Genetics is the branch of biology that deals with the transmission and variation of inherited characteristics.

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Is there any other function of DNA?

We all know that DNA acts as a genetic molecule. Does DNA have any other function in the cell other than being a genetic material and carrier of information?
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Is there a term for when a detrimental gene can be positively selected for because of linkage to a very fit gene?

Let's say that some piece of DNA would be subject to extreme negative selection if it were independently inherited, but it is very closely linked to an extraordinarily fit gene, and so the complex it ...
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23 views

Cell division - meiosis

Really confused. How many chromosomes pairs do humans have in their sex cells? How many single chromosomes do humans have in their sex cells?
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71 views

What does characterization mean in a genomics context?

"The resulting libraries of gene sequences allow CDC and other laboratories to compare the genes of currently circulating influenza viruses with the genes of older influenza viruses and viruses ...
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11 views

About Hermaphrodite Mitochondrial Inheritance

From the textbook I've learnt that in general mitochondria are inherited maternally. However if the cross is between hermaphrodites (e.g. in C.elegans), where, in most cases, then should the ...
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58 views

Are there genes in sex chromosomes that determine facial features?

My friends and I were bored enough to try out this activity. Picture a teenage boy in your mind. From this picture, remove any accessories (glasses, piercings, etc.), moustache or beard, then ...
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1answer
51 views

Assuming if height was fully determined genetically, what would be the concordance between monozygotic pairs?

I fully understand the differences between monozygotic and dyzogtic twin pairings, but I wondered how I could put into words the reasons why the concordance would be very high. Derived from same ...
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57 views

What's the exact meaning of and how to derive the coefficient of the path from sire to offspring?

According to Wright's Coefficients of Inbreeding and Relationship, the coefficient of the path from sire to offspring is given as $p_{o \cdot s}=\frac{1}{2}\frac{\sqrt{1+F_s}}{\sqrt{1+F_o}}$ But ...
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147 views

Genetic mutations and new alleles

Amongst silent, nonsense and missense genetic mutations, is the latter the only one that leads to the creation of new alleles? If we define alleles as a specific form of a gene, and a gene as a ...
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950 views

Why would lethal genes evolve?

I've been reading through 'The Selfish Gene' by Dawkins. At a few places in the book he states that incest is damaging because it would give a very high chance of lethal recessive genes becoming ...
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29 views

How to search for all human diseases associated with a inversion on chromosome 22?

Is there any way to search for all diseases that associated with inversions on chr22? I found some online research databases like OMIM and disgenet but I don't know the correct nomenclature on how to ...
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1answer
32 views

What is a “homologous pair” of chromosomes in cross joining or cross over?

I never understand if the chromatids attached at the centromere is a homologous pair, or the male and female chromosomes?
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185 views

Swapping genes?

So, gene therapy is to take out a gene, correct its mutation, and put the corrected one back into the organism, right? Is it also possible to take out a gene from an organism and put in a totally ...
2
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1answer
142 views

Mutation-drift equilibrium and among loci variance in heterozygosity

At mutation-drift balance, the increased heterozygosity brought by new mutations is exactly equal to the loss of heterozygosity due to genetic drift. At equilibrium, the expected heterozygosity for a ...
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20 views

DNA. mRNA, tRNA [closed]

Can someone explain to me how transcription and translation works, especially the part about codes. And does amino acids has code or is it the tRNA?
4
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1answer
304 views

How significant is the genetic component of homosexual behaviour?

From some basic googling, I found that nobody has ever proven that people are born gay and that environment plays a great part in homosexuality. I wish to know if there is a genetic component to ...
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2answers
55 views

CRISPR/Cas for editing the human genome [closed]

I know, that the CRISP/Cas approach for "cutting" the human genome is not completely suitable if we can't say not suitable at all. Because we have many repeats and this approach can bring to our ...
5
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2answers
159 views

Components of the concept of Developmental Noise?

Developmental noise is a concept that correspond to the amount of possible phenotypic variance of a given genotype in a given environment. Intrinsic noise (aka Cellular noise) is a component of ...
4
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1answer
143 views

Are males taller than females?

Is there any scientific evidence that males are taller than females? And the reason why they are taller (please include genes or hormones that accounts for human growth and how they are affected in ...
0
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1answer
78 views

What is the difference between multiple allelism and polymorphism?

Multiple allelism is defined as "the existence of more than two alleles of the same gene within a population." Polymorphism is "the occurrence of more than two distinct phenotypes of a trait in a ...
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1answer
42 views

Deducing amino acid sequence from a DNA sequence

The suggested answer to the question is the following: "M L S C D K S D Stop". I do not understand how they get that result. The question is as follows: An RNA polymerase transcribes the following ...
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23 views

Breeding Southern Right Whales Genetics

I don't know much about biology. I just like watching David Attenborough videos and this made me curious. I just watched this video about breeding Southern Right Whales, and these two quotes puzzled ...
5
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1answer
133 views

How genetically similar are worker ants from the same colony?

I've been reading https://en.wikipedia.org/wiki/Ant and it says If the egg is fertilised, the progeny will be female diploid; if not, it will be male haploid. Since the males have only one set ...
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41 views

What further research can the result of gene variation detection be used for [closed]

We do a research on a particular cancer (for e.g. breast cancer). Now, we have a result for the gene variation detection (VCF file). What next steps do we need to do? We don't have a clear picture ...
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2answers
721 views

Can parents' learned traits be transmitted genetically?

