Genetics is the branch of biology that deals with the transmission and variation of inherited characteristics.

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Can genetically engineering the DNA of a human zygote, make it a twin of another human in entirety?

My question is simple. If I wanted to make an exact twin of an individual, will genetically engineering the DNA of the zygote to match with the individual suffice?
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1answer
441 views

Can DNA & RNA be considered as nature's programming language?

The final frontier of Biological Sciences could be considered understanding the effects of variation in the DNA (and RNA). If after fertilization the DNA of the zygote could be genetically ...
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43 views

What is the expected number of children that need to be born for every possible point mutation to occur once? [closed]

I'm reading The Perfect Health Diet, and in it the author says that the probability of a point mutation is (175/3*10^9) per new child. He then goes on to write: In the Paleolithic, with 100000 ...
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70 views

How does a baby retain a blood group different from it's mother, in her womb?

It's a well-established fact that blood group is decided by genotype. But, when a new child starts it's journey in the womb, then the mother's blood (along with it's agglutinins and agglutinogens) ...
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2answers
973 views

What is biological dark matter?

I recently stumbled upon the Biological Dark Matter wiki page. Its pretty light on details, but it appears to be genetic material found in humans that doesn't fall into currently classifications. ...
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127 views

Redheads and pain receptors

I remember reading this in a biology textbook, and decided to do a little digging. Redheads have a lower sensitivity to some pain and a higher sensitivity to other compared to people of other colored ...
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1answer
41 views

In insects, does the Alanine repeat occur on the homeodomain sequence of the abdomen or does it occur on a different sequence?

By "Alanine repeat", I am referring to the suppression of the formation of extra insect legs due to Ubx gene suppression through Distal-less repression.
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2answers
60 views

DNA barcoding and real-time PCR

I recently read an article on how DNA barcoding was used to identify species present in health products. I also read an article about how Real-Time PCR was used to identify meat species in meat ...
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1answer
69 views

What are senescent cells doing in our bodies? [closed]

I'm reading a paper that mentioned the elimination of senescent cells delays aging. I'd like to receive more information about it. The Baker study published in Nature demonstrates that targeted ...
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0answers
30 views

Why does death exist? [duplicate]

The biological purpose of an organism is to reproduce and as soon as reproductive age is passed, aging kicks in and eventually leads to death. (This is what I learned from a gerontologist.) But then, ...
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36 views

What is the gene regulation behind human adaptation to higher altitudes and therefore higher hemoglobin levels?

Some people in the Amazonian forest and in Himalayan mountains have reported living perfectly with extremely high levels of hemoglobin. I was wondering what type of gene regulation goes on in order ...
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1answer
21 views

How to decide if genes are linked in an unordered mapping problem?

From what I understand, if the tetrads resulting from a cross exhibit the same number of parental ditypes as there are nonparental ditypes, then the genes under consideration are said to be unlinked. ...
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59 views

SNPs and locations

I am new to reading raw DNA. When comparing two people's raw data, why does one person have a different SNP than the other, at the same location, on specific chromosome? But on a different chromosome ...
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1answer
89 views

Plasmid in the nucleus and gene expression

If we insert a plasmid into a human nucleus that contains exact copy of gene and all relevant promoters to produce some human protein, will the cell create functional protein from that plasmid only ...
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1answer
46 views

Are alleles passed down and shuffled randomly to the offspring during meiosis or fertilization?

If it does occur during meiosis, are the alleles switched over from one sister chromatid to the other during the crossing over process in Prophase I?
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1answer
44 views

Basic Gene/Chromosome/Genome/Protein question.. which comes first? [closed]

How are they ordered? Genes make up Chromosome, and Chromosomes make up a Genome... So, where does Protein come into play? What do you call Genes that are spliced together to form something new? ...
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1answer
305 views

Crossing white eyed Drosophila with sepia eye

So, I'm doing some drosophila experiments with my high schoolers and I had really poor production of wild type individuals for doing the experiment resulting in not enough to cross with everyone... I ...
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1answer
103 views

Can genetic engineering be performed without a laboratory setting? [closed]

I'm becoming more interested in genetic engineering as I learn more about it, and it's becoming more and more apparent that there's very few resources on genetic engineering at home. A similar ...
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1answer
52 views

How was the origin of CTVT parasitic cancer determined?

