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0answers
23 views

Is targeted fat loss really impossible? [closed]

Spot reduction is impossible, because muscles can't directly burn the nearby fats. What is interesting, when i look around, i see that almost everybody older than 30+ has belly fat, even though they ...
2
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1answer
30 views

Can lactate be created in ketosis?

After looking at Cori Cycle (from wikipedia) I have a question about how the lactate can be produced in ketosis. According to this article: in a low-glucose state, where the body senses that ...
2
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1answer
39 views

Does the body prioritise the use of available sugar before fat?

Let's say you eat a very unhealthy snack that contains 90% sugar and 10% fat. Would somatic cells not start using the fat for energy until all the sugar is used up? Does the body not use fat at all ...
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0answers
22 views

If chylomicrons can not get into the capillaries, how do they supply to tissues?

The transport of chylomicrons is into the lacteals mainly because they are too big to get into the capillaries and yet they later supply triglycerides in the extra hepatic tissue by traversing in the ...
3
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2answers
65 views

Can bacteria metabolize fatty acids for fuel?

I'm not a microbiologist, but rather a physiologist curious about microbial metabolism. Much like humans bacteria can utilize glucose, but when it comes to long chain, medium chain, or short chain ...
2
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0answers
21 views

What is the function of CETP?

I read up that CETP transfers cholesterol from HDL, which collected it from tissues, to VLDL. This VLDL is then sent back to the tissues, ultimately forming LDL internalised by cells. What is the ...
2
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0answers
28 views

What is the rationale behind reverse cholesterol transport?

Reverse cholesterol transport is transport of cholesterol from the tissues back to liver/VLDL. My question is why do the tissues have this extra cholesterol in the first place? Why would you ...
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0answers
15 views

Energy efficiency of carbohydrate > fat conversion

How efficient is the human body in converting surplus carbohydrate into fat? E.g., if you have 100 calories' worth of carbohydrates at the start of the process, how many calories' worth of fat will ...
0
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1answer
56 views

How body loses more fat in CO2 form than in sweating form? [closed]

Yesterday, I saw TV Game Show. There is question like this: Body loses more fat in which form? It gave 4 options: 1) CO2 2) sweating 3) xxx 4) xyz sorry i didn't remember 3 & 4 options. ...
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0answers
37 views

What is the actual function of HDLs and CETP?

I know that HDLs collect cholesterol from peripheral tissues and transport it back to the liver using SRB1 - Reverse cholesterol transport and dumping it in bile. So the tissue is producing some extra ...
3
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2answers
121 views

Bodyweight loss vs calorie shortfall

I have read that 1g of pure fat has 9 Calories. If I dieted successfully in a way that did not cause me to loose muscle, and I had a cumulative calorie shortfall of 90,000 calories. Would that ...
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0answers
52 views

How much energy would it cost to synthesize all cholesterol requirements de novo?

Imagine a scenario in which some person is unable to absorb any dietary cholesterol because of some intestinal mutation (for example). Thus, they have no cholesterol available from their diet for ...
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1answer
95 views

Is there an evolutionary advantage for coconut oils to be rich in saturated fats?

I know that coconut oil is composed of multiple saturated fatty acids, but is there a reason why this would have increased the fitness of the coconut plant?
2
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1answer
61 views

Metabolic efficiency for fats and sugars

I am making an exercise for physics students about the first law of thermodynamics, burning heat and evaporation heat. So my idea is to use cycler which runs on fats and sugars where proportion ...
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2answers
66 views

What are the differences between carnitine forms?

I've heard of L-carnitine, acetyl L-carnitine and L-carnitine L-tartrate. What form(s) occur in meat? What form does the human body manufacture? Is L-carnitine just a shortened name for L-carnitine ...
0
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0answers
30 views

Consumption of different type of energy when one is inactive

I'm wonder if there is any study done on this and what are the results? how much of each type of energy one's body(healthy normal person) uses when inactive(seating down) I know there are alot of ...
0
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1answer
50 views

What would happen if most the fat in your body was rapidly converted into energy in 2 minutes? [closed]

It all started out as an argument I had with my friend.He said that "it would be the equivalent of catching a fire and burning" But all I thought would happen is that you would now be very hyper ...
2
votes
1answer
90 views

What happens when we eat excess fat?