I am wondering whether a behavioral trait (e.g. fear or stress experienced in the lifetime of the parent) can be transmitted genetically to its offspring? I understand that a behavioral tendency for ...
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Dominant model Disease SNP

Say that you have genotyped a SNP in a case control setting, and get the following result AA AB BB Cases 17 51 29 Controls 39 44 20 where A ...
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0answers
22 views

What the gene variation detection result can tell us about a cancer [duplicate]

We do a research on a particular cancer, now we have a result of the gene variation detection . What next steps do we need to do? we don't have a clear picture about this. Can you give us some ...
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36 views

How do biologists quantify “gene expression” in experiments?

I've read papers which contain statements such as "control of gene expression is critical in biological processes". How exactly does one quantify "gene expression"? Isn't gene expression an umbrella ...
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52 views

Population size and genetic drift - What are the evidences?

Wright-Fisher model From the Wright-Fisher model of genetic drift, the random sampling of allele from one generation to the next is taken from a binomial distribution with parameters $2N$ and $p$, ...
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2answers
64 views

Which strand of a gene specifies a protein? [closed]

A gene is a segment of DNA (I hope double stranded) and each strand when transcribed form a mRNA and after being translated a protein. As from each gene there are two proteins that are being formed. ...
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3answers
81 views

Can I figure out the identity of my grandparent from this information? [closed]

I know all my family up to my grandparents, with the exception of the grandfather on my mother's side. At the time my mother was conceived, my grandmother was having an affair so no one in my family ...
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32 views

Can the restless leg syndrome may have been caused due to natural selection? [closed]

Disclaimer: I don't know how much restless the leg has to be, in order to be considered a syndrome. RLS runs not only in my family but also several people in the locality. My hypothesis is that RLS ...
3
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2answers
114 views

Why do some animals try to imitate other animals?

There is a tendency of some animals (including people!) to be "copy-cats" and try to imitate members of their own, and sometimes other, species. The most obvious example is a parrot copying human ...
4
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1answer
60 views

Directed evolution: Point mutation vs Insertion-Deletion vs Shuffling

When attempting enzyme function improvement via Directed Evolution I can see three different strategies to generating variation for the gene sequence: Point mutations Insertion / Deletions Shuffling ...
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3answers
108 views

Relationship of the DNA of a eukaryotic gene to the 5'-UTR of its mRNA

In eukaryote pre-mRNA I am having a little trouble grasping exactly what the 5 prime untranslated region is defined as. It seems that it could be defined as the difference in pre-mRNA between the ...
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34 views

Is there a way to identify a species of tree?

My family has been passing down seeds from a lemon tree for about 3 generations now, There is some controversy about its origin or species. The lemons look like tangerines and when cut the pulp is ...
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14k views

What's the difference between shotgun sequencing and clone based sequencing?

In a lecture during my undergraduate degree we were introduced to the race to complete the human genome. Celera were competing with Sanger and collaborators to sequence the human genome. Celera ...
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1answer
54 views

Data on Gene Position in Human Genome

I am trying to get some data on gene position in the human genome and I need some help What I tried I downloaded ...
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1answer
86 views

Why is an A-U bond less stable than an A-T bond?

I have encountered the following fact many times, but have not yet encountered a possible explanation for it. Will you please help me understand the molecular mechanism by which the bond between ...
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1answer
53 views

How many people in the world have bad eyesight?

I was watching this ted.ed episode and heard it was around 500,000 but that didn't sound right-- does anyone know?
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1answer
48 views

How can a haploid plant be bisexual?

According to Wikipedia: Meiosis is a specialized type of cell division that reduces the chromosome number by half. This process occurs in all sexually reproducing single-celled and multicellular ...
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2answers
71 views

Infer gene frequency within a species over time

I was reading Karlsson et al. (2014) and I came into this: A selected variant that increases rapidly in frequency in the past ~250,000 years can be detected as an unusual reduction in genetic ...
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1answer
41 views

DNA replication : binding

Regarding an activator, does the C amp cap complex, bind to the coding strand, the template strand, or both?
5
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1answer
81 views

Can difference in the expression potential of alleles lead to dominance?

Several hour ago I was in thoughts what allele dominance really means on molecular level. As we know from basic genetics, if the organism had Aa type of some gene ...
2
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1answer
105 views

Could an annual plant be genetically modified to be a perennial?

My chives, asparagus, oregano, and rhubarb come back every year like clockwork. Suppose I want my bok choy to join the party - is there an "I'll be seeing you next year!" gene that can be modified to ...
0
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1answer
22 views

Measuring tumor heterogeneity [closed]

I would like to ask if there's any method (established or not) in order to quantify heterogeneity found in mutations occuring in primary neoplasms and metastatic lesions (either common or private) and ...
3
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2answers
182 views

Are gametes determined by the sex of an organism?

In the Wikipedia article for biological sex, I read the following sentence. "The gametes produced by an organism are determined by its sex:..." However, is it not through the gametes produced by ...
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1answer
42 views

No. of genes in chromosomes. phenotype

Why do cells need all the genes of all the 22 pairs (excluding the 2 X- or Y-chromosomes) of autosomes in every somatic cell, when each and every cell which is specialised for its function does not ...
3
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48 views

Is $F_{ST}$ a probability and a correlation coefficient?

$F_{ST}$ is one of the most famous and most important statistics of all of evolutionary biology. Yet, many people misunderstand it or misuse the classical results from the literature on $F_{ST}$ (...
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26 views

How do genetic logic gates work?

Recently researchers at MIT have developed genetic logic gates which can be built into programs. How do these "genetic logic gates" work? "The language is based on Verilog, which is commonly used to ...