Genetics is the branch of biology that deals with the transmission and variation of inherited characteristics.

learn more… | top users | synonyms

0
votes
1answer
37 views

Current state of Gene Therapy

I am interested in learning about attempts to treat adult individuals suffering from a genetic disease in which the underlying changes in the DNA of the gene are understood. (i) Are there approaches ...
-2
votes
2answers
46 views

What are sex linked traits?

Which of the two definitions of sex-linked trait is correct? Traits controlled by genes present on the non-homologous region of sex chromosomes are called ...
16
votes
4answers
2k views

Book recommendation on population/evolutionary genetics?

I have recently been involved in collaborations that require me to model the population genetics of eukaryotic populations. I fear I may either be "re-inventing the wheel" or making conceptual ...
2
votes
1answer
69 views

Ancestral Allele and Hapmap

I notice on dbSNP rs6352 has an ancestral allele of G - http://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?rs=rs6352 The hapmap in humans for this allele is very rare, the homozygous version practically not ...
12
votes
5answers
18k views

Do we get 1/4 of our genes from each grandparent?

I know that we get half of our genes from each parent, but does it necessarily mean we get 1/4 of our genes from each grandparent? Or is it possible that we might get say 30% from one grandparent, 20% ...
-2
votes
1answer
23 views

What are silent carrier traits?

I couldn't find a definition but I have come to know the following from google search: People who are carriers of a thalassemia gene show no thalassemia symptoms and might not know they're ...
0
votes
0answers
15 views

Links between Genetics and Personality Types

This topic was visited briefly in the thread, Genetic Effects on Personality, but I was surprised not to find more on it. (Is there a taboo I don't know about? What's the ethical stance on this ...
3
votes
2answers
38 views

Mutating a protein without mutating the gene?

Is it possible to mutate a region of a protein (says about 300 amino acids long) without actually mutating the gene? One possible way that I can think of is to use RNAi and specifically block that ...
4
votes
1answer
150 views

Non-monotonic knock-out effects in prokaryotes

Typically, when performing gene-knockout, the experimenters select one gene to remove/replace-with-junk and then see if the prokaryote can still undergo fission. If it continues to reproduce then the ...
0
votes
0answers
11 views

Lyonization and Turner's syndrome

If lyonization is basically inactivation on X chromosome, and Turner's syndrome patients have only one existing X chromosome, what is the difference between healthy women with inactivated X chromosome ...
3
votes
1answer
649 views

Can DNA & RNA be considered as nature's programming language?

The final frontier of Biological Sciences could be considered understanding the effects of variation in the DNA (and RNA). If after fertilization the DNA of the zygote could be genetically ...
0
votes
2answers
556 views

3 flaws of genes from the perspective of a programmer [on hold]

Having a double helix structure seems like a waste of space. In programming you would have a single array and just before mitosis you would double the single helix. Having an exact copy of a ...
0
votes
1answer
35 views

What are Codominant vs Dominant Genetic Markers?

When talking about types of genetic markers, the adjective "dominant" and "codominant" are often used. I don't fully understand their definitions and found contradicting definitions. Foll and ...
0
votes
1answer
35 views

A doubt on Introgression

Wikipedia says that Introgression, also known as introgressive hybridization, in genetics is the movement of a gene (gene flow) from one species into the gene pool of another by the repeated ...
0
votes
0answers
37 views

Can the DNA of 2 women create a child? Chimera [on hold]

Imagine a woman and a man creating a child. The man is in fact a chimera whose unborn twin was a female. Is it possible that some of the spermatozoids of the man contain DNA of only the unborn female ...
0
votes
0answers
23 views

How does epigenetics affect the birth conditions via alcohol?

Recent study has shown that epigenetics can play role in male-caused infertility and it cites for example studies which showed an enhancing of silent genes when drinking alcohol. Since the study ...
4
votes
2answers
94 views

Is it possible to have different genes in different parts of our body?

I want to understand genetic mutation specially in the context of multicellular organisms like humans. I studied biology only till high school and I can’t fully understand wikipedia pages on this ...
-1
votes
2answers
29 views

What is gene density?

