Genetics is the branch of biology that deals with the transmission and variation of inherited characteristics.

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Lac operon: How can lactose enter the cell in the absence of lactose permease?

My textbook states that lactose permease...transports lactose into the cell and When lactose is added to the growth medium, the lactose molecules bind to the other site on the repressor ...
2
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1answer
104 views

How to retrieve logical expression (KO based) for reactions from KEGG?

Whether a module is complete or not can easily be checked by evaluating the Definition entry associated with the module; e.g. in module M00010, it is given by <...
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1answer
32 views

Distribution of Exon and Intron Sizes

Goal I am trying to get a distribution of Exons and intron sizes in Three-Spined Stickleback (Gasterosteus aculeatus). Data downloaded I downloaded some data from Ensembl. More precisely, I went ...
3
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2answers
60 views

Mutating a protein without mutating the gene?

Is it possible to mutate a region of a protein (says about 300 amino acids long) without actually mutating the gene? One possible way that I can think of is to use RNAi and specifically block that ...
4
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2answers
162 views

Redundancy of the genetic code

One particular codon codes only for one amino acid, but an amino acid can be coded for by several different codons. Now according to the genetic code, the codon UUU ...
2
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1answer
1k views

Definition and example of Gene Variant

Could someone clearly define what a gene variant is with an example. I am totally confusing myself with SNPs, alleles, variants and how the major and minor allele are defined. An example with gene ...
0
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2answers
21 views

What is the genetic difference between two cone branches?

As we can see on this larch, male and female cones are sometimes directed to grow on the opposite side of the branch. We were told in school that this mechanism works against self-fertilization. Also ...
0
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0answers
16 views

What do recessive/dominant alleles actually mean in terms of modern genomics? [duplicate]

In Mendelian genetics, we discuss phenotypes, which are specified by the alternative versions of genes called alleles. In terms of peas, the phenotype "round pea" encoded by one allele of a gene is ...
0
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1answer
46 views

Current state of Gene Therapy [closed]

I am interested in learning about attempts to treat adult individuals suffering from a genetic disease in which the underlying changes in the DNA of the gene are understood. (i) Are there approaches ...
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2answers
74 views

What are sex linked traits?

Which of the two definitions of sex-linked trait is correct? Traits controlled by genes present on the non-homologous region of sex chromosomes are called sex-...
2
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1answer
71 views

Ancestral Allele and Hapmap

I notice on dbSNP rs6352 has an ancestral allele of G - http://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?rs=rs6352 The hapmap in humans for this allele is very rare, the homozygous version practically not ...
12
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5answers
18k views

Do we get 1/4 of our genes from each grandparent?

I know that we get half of our genes from each parent, but does it necessarily mean we get 1/4 of our genes from each grandparent? Or is it possible that we might get say 30% from one grandparent, 20% ...
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1answer
37 views

What are silent carrier traits? [closed]

I couldn't find a definition but I have come to know the following from google search: People who are carriers of a thalassemia gene show no thalassemia symptoms and might not know they're ...
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0answers
18 views

Links between Genetics and Personality Types

This topic was visited briefly in the thread, Genetic Effects on Personality, but I was surprised not to find more on it. (Is there a taboo I don't know about? What's the ethical stance on this ...
4
votes
1answer
150 views

Non-monotonic knock-out effects in prokaryotes

Typically, when performing gene-knockout, the experimenters select one gene to remove/replace-with-junk and then see if the prokaryote can still undergo fission. If it continues to reproduce then the ...
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0answers
20 views

Lyonization and Turner's syndrome

If lyonization is basically inactivation on X chromosome, and Turner's syndrome patients have only one existing X chromosome, what is the difference between healthy women with inactivated X chromosome ...
3
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1answer
664 views

Can DNA & RNA be considered as nature's programming language?

The final frontier of Biological Sciences could be considered understanding the effects of variation in the DNA (and RNA). If after fertilization the DNA of the zygote could be genetically ...
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2answers
586 views

3 flaws of genes from the perspective of a programmer [closed]

Having a double helix structure seems like a waste of space. In programming you would have a single array and just before mitosis you would double the single helix. Having an exact copy of a cromatid. ...
0
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1answer
61 views

What are Codominant vs Dominant Genetic Markers?

When talking about types of genetic markers, the adjective "dominant" and "codominant" are often used. I don't fully understand their definitions and found contradicting definitions. Foll and ...
0
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1answer
35 views

A doubt on Introgression

Wikipedia says that Introgression, also known as introgressive hybridization, in genetics is the movement of a gene (gene flow) from one species into the gene pool of another by the repeated ...
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0answers
23 views

How does epigenetics affect the birth conditions via alcohol?

Recent study has shown that epigenetics can play role in male-caused infertility and it cites for example studies which showed an enhancing of silent genes when drinking alcohol. Since the study ...
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2answers
35 views

What is gene density?

As per wikipedia definition, gene density is defined as: "In genetics, the gene density of an organism's genome is the ratio of the number of genes per number of base pairs, usually written in ...
0
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1answer
17 views

Statistical genetics: Allele frequencies that follow a Dirichlet distribution

From Foll and Gagiotti (2008) (software BayeScan). They consider a model where several subpopulation are derived from a unique ancestral population. We consider a set of $I$ loci and let $K_i$ be ...
0
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1answer
33 views

Given the number of individuals who have a recessive disorder, how can one calculate the probability that the disorder was inherited? [closed]

Just to be clear, this is not homework. Suppose a biological family has five children, two of whom have a certain recessive genetic disorder that is not sex-linked. The parents themselves do not have ...
1
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1answer
69 views

Standard notation for dominant and recessive allele

I'm reading through some science that could come up in my GRE equivalency. I've never been much of a biologist, more of a chemist/geologist....though it does interest me massively! I'm just seeing ...
4
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4answers
218 views

Gametes of two different species

I always wondered why gametes from two different species dont fuse together to form an offspring. eg a donkey (sperm) and a female dog (egg) I know this is not possible but I'm just curious.
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2answers
38 views

When was the first exception to Mendelian genetics discovered?