The wikipedia article on CTVT says that the tumor cell has 57-64 chromosome while a normal dog has 78 chromosomes. Similarly while all chromosomes in dogs except the X and Y chromosomes are ...
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1answer
192 views

After how many generations descendant is not more related to ancestor, than to a random individual in an ancestral population?

Descendant of n generation has on average 1/2n DNA of ancestor. (For example children have 1/2 DNA of parents and 1/4 DNA of Grandparents, After 10 Generation 1/1024 DNA and after 100 Generations ...
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1answer
39 views

Is it possible to estimate how much variation in common phenotypes is predicted by genetics?

Phenotypes such as; skin color, eye color, nose shape, lip size, limb proportions, and skull shape. Im trying to find a source for this quote. "If you ask what percentage of your genes is reflected ...
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1answer
60 views

What is Mendelian Segregation and how is it related to the Hardy-Weinberg equilibrium?

I can't find the exact definition of Mendelian segregation. In addition, I am wondering how it is related to the Hardy-Weinberg equilibrium?
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1answer
58 views

Could we engineer humans to behave like insects? [closed]

First off, though complex, I'm assuming insects are at an earlier evolutionary stage than humans. That being said, could humans be genetically engineered to behave like insects? I'm not talking about ...
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1answer
385 views

why is DNA antiparallel? Can it be parallel?

My biology textbook mentions that DNA is antiparallel and it got me wondering... Can DNA be parallel? What would happen if it was parallel? could DNA still replicate right?
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61 views

Known ways to modify the genetic structure of the 13 loci used in CODIS

After reading the answer to Does our DNA change during our lives?, I was wondering if and how it would be possible to change the structure of the 13 loci that are used in the CODIS database, in such a ...
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0answers
32 views

What log transformation and normalization functions are most commonly used for microarray and how to select them?

Need help on rational approach to choosing log transformation, standartization and normalization functions in microarray experiments. I am using Expander software and it provides Log2 transform and ...
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1answer
94 views

What to do if microarray t-test, ANOVA, SAM and LImma show various selected significant genes?

Need advice: how to approach discrepancy in differential microarray gene expression test results: what to do if ANOVA, ttest, SAM and Limma procedures show different results and especially more ...
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545 views

Father with mutated mtDNA- why isn't his offspring at risk?

Mothers transmit their mitochondria (and therefore mtDNA) to their offspring and fathers don't. Lets assume that father had a mutation of the gene that encodes mtDNA, would then be his offspring at ...
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1answer
75 views

Are there ways to speed up the growth of plants?

I'm interested in what humans can do to speed up the rate of growth in a plant. I'm interested in both the context of home gardening and large-scale, institution-backed projects. Obviously, optimal ...
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0answers
25 views

Is this description of etiology of celiac disease correct?

There is a detailed and, to my inexpert eyes, plausible description of the etiology of celiac disease and other autoimmune disorders posted here: http://no-gluten.org/CeliacDisease.htm Is it is at ...
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1answer
117 views

Why is an allele dominant or recessive? [duplicate]

Alleles refer to duplicate genes, where one allele can be dominant over the other. What makes an allele dominant or recessive, given that both code for a single protein?.
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2answers
55 views

What does the gene name “lexA” stand for?