The fats in our body are stored in fat cells. When we over eat fats does the size of our fat cells increase, are more fat cells generated, or do we "throw out" excess fat?
7
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1answer
176 views

If eating 100% fat 2 times more worth the energy I spend during the day, will I store body fat?

So in theory, insulin hormone is the one that tells the body "eat more. don't burn body fat". Alongside with glucose blood level regulation and turning excessive glucose into liver (which later goes ...
0
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0answers
53 views

Why doesn't the body optimize how many fatty acids it burns?

Ketone bodies are produced due to an excess of fatty acids being burned (accumulation of acetyl-CoA) so my question is: Why doesn't the body simply regulate how many fats it burns so it doesn't have ...
4
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0answers
42 views

Cholesterol's role in lipid uptake [closed]

I'm studying the digestion of fats and I understand that our dietary fats mostly consist of triglycerides. We absorb the fats and eventually they end up in a muscle/adipose cell for storage (as ...
2
votes
1answer
137 views

Is there any disadvantage to having a really low adipocyte count in our times?

The key feature of adipocytes seems to be energy storage. Today humans in Western countries don't have to hunger and have therefore less need to store energy in fat cells. Do adipocytes have ...
0
votes
1answer
51 views

Can Omega 3 Fatty Acids prevent chest pain in periodic Atrial Fibrillation?

It is debated if omega-3 polyunsaturated fatty acids (N3PUFa) may be effective in preventing AF (atrial fibrillation), meta-analysis here. However, much less has been considered this: Do N3-PUFAs ...
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2answers
150 views

Burning fat transferred from one part of the body to another

While doing some research on cosmetic surgery, I discovered that there are several ways of doing breast enhancements, one of which was using body fat. While I haven't researched this method, I assume ...
4
votes
1answer
81 views

Synthesis of Fatty Acids Longer than 16 Carbons

I understand that the human body when performing Fatty Acid Synthesis can synthesize only until C16 (palmitate). However the ER has desaturases and elongases. I know that desaturases are used to add ...
3
votes
1answer
57 views

What are the benefits of statins in terms of prolonging life?

Recently the UK government suggested that all adults over the age of 50, without exception, would benefit from taking statins. I have an elderly female relative who may, or may not have had a minor ...
2
votes
1answer
245 views

naturally occuring fatty acids

The double bonds in naturally occurring fatty acids present in our body are in cis configuration while the enzymes for beta oxidation can act on trans double bond. Then what will be the significance ...
4
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0answers
117 views

Why are Mammals are unable to produce Essential Fatty Acids?

Why do we have to get them from our diet, and if they aren't taken in our diet we will face disease? Then why we don't have the enzymes which are require for EFA synthesis?
2
votes
1answer
90 views

What is inside IDL (intermediate density lipoproteïn)?

I am studying about the endogene lipidcycle in the human body and I know that VLDL (very low density lipoproteïn) is made in the liver and that it contains triglycerides and cholesterol from your food ...
2
votes
1answer
233 views

Fatty Acid Synthesis

I have a problem in my reasoning on the fatty acid synthesis in the human body. In the synthesis process you have this homodimer. So the synthesis starts with the transfer of a acetyl group from ...
1
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0answers
59 views

Vitamin D oral intake, transportation and absorption

Several factors affecting vitamin D and its active form absorption and storage acidity of stomach (not significant effect) cytopathic effects of viruses cytopathic effects of bacteria where the ...
8
votes
1answer
6k views

What is/are the molecular differences between HDL and LDL cholesterol?

Why exactly is HDL-cholesterol good for us and LDL-cholesterol bad for us. It has been well-established that LDL-cholesterol is associated with atherosclerosis and that HDL-cholesterol helps remove ...