Genetics is the branch of biology that deals with the transmission and variation of inherited characteristics.

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How are 23 chromosomes in human sperm chosen?

I'm not biologist and I have just a basic knowledge. I've been thinking for a long time about the following question: How does the body choose which 23 chromosomes should be active in human sperm and ...
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11 views

What are the forms of host pathogen interaction [on hold]

What are the forms of host pathogen interaction apart from the host pathogen protein protein interaction?? Or is protein protein interface is the only one way of host pathogen interaction?? I am ...
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35 views

What are the white spots?

What are these white spots? It's like Braille writing or something. How is the appearance encoded in the plant? (which I think is a Pine, though I am not sure).
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2answers
50 views

What are the major causes of mutations in DNA?

I know that point mutations can change the base sequence of a gene by altering a specific codon that codes for a particular amino acid. Are these mutations purely random events that occur when DNA is ...
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1answer
19 views

Which is a more profitable feature: codominant or a incomplete dominant feature [closed]

If we want to have as much as possible red flowers, in which case we would be more successful: when the color of flower is a codominant or a incomplete dominant feature? We have only learned the ...
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41 views

How does the size of insert affects the rate of Homologous Recombination in yeast?

When performing genetic knockouts in yeast using homologous recombination to replace a target gene sequence via a vector DNA, does the region between the flanking regions in the vector have to be the ...
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99 views

A good textbook on GMO

I am interested in learning about GMO. The topic is so wrapped in controversy, that it's hard to find a good book that introduces the basic concepts involved. I went through various university ...
2
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1answer
40 views

Genetic abscence of backpain among teen girls? [closed]

I heard a study somewhere (I can't remember where) that claimed that teenage girls are genetically absent to experience high degrees of backpain, specifically from rigorous exercise. Strangely, of ...
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3answers
41 views

Why crossing over don't happen in mitosis?

I mean if there would be crossing over in mitosis then there would various nature of somatic cells. May be that's the logic,but what is the mechanism?why there is no crossing over in mitosis? Does ...
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1answer
41 views

Core architecture of the body encoding [closed]

First of all, I am not a biology guy; I am in Computer Science. But, I have a strong interest in all the mysteries of nature, from universe to human body. So, I want to ask a question related to ...
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2answers
43 views

Lyonization vs Genetic Imprinting

Lyonization is the process in which there is inactivation of an X chromosome in females. This process is implicated in mosaic forms of turner's syndrome (in this case the altered ...
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2answers
45 views

Can genetically engineering the DNA of a human zygote, make it a twin of another human in entirety?

My question is simple. If I wanted to make an exact twin of an individual, will genetically engineering the DNA of the zygote to match with the individual suffice?
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49 views

Can DNA & RNA be considered as nature's programming language?

The final frontier of Biological Sciences could be considered understanding the effects of variation in the DNA (and RNA). If after fertilization the DNA of the zygote could be genetically ...
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41 views

What is the expected number of children that need to be born for every possible point mutation to occur once? [closed]

I'm reading The Perfect Health Diet, and in it the author says that the probability of a point mutation is (175/3*10^9) per new child. He then goes on to write: In the Paleolithic, with 100000 ...
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39 views

How does a baby retain a blood group different from it's mother, in her womb?

It's a well-established fact that blood group is decided by genotype. But, when a new child starts it's journey in the womb, then the mother's blood (along with it's agglutinins and agglutinogens) ...
3
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2answers
71 views

What is biological dark matter?

I recently stumbled upon the Biological Dark Matter wiki page. Its pretty light on details, but it appears to be genetic material found in humans that doesn't fall into currently classifications. ...
4
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49 views

Redheads and pain receptors

I remember reading this in a biology textbook, and decided to do a little digging. Redheads have a lower sensitivity to some pain and a higher sensitivity to other compared to people of other colored ...
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5 views

In insects, does the Alanine repeat occur on the homeodomain sequence of the abdomen or does it occur on a different sequence?