It is an important gene expressed in E. coli that represses the SOS response and also the expression of lambda lytic phase genes. UV light and damage to DNA is responsible for its breakdown and hence ...
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1answer
50 views

When do the spindle fibers attach to the chromosome

At what phase does this occur in mitosis (or even meiosis); some text books say prophase while others say metaphase.
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1answer
60 views

Is probability for double crossing over included in distance cM? [task]

We got this task: There are 3 genes (acb) on one chromosome (linked inheritance). Distance a-c = 12cM, a-b=16cM. Probability for double crossing-over (CO) is 0,6%. Find ratio of genotypes of ...
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1answer
55 views

Supercomputer and undergraduates [closed]

Is it common for an undergraduate to run their thesis (evolutionary genomics) in a supercomputer? In my country, few supercomputers exist, but I'm not sure how it is for bachelors in the US or Europe. ...
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1answer
220 views

Why isn't the insertion of a single nucleotide destructive for DNA?

As far as I know proteins are built by sequentially reading triplets of nucleotides. But if at a certain point a nucleotide is inserted in the sequence, the following sequence of triplets is ...
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3answers
446 views

Why is mRNA needed in the Protein translation?

The original question was to predict the basic requirements for information storage. Then the discussion moved to why is it necessary to include mRNA in the protein translation process. Why can't ...
5
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1answer
87 views

What is an operon?

What is an operon in a eukaryotic cell, and how does it regulate the expression of genes? I've already read Wikipedia, but it is not enough clear to me. Unfortunately my knowledge in genetics are very ...
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2answers
92 views

Downloading specific yeast genes in an automated manner?

I have 6 genes of Candida albicans yeast namely orf19.723, orf19.5908, orf19.610, ...
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76 views

Blood type frequency given probability

I have calculated the probability that any child will have a particular blood type from both the genotype level and the phenotype level assuming the human ABO Rh system is followed. Here are the ...
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1answer
56 views

Will gene mutations give rise to a protein that is shorter than the full length protein?

What is the relationship between deletion or insertion of nucleotide in the gene sequence and the protein's length that is coded out from the mutated gene?
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3answers
210 views

Are domesticated animals really “more intelligent,” or is that a myth/misunderstanding?

Often do I hear people speaking of how the domestic house cats are more friendly, less ferocious, less savage-like, and smarter and/or than their distinct but equivalent feline-species friends, like ...
2
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1answer
52 views

G>T transversion VS. T>G transversion?

So I'm reading about how mutations in DNA can be caused by oxidative damage. An example of a product of oxidative damage is given: 8-oxo-7-hydrodeoxyguanosine My textbook says that this product ...
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0answers
53 views

Are the Chromosomes organized in any meaningful way? [closed]

So my major is in pharmacy but both my master and my (currently in progress) doctoral degree are both in theoretical chemistry. My thesis is about quantum chemistry and proteins, but it has a certain ...
3
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1answer
61 views

Why do some animals try to imitate other animals?

There is a tendency of some animals (including people!) to be "copy-cats" and try to imitate members of their own, and sometimes other, species. The most obvious example is a parrot copying human ...
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1answer
19 views

What does 'pedigree information' mean?

This paper uses Pied Flycatcher as a study species. For the population of Pied Flycatchers they studied, 'pedigree information' was available. What exactly does this 'pedigree information' mean?
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1answer
103 views

Circulating factors affecting human health/longevity

Circulating factors present in young mice have been shown to promote rejuvenation of aged mice, suggesting that tissues have inherent capabilities to regenerate, and circulating factors may be ...
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1answer
142 views

Why do we still have genetic disorders that show anticipation?

Anticipation whereby symptoms of genetic disorders occur earlier and with more severity as it is passed from one generation to the next. So wouldn't these inherited diseases over a few hundred ...
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0answers
17 views

Resource for finding Repressive/Inhibitory factors for a given gene?

I have a list of genes for each of which I'd like to find: A list of transcription factors that up-regulate the gene A list of inhibitory factors that down-regulate it. I used this tool on ...
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1answer
33 views

PCR cycle problem [closed]

IF I began a PCR cycle with 5 copies of a particular DNA section, and copied the section by PCR, for 6 cycles, how many copies of the DNA (include the originals) would I have by the end of these ...