Changes in the heritable attributes of populations of organisms over time. Major mechanisms include drift, natural selection, mutation, and gene flow (migration).

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Why do genetic drift generates negative linkage disequilibrium?

The very first sentence of the abstract of this article are: "In finite populations subject to selection, genetic drift generates negative linkage disequilibrium, on average, even if selection ...
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125 views

Heterozygosity and overdominance

Consider $m$ loci with heterozygote advantage (overdominance) such that the fitness of the two homozygotes is $1-\frac{s}{2}$ and the fitness of the heterozygotes is $1+\frac{s}{2}$, where $s>0$. ...
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89 views

Are people genetically predisposed to being interested in specific fields/ideas? How does specialization occur?

I'm not sure if I formulated my question well, but I'm curious about a couple statements made by Steven Pinker and and James Heckman. In this interview: ...
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40 views

definition of tempo and mode in evolution

I am reading Punctuated Equilibria: The Tempo and Mode of Evolution Reconsidered, which mentions the "tempo" and "mode" of evolution. I'm not familiar with the related literature and when I google the ...
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25 views

Definition of Linkage Desiquilibrium (LD)

According to [wiki][2], linkage disequilibrium $D$ equals $$D = x_{11} - p_1\cdot q_1$$ where: $$ \begin{matrix} \text{Haplotype} & \text{Frequency}\\ A_1B_1 & ...
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19 views

Source of information on the evolution of aging/senescence

Do you know a good review (published peer-reviewed or an online course or whatever) that offers a good overview of all hypothesis explaining the various patterns linked with aging? I'd like this ...
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350 views

Advantage of being deuterostome

We know that most of the so called "Advanced" organisms are deuterostomes (i.e., development of gut starts from anus). Is there any evolutionary advantage of that? If not, why and how did it evolve?
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74 views

Model for fluctuating selection

Is there any mathematical model to predict the behaviour and long-term consequence of counter-acting selection at different time scale? For example, let's consider the bi-allelic gene $A$, with ...
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49 views

Effective population size and overlapping generations

From this book; If generations overlap, then the effective population size $N_e$ does not equal the population size $N$. I know mathematical formulations in order to find the effective population ...
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49 views

Effect of natural selection on phenotypic variance

Short background Theoretically speaking, natural selection causes a decrease in genetic variance and because the environmental variance should remain unchanged, natural selection causes a decrease of ...
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81 views

What are the costs associated with carrying lots of genetic material

What are the costs (if any) associated with carrying lots of genetic material? energy for copying? raw material for copying? space in the cell? Maintenance cost (matter and energy)? time to copy is ...
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104 views

Population genetics and the fitness probability distribution. Why is the arithmetic mean all we need?

When recording change in allele frequency in diploid, bi-allelic, infinite and panmixic population we usually use this kind of equation: $\delta_p = \frac{p * q *( p (w11 - w12) + q * (w12 - ...
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54 views

Book recommendations for evolutionary models

I was recently working on getting a statistical model of a DNA sequence. To do this I found that understanding evolution quantitatively seems to be quite important. I would really appreciate any book ...
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93 views

Why haven't land animals evolved beyond urination?

It occurred to me (while urinating) that this would seem to be selected against because water is a scarce resource. Why are we constantly losing water we don't need to through urination? What is ...
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42 views

List of heritability estimates in humans?

Many people on this site ask questions that directly or indirectly have to do with heritability in human. Do you know a list of estimates of heritability of various traits in humans? Or could you try ...
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40 views

How are new chromosomes replicated into the next generation via sexual reproduction?

If an individual has a new chromosome, which is very unlikely to happen, he will not have any luck in finding a sexual partner with this same trait. How will the offspring inherit this trait. And ...
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129 views

Opposite results between Blomberg's K and phylogenetic signal in Phylocom (AOT)

I've been trying to test for significant phylogenetic conservatism in some plant traits. So far I used R-package picante (Blomberg's K) and AOT in Phylocom. So far these two methods yield completely ...
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68 views

Can I force evolution in a group of cells by removing all the smaller cells?

I actually have algae growing in water in a container. I was thinking if it was possible to filter the water so that all the small cells will be filtered out and only the bigger ones will remain to ...
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24 views
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Coalescent Theory - Probability for $k$ alleles that of one coalescence event occured $t+1$ generations ago

From this textbook Under the wright-Fisher model of genetic drift and under the assumption that all alleles are neutral, the probability that $k$ alleles had $k$ distinct parent alleles the previous ...
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57 views

Does recombination increase the additive genetic variance for fitness?

On this article, first column, eighth line of the introduction: By bringing together favourable alleles from different chromosomes, sex and recombination increase the additive genetic variance for ...
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68 views

How does GC-content evolve?

Background GC-content refers to the frequency of base pairs that are either C or G in the genome, or in other words the number of GC base pairs divided by the addition of the number of GC base pairs ...
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418 views

Evolution: How could all useful traits evolve simultaneously?

I have a basic question about evolution, for which I never found an answer. I understand how evolution works if we focus on one specific organ or trait. With each generation, some organism is more ...
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2answers
86 views

Heterozygosity under genetic drift

The wright-Fisher model of genetic drift is: $$p_{ij} = \binom{2N}{j}\left(\frac{i}{2N}\right)^j \left(1- \frac{i}{2N}\right)^{2N-j} $$ ,where $\binom{2N}{j}$ is a binomial coefficient. From this ...
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151 views

What is the beneficial function of IgE antibody?

