A structural aberrancy in DNA, as opposed to a sequence change (mutation). Often caused by reactive species.

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Aging in yeast (and other eukaryotic) and DNA damage

Yeast aging - there is daughter cell and mother cell. Daughter cell is fresh and mother cell dying after some count of births. What with accumulated DNA damage? One of theory of human aging is ...
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G>T transversion VS. T>G transversion?

So I'm reading about how mutations in DNA can be caused by oxidative damage. An example of a product of oxidative damage is given: 8-oxo-7-hydrodeoxyguanosine My textbook says that this product ...
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Which is the best way to fix and preserve comet assay slides before staining with Ethidium Bromide?

I want to use the method of Single Cell Gel Electrophoresis (comet assay). I have many samples, but I don't have the appropriate microscope. So I have to preserve my slides until the time comes for ...