Tagged Questions
0
votes
1answer
58 views
Lineage selection in plasmid evolution
I've been reading through Paulsson (2002) and I am not sure what he means by "lineage selection" in the second to last section. The paper deals with plasmid replication, and mostly concentrates on the ...
3
votes
0answers
39 views
Structure of fitness landscapes in the NK model
The NK model of rugged fitness landscapes consists of $N$ sites where fitness contribution of each site depends on its state $\{0,1\}$ and is epistatically affected by $K$ other sites. When defining ...
3
votes
1answer
63 views
Are there natural selection experiments that quantitatively agree with theoretical modeling?
Has anyone ever conducted an evolution experiment and quantitatively compared it to theory? For example, has anyone ever put bacteria in a million petri dishes filled with antibiotics and calculated ...
4
votes
1answer
106 views
Is local equilibrium a reasonable assumption for evolutionary processes?
Whenever I look at discussions of fitness landscapes (in particular, Kauffman's NK model) the questions tend to resemble:
The population is at a local equilibrium, but another equilibrium of ...
3
votes
1answer
56 views
When does weak selection produce qualitatively different results from strong selection?
In evolutionary game theory, it is typical to model organisms as having a base fitness that is modified slightly by the game interaction. The ratio of the game effect versus the base fitness ...
5
votes
3answers
369 views
How exactly are game theoretical evolutionary models described during implementation for computer simulations?
When a biologist or a layman tries to reason the evolutionary explanation for something, they would simply use English with some math thrown in (for a random example, pick any explanation out of "The ...
5
votes
1answer
147 views
Computational/mathematical models for predicting phenotype from genotype
Karr, Sanghvi, et al. (2012) propose a whole-cell computational model for predicting phenotype from genotype in Mycoplasma genitalium. Their model simulates myriad cell processes such as DNA ...
3
votes
2answers
163 views
Short-term Lamarckism in asexual single cell organisms
I was reading through the Karr et al. (2012) whole-cell computational model. One of the things they did was to induce single-gene disruptions in their model. They observed several to be fatal, but:
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5
votes
1answer
89 views
Alternatives to fittest-win and Moran processes as simple mathematical models of selection
When modeling selective sweeps as a micro-building block in models of macroevolution (not to be confused with misuses of this in creationist arguments), I use the fittest-win model of selection as a ...
13
votes
2answers
444 views
Why is 'Grudger' an evolutionary stable strategy?
I am currently reading 'The Selfish Gene' by Richard Dawkins, which I am sure many here have read. The topic are evolutionary stable strategies (ESS) regarding cooperation.
I apologise for the long ...
