetics. I am confusing these terms a bit, as the evolutionary aspect also comes to my mind.
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differentially expressed genes of the treated with estradiol samples

I did differential analysis on samples treated (G1E-ER4) with estradiol (differentiation induced by estradiol) and control (G1E). The genes that I gor as differentially expressed in G1E-ER4 showed ...
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cell specialisation and their location

When we create new cells, how come they are of the 'right' type at the 'right' place? For example, when I make a new cell on my lips, it's obviously not the same as a new one in my kidneys. Is the ...
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Cell-type specific methylation profiles: original reference finding?

This is a general question, and a specific question. I'm looking for the original reference that first talked about how DNA methylation profiles are cell-type specific. This is specific, because I ...
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Bacterial Cell Problem

A microbiologist has discovered what she thinks are two new types of algae. The first cell (Organism 1) appears cubic and is approximately 1.5 μm long, 1.5 μm wide and 1.5 μm deep. The second (...
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DIfference between diversification and differentiation

In Adaptive dynamic : what is the difference between Ecological Differentiation and Ecological Divergence ?
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Where can I find a full genealogy of human cell types?

It is said on Wikipedia, that the precursor of blastocyst is a morula, and that the precursor of morula is a zygote. This gives us the part of genealogy tree of cell types. Unfortunately, no full ...