By "Alanine repeat", I am referring to the suppression of the formation of extra insect legs due to Ubx gene suppression through Distal-less repression.
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32 views

DNA barcoding and real-time PCR

I recently read an article on how DNA barcoding was used to identify species present in health products. I also read an article about how Real-Time PCR was used to identify meat species in meat ...
3
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1answer
64 views

What are senescent cells doing in our bodies? [closed]

I'm reading a paper that mentioned the elimination of senescent cells delays aging. I'd like to receive more information about it. The Baker study published in Nature demonstrates that targeted ...
0
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1answer
35 views

Why does the cloning scheme to shuttle GFP into a pL4440 have to be between two T7 promoter regions? [on hold]

When designing a cloning scheme, why does it have to be between the two T7 promoter regions, and what is the benefit of using one or two enzymes to perform this?
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27 views

Why does death exist? [duplicate]

The biological purpose of an organism is to reproduce and as soon as reproductive age is passed, aging kicks in and eventually leads to death. (This is what I learned from a gerontologist.) But then, ...
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32 views

What is the gene regulation behind human adaptation to higher altitudes and therefore higher hemoglobin levels?

Some people in the Amazonian forest and in Himalayan mountains have reported living perfectly with extremely high levels of hemoglobin. I was wondering what type of gene regulation goes on in order ...
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1answer
14 views

How to decide if genes are linked in an unordered mapping problem?

From what I understand, if the tetrads resulting from a cross exhibit the same number of parental ditypes as there are nonparental ditypes, then the genes under consideration are said to be unlinked. ...
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55 views

SNPs and locations

I am new to reading raw DNA. When comparing two people's raw data, why does one person have a different SNP than the other, at the same location, on specific chromosome? But on a different chromosome ...
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48 views

Plasmid in the nucleus and gene expression

If we insert a plasmid into a human nucleus that contains exact copy of gene and all relevant promoters to produce some human protein, will the cell create functional protein from that plasmid only ...
2
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1answer
28 views

Are alleles passed down and shuffled randomly to the offspring during meiosis or fertilization?

If it does occur during meiosis, are the alleles switched over from one sister chromatid to the other during the crossing over process in Prophase I?
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24 views

Basic Gene/Chromosome/Genome/Protein question.. which comes first? [closed]

How are they ordered? Genes make up Chromosome, and Chromosomes make up a Genome... So, where does Protein come into play? What do you call Genes that are spliced together to form something new? ...
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59 views

Crossing white eyed Drosophila with sepia eye

So, I'm doing some drosophila experiments with my high schoolers and I had really poor production of wild type individuals for doing the experiment resulting in not enough to cross with everyone... I ...
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1answer
55 views

Can genetic engineering be performed without a laboratory setting? [closed]

I'm becoming more interested in genetic engineering as I learn more about it, and it's becoming more and more apparent that there's very few resources on genetic engineering at home. A similar ...
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1answer
40 views

How was the origin of CTVT parasitic cancer determined?

The wikipedia article on CTVT says that the tumor cell has 57-64 chromosome while a normal dog has 78 chromosomes. Similarly while all chromosomes in dogs except the X and Y chromosomes are ...
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1answer
64 views

After how many generations descendant is not more related to ancestor, than to a random individual in an ancestral population?

Descendant of n generation has on average 1/2n DNA of ancestor. (For example children have 1/2 DNA of parents and 1/4 DNA of Grandparents, After 10 Generation 1/1024 DNA and after 100 Generations ...
2
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1answer
32 views

Is it possible to estimate how much variation in common phenotypes is predicted by genetics?

Phenotypes such as; skin color, eye color, nose shape, lip size, limb proportions, and skull shape. Im trying to find a source for this quote. "If you ask what percentage of your genes is reflected ...
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1answer
31 views

What is Mendelian Segregation and how is it related to the Hardy-Weinberg equilibrium?