In addition to the the question in the title I'd like to know , how scientists reacted to the exceptions?
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1answer
22 views

Methods for varying insert size in E. coli clones

I'm writing my master's thesis proposal, and I need to improve the solution-behavior of some truncated protein domains which have previously shown poor solubility when expressed in E. coli. To ...
2
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0answers
40 views

Do trees have genes for stopping the grow?

Do trees have genetically encoded to stop growing at some height, to keep dividing the cells only to a certain amount, or to pump nutritions only till it's advantageous because they've already ...
3
votes
1answer
55 views

Is there selection against long proteins and long genes?

Background thought Titin and TTN Titin is the largest protein in the human genome with 33423 amino acids. Titin is coded by the gene TTN that must be at least $3 \cdot 33423 \approx 100kb$ long. ...
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1answer
53 views

autosomal recessive population numbers

This question is background research for a science fiction / fantasy novel, my knowledge of genetic is very basic. It seems obvious to me that for genetic disorders that are autosomal recessive, if ...
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2answers
55 views

Genetics - Ancestry DNA relationships

If my uncle and I both got our DNA tested and compared ancestry results, should we have 50% or 25% similarity? I get normally it would be 25% but since the mitochondrial DNA and Y chromosome are (...
1
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1answer
64 views

How do harsh conditions cause an increase in the male birth ratio?

I've heard that in harsh conditions more human baby boys are born than girls because a bigger ratio of them will die before reproductive age. But in which aspects of the random gene combination while ...
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0answers
23 views

What tell a plant to have one/a lot of flower(s)? [closed]

some plants just have one flower and some have more. This is the question. please simply tell me how? which genes or pathways control this in various plants?
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0answers
44 views

How do chromosome pairs get “paired up” for protein synthesis?

If my understanding is correct, during interphase a normal human cell will have 46 chromosomes scattered about in the cell nucleus. These chromosomes can be thought of as pairs: there are two copies ...
7
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1answer
88 views

Can a Turner syndrome patient develop male characteristics artificially?

From an answer to the question Can stem cells from male convert to cells of female-only organs, and vice versa? Y chromosome is the sex determining chromosome with SRY gene that determines testes ...
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0answers
26 views

Mendelian genetics - How can we infer the number of genes in play in this scenario?

So this is a practice question I got from school but I kinda lost here. So the question is: In Drosophila , four new recessive mutations have been found all of which produce purple eye ...
4
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0answers
78 views

Does Cas9 require a nuclear localization signal (NLS) for it to work in a Eukaryote?

I'm trying to establish if it's required to add a NLS to Cas9 when expressed (or transfected) in a Eukaryotic cell. Several papers report using a viral NLS, but is it absolutely necessary? Could ...
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2answers
52 views

Recessive is Dominant to Dominant?

If a gene has for instance three alleles, p, q, and r, then could p be dominant to q, q be dominant to r, but r be dominant to p? Can a gene that is recessive to one allele not be dominant to another ...
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0answers
27 views

Why would worker bias sex-ratio toward workers?

This question prompts for explanation on a topic, an interpretation of this topic is given. A simplified question statement is also given at the end for those who do not wish to read. Topic In the ...
3
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1answer
84 views

Pink Grasshoppers

The area I found this grasshopper was Canyon Country, California, USA In a desert/field area. I have been reading up on grasshoppers because I recently came into possession of a pink grasshopper (It ...
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3answers
43 views

Difference between null and recessive allele?

I get that in a single gene locus, an individual can have RR, Rr, or rr as the two alleles ...
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1answer
25 views

Is there any clear relationship between physical characteristics and patterns in the genome?

Given that for example humans have five fingers on each hand, is there a region in the genome with a sequence of five similar subregions, one for each finger? Is the region on the genome that encodes ...
8
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3answers
217 views

Are non-coding RNAs introns?

I am slightly confused as to what part of the genome codes for non-coding RNAs. Is it the introns? This would make sense to me as to why they are not transcribed as the introns are not transcribed. Or ...
1
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1answer
36 views

Relationship between genetic diversity within and between species

Here is a quote from Wagner (2008) A second line of evidence [against neutralism] comes from the relationship between the mean number of polymorphic differences between alleles within a species, $\...
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1answer
60 views

Has anyone done a GCTA of leg length? [closed]

There is extensive genomic research on height, but nobody seems to have done a gcta of leg length.
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24 views

Dihybrid Cross Help Please

lobe eyes female x crossveinless wing male F1 Progeny: Female lobe eyes: 5023 Male Lobe eyes: 4931 F2 progeny: Female wild: 1241 Male wild:630 Female lobe eyes:3803 Male lobe eyes:1892 ...
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4answers
239 views

Is there any other function of DNA?

We all know that DNA acts as a genetic molecule. Does DNA have any other function in the cell other than being a genetic material and carrier of information?
4
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2answers
77 views

Is there a term for when a detrimental gene can be positively selected for because of linkage to a very fit gene?

Let's say that some piece of DNA would be subject to extreme negative selection if it were independently inherited, but it is very closely linked to an extraordinarily fit gene, and so the complex it ...
0
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1answer
23 views

Cell division - meiosis

Really confused. How many chromosomes pairs do humans have in their sex cells? How many single chromosomes do humans have in their sex cells?