Tagged Questions
2
votes
1answer
42 views
What is the point of being selection-free?
I'm reading "Highly efficient endogenous human gene correction using designed zinc finger nucleases" by Urnov et al. They propose a way to use zinc finger proteins for gene therapy. They repeatedly ...
4
votes
1answer
199 views
Genetic engineering for insulin production
In order to put human DNA inside a bacteria in order to have it create Insulin, from what type of cell would you need to take the gene for insulin?
I thought it should be from any somatic cell, since ...
4
votes
1answer
120 views
Non-monotonic knock-out effects in prokaryotes
Typically, when performing gene-knockout, the experimenters select one gene to remove/replace-with-junk and then see if the prokaryote can still undergo fission. If it continues to reproduce then the ...
7
votes
0answers
57 views
paralogue genes in genome-wide association studies?
Has anybody tested if there is an over-representation of significant paralogous copies of genes -- either tandemly-arranged or in different chromosomes -- in the list of significantly associated genes ...
14
votes
4answers
1k views
How many genes do we share with our mother?
Somewhere I have read we share more than 99% of our genes with every other other person and 98% of our genes with chimpanzees. What does this mean? Don't we share 50% of our genes with our mother and ...
21
votes
4answers
250 views
How are the boundaries of a gene determined?
What statistical processes and methods are used by geneticists/molecular biologists to know where one gene starts and one ends?