As per wikipedia definition, gene density is defined as: "In genetics, the gene density of an organism's genome is the ratio of the number of genes per number of base pairs, usually written in ...
0
votes
1answer
14 views

Statistical genetics: Allele frequencies that follow a Dirichlet distribution

From Foll and Gagiotti (2008) (software BayeScan). They consider a model where several subpopulation are derived from a unique ancestral population. We consider a set of $I$ loci and let $K_i$ be ...
1
vote
1answer
29 views

Why do mutations in Drosophila dsx (double sex) affect both males and females?

Reason: Loss-of-function mutation of dsx gene in female embryo leads to production of a nonfunctional protein that fails to repress male specific gene expression. So somatic characters of both the ...
0
votes
1answer
33 views

Given the number of individuals who have a recessive disorder, how can one calculate the probability that the disorder was inherited? [on hold]

Just to be clear, this is not homework. Suppose a biological family has five children, two of whom have a certain recessive genetic disorder that is not sex-linked. The parents themselves do not have ...
0
votes
1answer
35 views

Mendel Genetics: Homework question

I'm looking at a question right now about Mendel genetics..... Q) When Mendel crossed a large number of tall pea plants with short pea plants, all F1 plants were tall. The F2 generation was created ...
1
vote
1answer
64 views

Standard notation for dominant and recessive allele

I'm reading through some science that could come up in my GRE equivalency. I've never been much of a biologist, more of a chemist/geologist....though it does interest me massively! I'm just seeing ...
4
votes
4answers
217 views

Gametes of two different species

I always wondered why gametes from two different species dont fuse together to form an offspring. eg a donkey (sperm) and a female dog (egg) I know this is not possible but I'm just curious.
1
vote
2answers
36 views

When was the first exception to Mendelian genetics discovered?

In addition to the the question in the title I'd like to know , how scientists reacted to the exceptions?
1
vote
1answer
22 views

Methods for varying insert size in E. coli clones

I'm writing my master's thesis proposal, and I need to improve the solution-behavior of some truncated protein domains which have previously shown poor solubility when expressed in E. coli. To ...
2
votes
0answers
34 views

Do trees have genes for stopping the grow?

Do trees have genetically encoded to stop growing at some height, to keep dividing the cells only to a certain amount, or to pump nutritions only till it's advantageous because they've already ...
0
votes
1answer
31 views

Why does meiotic recombination disrupt the independent assortment of genes on the same chromosome?

There are many sources that say that genes that are "linked" by being on the same chromosome assort with each other -- that when an allele is passed on that the gamete containing said allele will also ...
3
votes
1answer
52 views

Is there selection against long proteins and long genes?

Background thought Titin and TTN Titin is the largest protein in the human genome with 33423 amino acids. Titin is coded by the gene TTN that must be at least $3 \cdot 33423 \approx 100kb$ long. ...
1
vote
1answer
53 views

autosomal recessive population numbers

This question is background research for a science fiction / fantasy novel, my knowledge of genetic is very basic. It seems obvious to me that for genetic disorders that are autosomal recessive, if ...
-1
votes
0answers
48 views

Does the Anthony Walsh book “Is Race a Socially Dangerous Idea” have biological merit?

Preface: I'm not a biologist asking this question, but I do find this curious. I was reading Science Wars by Anthony Walsh, and in a chapter titled "Is Race a Socially Dangerous Idea" he outlined the ...
0
votes
2answers
50 views

Genetics - Ancestry DNA relationships

If my uncle and I both got our DNA tested and compared ancestry results, should we have 50% or 25% similarity? I get normally it would be 25% but since the mitochondrial DNA and Y chromosome are ...
1
vote
1answer
61 views

How do harsh conditions cause an increase in the male birth ratio?

