RNA Sequences corresponding to genomic regions which are retained in processed RNA (i.e., not spliced out).

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Can intron become exon in alternative splicing?

From this image We can saw several exon that is actually intron in other gene. It's not a really different gene, it's an alternative splicing of a gene. My background is not biology so is it ...
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Is intron removal coordinated?

Are the introns present in a nascent rna molecule removed simultaneously or are they removed in some sort of sequential fashion or is removal completely random?
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Why low variant frequency in exomeseq data (ANNOVAR)?

I've got an annotated ANNOVAR file with 300.000 nucleotide variants of 4 genomes. There's one thing I don't understand when looking at the data: Why are the variant frequencies so low in comparison to ...