I can't find the exact definition of Mendelian segregation. In addition, I am wondering how it is related to the Hardy-Weinberg equilibrium?
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Could we engineer humans to behave like insects? [closed]

First off, though complex, I'm assuming insects are at an earlier evolutionary stage than humans. That being said, could humans be genetically engineered to behave like insects? I'm not talking about ...
6
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182 views

why is DNA antiparallel? Can it be parallel?

My biology textbook mentions that DNA is antiparallel and it got me wondering... Can DNA be parallel? What would happen if it was parallel? could DNA still replicate right?
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52 views

Known ways to modify the genetic structure of the 13 loci used in CODIS

After reading the answer to Does our DNA change during our lives?, I was wondering if and how it would be possible to change the structure of the 13 loci that are used in the CODIS database, in such a ...
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25 views

What log transformation and normalization functions are most commonly used for microarray and how to select them?

Need help on rational approach to choosing log transformation, standartization and normalization functions in microarray experiments. I am using Expander software and it provides Log2 transform and ...
0
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1answer
35 views

What to do if microarray t-test, ANOVA, SAM and LImma show various selected significant genes?

Need advice: how to approach discrepancy in differential microarray gene expression test results: what to do if ANOVA, ttest, SAM and Limma procedures show different results and especially more ...
4
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476 views

Father with mutated gene for mtDNA- why isn't his offspring at risk?

Mothers transmit their mitochondria (and therefore mtDNA) to their offspring and fathers don't. Lets assume that father had a mutation of the gene that encodes mtDNA, would then be his offspring at ...
5
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1answer
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Are there ways to speed up the growth of plants?

I'm interested in what humans can do to speed up the rate of growth in a plant. I'm interested in both the context of home gardening and large-scale, institution-backed projects. Obviously, optimal ...
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23 views

Is this description of etiology of celiac disease correct?

There is a detailed and, to my inexpert eyes, plausible description of the etiology of celiac disease and other autoimmune disorders posted here: http://no-gluten.org/CeliacDisease.htm Is it is at ...
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Double stranded is more 'durable' than single stranded stuff?

I'm struggling with a question I've been asked. "Why is double stranded genetic material more 'durable' than single stranded one?" I know that double stranded genetic material is more stable due to ...
7
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1answer
89 views

Why is an allele dominant or recessive? [duplicate]

Alleles refer to duplicate genes, where one allele can be dominant over the other. What makes an allele dominant or recessive, given that both code for a single protein?.
3
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2answers
44 views

What does the gene name “lexA” stand for?

It is an important gene expressed in E. coli that represses the SOS response and also the expression of lambda lytic phase genes. UV light and damage to DNA is responsible for its breakdown and hence ...
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1answer
29 views

When do the spindle fibers attach to the chromosome

At what phase does this occur in mitosis (or even meiosis); some text books say prophase while others say metaphase.
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33 views

Is probability for double crossing over included in distance cM? [task]

We got this task: There are 3 genes (acb) on one chromosome (linked inheritance). Distance a-c = 12cM, a-b=16cM. Probability for double crossing-over (CO) is 0,6%. Find ratio of genotypes of ...
0
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1answer
53 views

Supercomputer and undergraduates [closed]

Is it common for an undergraduate to run their thesis (evolutionary genomics) in a supercomputer? In my country, few supercomputers exist, but I'm not sure how it is for bachelors in the US or Europe. ...
3
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1answer
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Why isn't the insertion of a single nucleotide destructive for DNA?

As far as I know proteins are built by sequentially reading triplets of nucleotides. But if at a certain point a nucleotide is inserted in the sequence, the following sequence of triplets is ...
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Why is mRNA needed in the Protein translation?

The original question was to predict the basic requirements for information storage. Then the discussion moved to why is it necessary to include mRNA in the protein translation process. Why can't ...