A series of DNA bases in a chromosome that codes for a poly-peptide sequence.
7
votes
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60 views
paralogue genes in genome-wide association studies?
Has anybody tested if there is an over-representation of significant paralogous copies of genes -- either tandemly-arranged or in different chromosomes -- in the list of significantly associated genes ...
0
votes
0answers
16 views
best known indexing method / transformation to coordinates for gene sequences
What would be the best known method to transform a gene or proteine sequence to some coordinate space (so $t(G)$ is the transformed sequence) complying to following rules:
similar sequences ...
0
votes
0answers
34 views
Confusion related to the use of PCA to determine the background network
I was reading this paper related to use of gene expressions for predicting the drug response. I have this confusion, the paper has used PCA on the covariance matrix formed by the genes to get what is ...