Dont tell me the "function" of IgE is to cause allergy ! In whatever texts I have seen it is written that IgE is important to cause allergies but what is the beneficial function of IgE ? Why was it ...
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294 views

How does the genetic code evolve?

After looking at this question, some other questions poped in my mind. The DNA code is redundant, there are 20 amino acids for 64 possible nucleotide combinations. Therefore some amino acid are coded ...
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223 views

How do we know that dinosaurs were related to lizards and/or birds?

Do we clearly know what the living closest relative of the dinosaurs are? And connected to the first question, in scientific manner how do we know these relationship between extinct species and living ...
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49 views

Additive genetic variance with $n$ loci

The genetic variance of a quantitative trait (the quantitative trait in question is fitness) can be express as the sum of two components, the dominance and additive variance: $$\sigma_D^2 + ...
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88 views

Earliest ancestor of humans who could integrate into modern society

Assuming the current model of human evolution to be correct, approximately when did the earliest ancestor of humans live, who was intelligent enough, that if raised from a young enough age, could ...
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48 views

Evolution from Mating types to different sexes

Imagine a lineage of multicellular organisms that had mating types and evolved their mating types into sexes. What are the possible mechanisms that might have brought this lineage to evolve sexes from ...
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2k views

Why are there no wheeled animals?

In physics, "almost everything is already discovered, and all that remains is to fill a few unimportant holes." (See Jolly.) Therefore, on Physics SE, people are veering off into different directions: ...
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131 views

Why do different humans look different?

Although farmers appear to be able to tell their cows apart, cows look very much alike to me. And this similarity in appearance seems to be a general trail across the animal kingdom: one individual of ...
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Propagation of tool use in primates?

There are several famous cases of great apes demonstrating a surprising degree of wherewithal in communication and tool use - even monkeys can learn some tool use from each other observationally, even ...
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42 views

Book recommendation on selective breeding?

I am looking for a good book that gives a nice overview of the science and technics of selective breeding. I am particularly interested in the use of population genetics to support decision in this ...
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1answer
41 views

Why do the neuron pathways decussate?

I learn about the brain right now, and there are crossing of neuron pathways everywhere; in the thalamus, the medulla oblongata, the pyramidal tract... And I don't understand why? What is the reason ...
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34 views

List of the biggest companies that work in selective breeding

Looking at this question, I've been wondering, What are the biggest private companies which work in both animal and non-animal selective breeding? Let me know if Biology.SE is not appropriate for ...
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22 views

Triune brain model

I have heard about the triune brain model in biology class, but my teacher does not know much about it. What I'm curious about, is this model accepted by most of the neuroscientists, or is it just a ...
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1answer
81 views

Additive genetic variance with $n$ alleles

The genetic variance of a quantitative trait (the quantitative trait in question is fitness) can be express as the sum of two components, the dominance and additive variance: $$\sigma_D^2 + ...
5
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1answer
78 views

Hill-Roberston effects and effective population size

From this article, first page, middle of the second column: Even if harmful alleles do not become fixed, they can still reduce the efficacy of selection on neighbouring loci through a process ...
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Why does the slope of parent-offspring regression equals the heritability in the narrow sense?

Background ---- Notations and assumptions ---- let $W_{ij}$ be the fitness associated to the genotype $AiAj$. $x$ is the frequency of the allele $A1$ in the population. The frequency of the allele ...
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Fisher's Fundamental Theorem of Natural Selection

Ronald Fisher discovered what he, with humility, called the Fundamental Theorem of Natural Selection. This theorem says (in its modern terminology): The rate of increase in the mean fitness of any ...
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63 views

Life on other planets [duplicate]

first of all I'm not sure if I should post this here or in the astronomy stack. I think biologist are more likely to answer my question. To make it short: Why when looking for any sort of life on ...
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83 views

Effect on fitness of mutations

What is the distribution/probability density function (PDF) of impacts on fitness of new mutations? I very welcome any partial answer that does not give the whole PDF but just some information ...
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How did the first self replicating organism come into existence?

When people try to explain evolution, they tell me that evolution is a cumulative result of mutations & natural section of the more superior individuals of a particular species. I think I'm fairly ...
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115 views

Cyanobacterial photosynthetic oxygen yield

I am somehow not convinced that biotic factors are solely responsible for creating 21% of atmosphere (around 40 million moles of oxygen). There may be additional issues here. Since cyanobacteria ...
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1answer
35 views

Dominance/recessivity of new mutations

What is the distribution/probability density function (PDF) of recessivity/dominance of new mutations? I very welcome any partial answer that does not give the whole PDF but just some information ...
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46 views

How can a recessive allele propagate until they manifest?

Suppose a specific gene has two possible alleles. In a given population all members have only the dominant one. By a mutation on member receives the first recessive allele of that population. Is it ...
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87 views

building intelligent structure with random evolution requires series of non useful steps

In order to build an intelligent design such as a bridge or a mechanical watch, you need a series of non useful steps. As far as I understand, in random evolution theory, the "intelligence" involved ...
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335 views

What is the viability of Intelligent Design as a supplement to chemical abiogenesis and Darwinian Evolution?

First of all I am not endorsing Intelligent Design (Wikipedia link); I'm asking this because I (someone who does not have a background in biology, organic chemistry, or philosophy) got into a ...
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8answers
537 views

How does the creative process of Biological Evolution work?

In order for nature to go from microbes to man, there needs to be new information. Where does this new information come from? It is understood that Evolution basically involves three elements. ...