I've heard that in harsh conditions more human baby boys are born than girls because a bigger ratio of them will die before reproductive age. But in which aspects of the random gene combination while ...
1
vote
0answers
21 views

What tell a plant to have one/a lot of flower(s)? [closed]

some plants just have one flower and some have more. This is the question. please simply tell me how? which genes or pathways control this in various plants?
4
votes
0answers
40 views

How do chromosome pairs get “paired up” for protein synthesis?

If my understanding is correct, during interphase a normal human cell will have 46 chromosomes scattered about in the cell nucleus. These chromosomes can be thought of as pairs: there are two copies ...
7
votes
1answer
88 views

Can a Turner syndrome patient develop male characteristics artificially?

From an answer to the question Can stem cells from male convert to cells of female-only organs, and vice versa? Y chromosome is the sex determining chromosome with SRY gene that determines testes ...
1
vote
0answers
25 views

Mendelian genetics - How can we infer the number of genes in play in this scenario?

So this is a practice question I got from school but I kinda lost here. So the question is: In Drosophila , four new recessive mutations have been found all of which produce purple eye ...
4
votes
0answers
68 views

Does Cas9 require a nuclear localization signal (NLS) for it to work in a Eukaryote?

I'm trying to establish if it's required to add a NLS to Cas9 when expressed (or transfected) in a Eukaryotic cell. Several papers report using a viral NLS, but is it absolutely necessary? Could ...
1
vote
2answers
52 views

Recessive is Dominant to Dominant?

If a gene has for instance three alleles, p, q, and r, then could p be dominant to q, q be dominant to r, but r be dominant to p? Can a gene that is recessive to one allele not be dominant to another ...
1
vote
0answers
26 views

Why would worker bias sex-ratio toward workers?

This question prompts for explanation on a topic, an interpretation of this topic is given. A simplified question statement is also given at the end for those who do not wish to read. Topic In the ...
0
votes
1answer
39 views

How does epigenetics know to mutate which gene in order to survive? [closed]

It seems that during reproduction particular genes are targeted for modification (mutation, deletion, insertion, etc.) given environmental inputs of either or both of the parents. If a creature was ...
2
votes
1answer
73 views

Pink Grasshoppers

The area I found this grasshopper was Canyon Country, California, USA In a desert/field area. I have been reading up on grasshoppers because I recently came into possession of a pink grasshopper (It ...
3
votes
3answers
40 views

Difference between null and recessive allele?

I get that in a single gene locus, an individual can have RR, Rr, or rr as the two alleles ...
1
vote
1answer
25 views

Is there any clear relationship between physical characteristics and patterns in the genome?

Given that for example humans have five fingers on each hand, is there a region in the genome with a sequence of five similar subregions, one for each finger? Is the region on the genome that encodes ...
1
vote
1answer
35 views

Why must DNA be packed into chromosomes during mitotic phase?

Why does DNA have to be packed into chromosomes? Why can't DNA just divide itself evenly?
1
vote
1answer
38 views

Is it possible to remove one strand of double stranded DNA in vivo?

Assume we do have a double stranded DNA sequence in human cells, say ...ATCGATATCGATATTGCAGAGCATAGCTATAA... ...TAGCTATAGCTATAAGCTCTCGTATCGATATT... Now I want to ...
8
votes
3answers
189 views

Are non-coding RNAs introns?

I am slightly confused as to what part of the genome codes for non-coding RNAs. Is it the introns? This would make sense to me as to why they are not transcribed as the introns are not transcribed. Or ...
4
votes
2answers
59 views

Do only one or both pairs of homologous chromatids exchange genetic material during the process of crossing over?

To be specific: Assume chromosomes A and B are homologous. They've both replicated into A1, A2 and B1, B2 and have formed a tetrad at the equator (synapsis). Most textbooks show either A1 and B1 OR A2 ...
1
vote
1answer
35 views

Relationship between genetic diversity within and between species

Here is a quote from Wagner (2008) A second line of evidence [against neutralism] comes from the relationship between the mean number of polymorphic differences between alleles within a species, ...
-1
votes
1answer
49 views

Has anyone done a GCTA of leg length? [closed]

There is extensive genomic research on height, but nobody seems to have done a gcta of leg length.