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0
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2answers
28 views

What amount of genes co-expressed should be expected in a tissue?

I am working with gene expression microarrays of tumor tissues and I want to use a program to find the clusters of co-expressed genes in order to know if some particular genes are co-expressed with ...
0
votes
1answer
43 views

Get Parent GO terms of GO term vector?

I have a vector of GOIDs that are specific GO IDs outputted from an enrichment analysis. I want to cluster my GOIDs by their parent GOID term. I used GOstats to do my enrichment analysis, and I have ...
0
votes
1answer
20 views

Genomic distribution of tRNAs in eukaryotes

The title says it all. I'm doing a literature search trying to see what is widely known and/or well established. I've found a couple of mentions that tRNAs are dispersed throughout the entire nuclear ...
0
votes
1answer
57 views

Critical discussion: Gene expression and systems biology allows us to understand the control of complex traits

I'm having a bit of trouble tackling this question. Any help on what I should write about or the points I should mention would be much appreciated. I keep seeing articles about eQTL and QTL are these ...
4
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0answers
97 views
+50

Why does human chromosome 19 have the second highest number of protein-coding genes?

While chromosome 19 only is the 19th largest autosomal chromosome, it contains 1440 protein-coding genes, and thus has the second highest number of protein-coding genes of any human chromosome. For ...
2
votes
0answers
59 views

CRISPR Knock in

Using the CRISPR/Cas9 technology, it is possible that after inducing a DSB with the Cas9 endonuclease guided with an RNA designed by the user and using a template DNA, get a desired Knock-In (KI) by ...
1
vote
0answers
55 views

How to find name of the gene

Considering the kegg page, this page contains the description of the gene Edwardsiella tarda EIB202: ETAE_0074 . Now this gene has a name given in the page as : wabG. Now considering another gene 1 ...
1
vote
0answers
83 views

How to identify a pseudogene to a specific protein coding genes?

Pseudogenes are those sequences in the genome that bear similarity to specific protein coding genes, but nevertheless are unable to produce functional proteins due to existence of frameshifts, prema- ...
1
vote
0answers
23 views

GO term for orthologous gene IDs

I have a list of orthologous gene IDs from the first supplementary file in here. The gene IDs are of the following type: ...
1
vote
0answers
39 views

His Tag location in gene circuit

I am part of an undergraduate research group and we are trying to produce a protease in an E.coli gene circuit. We are not sure where to place the His tag in our circuit. The sequence is ...OmpA(gene)-...
1
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0answers
30 views

Immediate Early Genes during sleep

In Neuroscience 3rd ed by Bear et al. on page 607, immediate early genes are described as related to changing synaptic strength, yet have decreased expression during sleep. The explanation given is ...
0
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0answers
22 views

Bio Project, Housekeeping promoters, high C-G count, vs tissue specific?

I have a research biology project to do, one part that I'm doing is essentially comparing the sequences of different organisms and based on the sequences am describing whether that gene has a ...
0
votes
0answers
5 views

Delta Mye and F/F after gene name

What do the delta Mye and F/F mean? For example in the following figure (https://www.researchgate.net/figure/45695903_fig5_Figure-2-Enhanced-plasma-inflammatory-cytokines-in-GRK2mye-mice-Mice-were-...
0
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0answers
13 views

Gene Therapy for P50 mutations

I was wondering if it is possible to use gene therapy to fix mutations in the p50 gene. I know this gene when mutated leads to various forms of cancers, so can gene therapy be used to fix this? Or are ...
0
votes
0answers
20 views

Organ secretions

If an animal secrets an enzyme from an organ that is entirely dedicated for the same secretion, can one or cannot one just use the gene coding for that protein to obtain the protein in vitro. How much ...
0
votes
0answers
37 views

minimum ratio of the shortest isoform to the longest one derived from one same parent gene

I want to know what is the minimum percentage of the shortest isoform/transcript to the longest one that derived from the same parent gene? Does it have organism specificity? What is the function of ...