Tagged Questions
4
votes
1answer
75 views
How does “inheritance of methylation” of DNA and/or histones work?
What are the current models/ideas describing the mechanisms explaining inheritance of methylation on DNA resp. histone level?
Is there evidance of this "setup" information being really ...
10
votes
1answer
298 views
Why is the 3'UTR region highly methylated in most of the human genes?
Most of the human genes are found to be highly methylated in their 3'UTR region (0.8-0.9%). I was wondering if there is any specific reason for this?
14
votes
2answers
177 views
Can methylation from DNA get copied to RNA during transcription?
Methylation on gene-body and 3'UTRs if copied to mRNA can potentially regulate post-transcription modifications or expression regulation. But I'm not sure if they are maintained after transcription or ...
10
votes
1answer
182 views
How do CpG islands remain unmethylated?
In most of the genome CpG sites are pretty much always methylated, but CpG islands are instead often unmethylated. This has been linked to the fact that they often are associated to transcripted ...
